Madison Science Pub for March, Madison, WI

Posted 19 March 2012 by

Our March event will feature Dr. Clark Johnson, Principal Investigator at the Wisconsin Astrobiology Research Consortium. Dr. Johnson will discuss the origin of life, and the evolution of life on Earth. How do we go about such a challenge? What do we look for? What do we know so far? How does our knowledge of the evolution of life on Earth help, or hurt, our search for life on other planets such as Mars? These are some of the questions that astrobiology research is engaged in. March 25 Science Pub 2PM, Brocach Irish Pub 7 W Main Street, Madison, WI

64 Comments

Just Bob · 20 March 2012

Absolutely fascinating subjects! If I lived within a couple of hours I'd be there.

How do creationists go about approaching those questions? "There is no 'astrobiology' because there is no evolution and God only created life once, on Earth...because the Bible says so." Then when extraterrestrial biology is discovered, they will suddenly "discover" that the Bible said there was all along.

Challenge to anyone with too much time on his hands: find one or more passages in the Bible that COULD be interpreted to mean that there is life elsewhere.

Dave Luckett · 20 March 2012

You called?

Isaiah 47:26: "Lift up your eyes to the heavens; consider who created these, led out their host one by one, and summoned each by name. Through his great might, his strength and power, not one is missing."

Yes, yes. Too much time.

Just Bob · 20 March 2012

And Christians thought all along that referred to the stars, or maybe angels. Babes in the wood!

Carl Drews · 20 March 2012

It's lunchtime here. Biblical exegesis can be great fun if you're trying to understand the meaning of the text and not stuck trying to defend what Bishop James Ussher said in 1650. :-) I am not a creationist. I think Isaiah 40:26 is more likely referring to the individual stars, not the life forms; but it is quite an acceptable entry under the terms of the challenge. :-) Consider the "let the earth/waters bring forth" verses in Genesis 1:11, 20, and 24. The English word "earth" here is "erets" in Hebrew, Strong's Concordance H776. Water is mayim H4325. The Blue Letter Bible lists one possible meaning of "eretz" as:
c) ground, surface of the earth 1) ground 2) soil
Dirt + water => life So wherever there are minerals and liquid water together in the universe, there is a good possibility that life arose there. Which is the same thing that exobiology says. Ta-dah!

harold · 20 March 2012

Which is the same thing that exobiology says.
I'm not sure exobiology says that, exactly. In some ways, ironically, the idea of detecting "intelligent" life is almost easier. After all, if that intelligent being communicates, there you go. Once you start talking about "life", all of the questions listed above kick in. What is life? Does it have to be based on nucleic acids, proteins, carbohydrates, and lipids? If it isn't similar in biochemistry, how are we going to recognize it? If we are looking for something similar to terrestrial life, what basis do we have for making any assumption whatsoever about how common that will be. To be clear, I am interested in and enthusiastic about abiogenesis and exo/astrobiology. Having said that, these remain areas of great mystery. We have some decent hypothetical models for some aspects of abiogenesis.

Henry J · 20 March 2012

What is life? Does it have to be based on nucleic acids, proteins, carbohydrates, and lipids? If it isn’t similar in biochemistry, how are we going to recognize it?

Living things eat, poop, grow, and reproduce. If things are found that do all of those, it would be a prime suspect in the search for life.

harold · 20 March 2012

Henry J said:

What is life? Does it have to be based on nucleic acids, proteins, carbohydrates, and lipids? If it isn’t similar in biochemistry, how are we going to recognize it?

Living things eat, poop, grow, and reproduce. If things are found that do all of those, it would be a prime suspect in the search for life.
Define each of those precisely, with special emphasis on how you will recognize each in the context of a completely novel biochemistry. Do you think that all of these, as you define them, are required to identify life?

Henry J · 20 March 2012

I think the things I listed are rough guidelines. With a completely novel biochemistry, stationary life forms could easily go unrecognized. So if something is seen to be growing, maybe throw some researchers at it and see if they figure out what it is?

Atheistoclast · 20 March 2012

I really wish we had more science pub meetings! It would great to be present among evolutionists all drinking beer and talking about how fish crawled out of the water to conquer the land. I propose setting up my own. Anyone game?

garystar1 · 20 March 2012

@Atheistoclast: I'm a long-time lurker, and your comment forced me to ask, "What's the joke?" To me, your comment was analogous to, "Hey! Let's sit around, drink beer and discuss how when the quarterback throws a football, it comes back towards the ground!"
I'm guessing fear makes people say strange things and, mister, you say some really strange things.

Paul Burnett · 20 March 2012

Atheistoclast said: I really wish we had more science pub meetings! ... I propose setting up my own. Anyone game?
If it would keep you occupied away from PT, I would be all for it.

Atheistoclast · 21 March 2012

garystar1 said: @Atheistoclast: I'm a long-time lurker, and your comment forced me to ask, "What's the joke?" To me, your comment was analogous to, "Hey! Let's sit around, drink beer and discuss how when the quarterback throws a football, it comes back towards the ground!" I'm guessing fear makes people say strange things and, mister, you say some really strange things.
Aha...another "Evolution is as matter of fact as Gravity" comments. Sure, we can discuss the laws of physics and chemistry as well. Personally, I think most evolutionists take hard drugs to say all the silly things that they do.

DS · 21 March 2012

garystar1 said: @Atheistoclast: I'm a long-time lurker, and your comment forced me to ask, "What's the joke?" To me, your comment was analogous to, "Hey! Let's sit around, drink beer and discuss how when the quarterback throws a football, it comes back towards the ground!" I'm guessing fear makes people say strange things and, mister, you say some really strange things.
He's just trying to get someone to give him some personal informations. Then, when he finds out who you are and where you live, he will stalk you until you get a restraining order. He does this a lot, especially with scientists. The science envy is strong in this one. He obviously takes drugs in order to give the illusion of normality. Time for another dump to the bathroom wall for the socially and intellectually challenged.

Karen S. · 21 March 2012

I really wish we had more science pub meetings! … I propose setting up my own.
Yes. Call your pub the Bathroom Wall.

Atheistoclast · 21 March 2012

DS said: Time for another dump to the bathroom wall for the socially and intellectually challenged.
I look forward to reading your scientific papers...the ones you haven't written. Meanwhile... http://scholar.google.co.uk/scholar?q=%22joseph+bozorgmehr%22&hl=en&btnG=Search&as_sdt=1%2C5&as_sdtp=on You can only dream.

Rolf · 21 March 2012

Atheistoclast said: I really wish we had more science pub meetings! It would great to be present among evolutionists all drinking beer and talking about how fish crawled out of the water to conquer the land. I propose setting up my own. Anyone game?
I ignore AC as much as I can, but this time I find his comment out of this world! Here's what he should have written, he migh even have earned some resepect instead of the regular headshaking: "I really wish we had more ID creationism pub meetings! It would great to be present among ID-iots all drinking root beer and talking about how God created all the endless forms most beautiful - that somehow managed to adapt and survive the wildly changing conditions on the young planet! I propose setting up my own." Please do! I presume Dembski, Behe, Robert Byers and Ray Martinez will be among your first enthusiastic guests. You have so much to discuss! Creationism is so much more interesting and rewarding than science! To discover who did what where and when, all the tremedous research projects!

Atheistoclast · 21 March 2012

Rolf said: "I really wish we had more ID creationism pub meetings! It would great to be present among ID-iots all drinking root beer and talking about how God created all the endless forms most beautiful - that somehow managed to adapt and survive the wildly changing conditions on the young planet! I propose setting up my own."
Our first subject will be a discussion about the crocodile which has been around (largely unchanged) for the last 100 million years in spite of all the wildly changing conditions on the planet! http://www.youtube.com/watch?v=yZq8ZUE6GTU We can then head off the next day to church to sing "All things bright and beautiful, all creatures great and small....the Lord God made them all." What do you say to this proposal?

Just Bob · 21 March 2012

Don't forget to include a bit about why the crocodile is in such a RARE category: largely unchanged for the last 100 million years.

And where all the dolphins, chimpanzees, and hummingbirds were then.

SWT · 21 March 2012

Just Bob said: Don't forget to include a bit about why the crocodile is in such a RARE category: largely unchanged for the last 100 million years. And where all the dolphins, chimpanzees, and hummingbirds were then.
The crocodiles ate them, of course.

Kevin B · 21 March 2012

Atheistoclast said:
Rolf said: "I really wish we had more ID creationism pub meetings! It would great to be present among ID-iots all drinking root beer and talking about how God created all the endless forms most beautiful - that somehow managed to adapt and survive the wildly changing conditions on the young planet! I propose setting up my own."
Our first subject will be a discussion about the crocodile which has been around (largely unchanged) for the last 100 million years in spite of all the wildly changing conditions on the planet! http://www.youtube.com/watch?v=yZq8ZUE6GTU
Perhaps it's because crocodilians are well-adapted to cope with wildly changing conditions.
We can then head off the next day to church to sing "All things bright and beautiful, all creatures great and small....the Lord God made them all."
No doubt including the verse
Cecil Frances Alexander wrote: The rich man in his castle, The poor man at his gate, He made them, high or lowly, And order'd their estate.
What do you say to this proposal?
Tick, tock? http://www.youtube.com/watch?v=XNwhwwuRnB0&feature=fvst

DS · 21 March 2012

Skip,

I warned you. If you don't want twenty more pages of ignorant off-topic crap like this, dump the troll to the bathroom wall now. Otherwise, this is all you can expect.

harold · 21 March 2012

I think Atheistoclast should definitely start drinking more beer (CAVEAT - assuming normal liver function, no existing diagnosis of celiac sprue, etc). I support anything that furthers that. It will either improve him or exacerbate his tendencies to the point of bringing him in contact with those with the expertise to help him.

Initially, I was hesitant to make this somewhat unconventional recommendation, because even in the relatively low crime environment of the UK, law enforcement personnel have enough on their plates. But I've thought it over, and I think it's a good idea.

Atheistoclast · 21 March 2012

DS said: Skip, I warned you. If you don't want twenty more pages of ignorant off-topic crap like this, dump the troll to the bathroom wall now. Otherwise, this is all you can expect.
Can I find references to your published papers in the Bathroom Wall? *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..

phhht · 21 March 2012

Atheistoclast said:
DS said: Skip, I warned you. If you don't want twenty more pages of ignorant off-topic crap like this, dump the troll to the bathroom wall now. Otherwise, this is all you can expect.
Can I find references to your published papers in the Bathroom Wall? *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..
What a ludicrous little prawn you are. No one gets respect by demanding it. The only people who do that are those who will never have it. You're a deluded fool, Theistoclast.

Karen S. · 21 March 2012

I think Atheistoclast should definitely start drinking more beer (CAVEAT - assuming normal liver function, no existing diagnosis of celiac sprue, etc).
An intelligent designer would have made better livers.

Robin · 21 March 2012

Atheistoclast said: *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..
Atheistoclast said: *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..
Hahahahahaha! What a maroon! Here's a clue for you "Dr. Scientist": respect is not an entitlement; you have earn it ding-bat. Posting crap on scientific message boards is a sure way of NOT earning respect, but rather earning disdain and mockery. Thus far your batting 1000 on the latter, but you'll have to give some respect to others here before anyone is going to respect you.

Rumraket · 21 March 2012

Guys, don't be too hard on Clastie, he's been temporarily suspended on rationalskepticism.org (for misrepresentations of other people's words and work) and is in desperate need of a little attention.

DS · 21 March 2012

I did warn you Skip.

DS · 21 March 2012

Atheistoclast said:
DS said: Skip, I warned you. If you don't want twenty more pages of ignorant off-topic crap like this, dump the troll to the bathroom wall now. Otherwise, this is all you can expect.
Can I find references to your published papers in the Bathroom Wall? *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..
I posted a paper that disproves your "hypothesis" about evo devo. Funny you haven't bothered to read it or comment on it and yet you demand respect. You haven't earned any. You will get none.

Atheistoclast · 21 March 2012

DS said:
Atheistoclast said:
DS said: Skip, I warned you. If you don't want twenty more pages of ignorant off-topic crap like this, dump the troll to the bathroom wall now. Otherwise, this is all you can expect.
Can I find references to your published papers in the Bathroom Wall? *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..
I posted a paper that disproves your "hypothesis" about evo devo. Funny you haven't bothered to read it or comment on it and yet you demand respect. You haven't earned any. You will get none.
I saw no paper...certainly not one written by a scientifically illiterate young whipper-snapper like yourself. Face it DS, you lied about having a publication record..right on this very site in front of millions of people. You have also defamed scientists like myself who work hard to get their work published.

DS · 21 March 2012

Atheistoclast said:
DS said:
Atheistoclast said:
DS said: Skip, I warned you. If you don't want twenty more pages of ignorant off-topic crap like this, dump the troll to the bathroom wall now. Otherwise, this is all you can expect.
Can I find references to your published papers in the Bathroom Wall? *RESPECT*...I am a published scientist while you are not. Honor thy betters, you insolent puppy..
I posted a paper that disproves your "hypothesis" about evo devo. Funny you haven't bothered to read it or comment on it and yet you demand respect. You haven't earned any. You will get none.
I saw no paper...certainly not one written by a scientifically illiterate young whipper-snapper like yourself. Face it DS, you lied about having a publication record..right on this very site in front of millions of people. You have also defamed scientists like myself who work hard to get their work published.
Right. Now all you have to do is prove it. But of course you don't have any evidence of that either now do you Joe. All you got is lies and deceit.

DS · 21 March 2012

DS said: If you want to read a paper, how about this one: Loehlin and Werren (2012) Evolution of shape by multiple regulatory changes to a growth gene. Science 335:(6071):943-947. From the conclusion: It has also been argued that noncoding cis-regulatory changes could play a central role in developmental differences between species. Our findings support this view and further implicate growth-regulating genes in organ-specific size and shape evolution.
Here is the paper I posted on the bathroom wall for you Joe. So I guess you lied about that as well. I would be more than happy to discuss this paper on the bathroom wall, where you belong. You don't deserve the respect of having a discussion on a regular thread with decent folks.

harold · 21 March 2012

Our first subject will be a discussion about the crocodile which has been around (largely unchanged) for the last 100 million years in spite of all the wildly changing conditions on the planet!
I'll bother to mention that there are many lineages that seem not to have changed much in morphology over that time period, including the less glamorous cockroach. The thought implied here is a variation on the "why are there still monkeys?" meme.

DS · 21 March 2012

harold said:
Our first subject will be a discussion about the crocodile which has been around (largely unchanged) for the last 100 million years in spite of all the wildly changing conditions on the planet!
I'll bother to mention that there are many lineages that seem not to have changed much in morphology over that time period, including the less glamorous cockroach. The thought implied here is a variation on the "why are there still monkeys?" meme.
Well as long as the thread is already derailed, I guess I should add that Harold is correct. Just because a species was not changing very much in morphology, especially not in morphology preserved in the fossil record, doesn't mean that it remained constant and unchanging. It was most certainly changing on the genetic level, which is after all the important level for evolution. To assume otherwise is unwarranted. Apparently Joe is off his meds again. He does that every once in a while, barges his way unto unmoderated threads, makes inflammatory statements, picks fights, demands respect and starts hurling insults. This is usually accompanied by some kind of publication pissing contest and crowing about his irrelevant papers. Apparently he hasn't figured out that this is not the way real scientists behave. By their works ye shall know them indeed.

Atheistoclast · 21 March 2012

harold said: I'll bother to mention that there are many lineages that seem not to have changed much in morphology over that time period, including the less glamorous cockroach. The thought implied here is a variation on the "why are there still monkeys?" meme.
Yes, you'd think Patas monkeys would have evolved bipedalism by now given the fact that they live in a terrestrial environment. Stasis, I'm afraid, is far more prevalent than change. Btw, the dinosaurs did not die off because they couldn't adapt to normal environmental changes. They were wiped out by some meteorite....or so we are told. I remain skeptical.

DS · 21 March 2012

So that would be a no. Joe still hasn't read the paper and still has no answers. Got it. How surprising.

Now he's going into the old song and dance routine that if something doesn't happen all the time it can't happen at all. No one is fooled by that crap.

TIme to close the thread Skip. Why give the troll a free playground?

garystar1 · 21 March 2012

DS said: Well as long as the thread is already derailed,
My fault! Totally my fault! I fed the troll! I profusely apologize to the rational readers who actually want to exchange valid ideas. I'll go back to my lurker mode. I'll (probably) do less damage that way.

shebardigan · 21 March 2012

Atheistoclast said:
I remain skeptical.
As usual, the total mass of evidence for this assertion approaches the cube root of zero asymptotically.

Vaughn · 21 March 2012

harold said:
Henry J said:

What is life? Does it have to be based on nucleic acids, proteins, carbohydrates, and lipids? If it isn’t similar in biochemistry, how are we going to recognize it?

Living things eat, poop, grow, and reproduce. If things are found that do all of those, it would be a prime suspect in the search for life.
Define each of those precisely, with special emphasis on how you will recognize each in the context of a completely novel biochemistry. Do you think that all of these, as you define them, are required to identify life?
Moving this thread back on topic, I agree with Henry that those four characteristics are needed, but I would also add: cellularity, irritability, and evolution. The metabolism implied in "eat" and "poop" requires a cell membrane to localize the substrates, enzymes, and products of chemical pathways, thus being cellular is absolutely essential to "life". Responding to stimuli as an individual organism (irritability) or as a population (evolution) also is needed for survival. Defining Henry's terms regardless of biochemistry is relatively straightforward: eat - obtain energy from the environment poop - excrete waste chemicals into the environment grow - increase cell number or cell size reproduce - create progeny that resemble the parent(s) So, I would think that those 7 characteristics would be what one should look for to identify extraterrestrial life. Too bad I can't be in Madison to hear Dr. Johnson's thoughts.

RWard · 22 March 2012

So, I would think that those 7 characteristics would be what one should look for to identify extraterrestrial life. Too bad I can't be in Madison to hear Dr. Johnson's thoughts.
If your probe found a virus-like thing in deep space you wouldn't consider it life?

harold · 22 March 2012

I'm going to have to strongly disagree again that any of this is necessarily "straightforward". Now, of course, it will be straightforward to recognize extraterrestrial life, and indeed, to forgo any consideration of the "definition of life" if, as you have implicitly assumed, it is either identical to or extremely and obviously similar to terrestrial life in biochemistry. That is essentially your point. If extraterrestrial life is highly, highly similar to terrestrial life, we'd have to be morons not to recognize it. Yes, I guess that's true.
Defining Henry’s terms regardless of biochemistry is relatively straightforward: eat - obtain energy from the environment
Let's see - "eat", yes, as long as you include photosynthesis - the primary way the terrestrial biosphere harvests energy - the rest of "eating" is redistribution of harvested solar energy. It might make sense to hope that other biological systems that harvest relatively narrow ranges of EM radiation as a primary energy source could be recognized. However, would it necessarily be visible light?
excrete waste chemicals into the environment
Yes, presumably any biological system would do this in some way. "Waste" in an anthropormorphic term; I'll leave the teleology to creationists, but reactions that transduce chemical energy will leave by-products.
grow - increase cell number or cell size
Most of life on earth is unicellular and doesn't ever increase cell number per organism. It is hypothesized, reasonably, that all life on earth was unicellular, for a long period of time. Most unicellular organisms do change cell size from time to time, but that could be equally described as "swelling" and "shrinking". Unicellular organisms sometimes form "colonies" and seem to "communicate", here on earth, via chemical messengers, but that isn't usually considered to represent "growth", "clustering" would be a better term. All multicellular individuals do grow/develop via organized cell division/differentiation at some point during their life cycle. Still, this one is highly debatable as either a requirement, or a defining characteristic. Many things that are not living can swell and shrink.
reproduce - create progeny that resemble the parent(s)
I'm sure we'd all agree that this would have to be a defining characteristic of "life". (Of interest, science fiction sometimes depicts "awareness" in entities that can't reproduce, such as computers. We don't really need to dwell much on that except to notice that "awareness" and "life" can be conceived of as quite separate concepts.)
The metabolism implied in “eat” and “poop” requires a cell membrane to localize the substrates, enzymes, and products of chemical pathways, thus being cellular is absolutely essential to “life”
This is intriguing on a number of levels. First of all, it makes a statement about the definition of life that some people working in abiogenesis might not be comfortable with. Self-replicating systems that aren't enclosed in a micro-environment (by which I mean any locally enclosed, self-created environment, regardless of gross scale) are not considered "life" here. Now actually, I'm fine with that, although it does illustrate the trickiness of the concept of a "definition of life". But the next point is that you seem, if I'm not mistaken, to assume that such cellularity, broadly defined, is necessarily similar to terrestrial cellularity in terms of membrane biochemistry and scale.
Responding to stimuli as an individual organism (irritability)
It's also common for humans, as active animals, to overlook the vast proportion of even the terrestrial biosphere that does not show much motile response to the environment. Irritability refers to a characteristic of organisms with a nervous system (yes, that is what the word means in this context, however, if you dispute that, I concede in advance). Even motility at the most basic level is highly questionable as a defining requirement. Independent motility would, of course, be a strong piece of evidence that something was living by a reasonable definition of life (not the same thing as being a requirement for life).
or as a population (evolution) also is needed for survival.
Evolution is not a deliberate response to the environment. Having said that, I do agree that any reasonably defined "life" will evolve. Any self-replication has to be imperfect, any population of individuals thus has to have some variation within it, and some variants will inevitably have a higher expected value of descendants than other variants.

harold · 22 March 2012

RWard said:
So, I would think that those 7 characteristics would be what one should look for to identify extraterrestrial life. Too bad I can't be in Madison to hear Dr. Johnson's thoughts.
If your probe found a virus-like thing in deep space you wouldn't consider it life?
If you find a virus here on earth, do you consider it life? All terrestrial viruses are dependent of actual cells for reproduction (by definition). The existence of viruses, which are independent but obligate parasitic self-replicators, causes "definition of life" issues right here on earth.

Atheistoclast · 22 March 2012

I really think that there needs to be a national dialog on evolution that involves more direct contact between the public and scientists. This is why science pub sessions are useful. I get the feeling that many scientists live in ivory towers and hold the public in disdain even through they fund their activities indirectly.

Despite the fact that I myself am an intellectual, and a successful published scientist , I hold deeply anti-intellectual antipathies towards the scientific establishment and academics in general. I think there are too many vested interests and entrenched attitudes out there. We need more freedom of thought and debate.

DS · 22 March 2012

Atheistoclast said: I really think that there needs to be a national dialog on evolution that involves more direct contact between the public and scientists. This is why science pub sessions are useful. I get the feeling that many scientists live in ivory towers and hold the public in disdain even through they fund their activities indirectly. Despite the fact that I myself am an intellectual, and a successful published scientist , I hold deeply anti-intellectual antipathies towards the scientific establishment and academics in general. I think there are too many vested interests and entrenched attitudes out there. We need more freedom of thought and debate.
I absolutely agree. Especially about the part where you say you are deeply anti-intellectual.

Just Bob · 22 March 2012

A little DA (devil's advocate).

"Any self-replication has to be imperfect, any population of individuals thus has to have some variation within it, and some variants will inevitably have a higher expected value of descendants than other variants."

Could we imagine an environment that has remained stable over, say, several billion years? Maybe an ice-dwarf planet orbiting a red dwarf. Imagine a single species that has evolved to a "plateau". It survives handily in its absolutely unchanging environment, and mutations, being generally harmful, do the species more harm than good. So it has evolved the ability to stop evolving. Reproductive variation is nonexistent. Mechanisms exist to check and double-check and cross-check and correct or eliminate any variation in the "seed" of the new generation.

Maybe there could be more than one species like that--not competing, certainly, but cooperating and dependent on each other, or inhabiting completely separate ecological niches.

Could there be an environment like that where conditions are so stable over geological time that evolution has essentially stopped, and the life there has completely lost the ability to evolve?

RWard · 22 March 2012

If you find a virus here on earth, do you consider it life? All terrestrial viruses are dependent of actual cells for reproduction (by definition). The existence of viruses, which are independent but obligate parasitic self-replicators, causes "definition of life" issues right here on earth.
Yes, actually I do. Viruses, like most parasitic organisms, are simplified and degenerate. They have lost unnecessary structure & function. That's an evolutionary outcome. Viruses are highly evolved, successful organisms. Failure to meet some 60-year-old seven part definition doesn't change that.

harold · 22 March 2012

Just Bob said: A little DA (devil's advocate). "Any self-replication has to be imperfect, any population of individuals thus has to have some variation within it, and some variants will inevitably have a higher expected value of descendants than other variants." Could we imagine an environment that has remained stable over, say, several billion years? Maybe an ice-dwarf planet orbiting a red dwarf. Imagine a single species that has evolved to a "plateau". It survives handily in its absolutely unchanging environment, and mutations, being generally harmful, do the species more harm than good. So it has evolved the ability to stop evolving. Reproductive variation is nonexistent. Mechanisms exist to check and double-check and cross-check and correct or eliminate any variation in the "seed" of the new generation. Maybe there could be more than one species like that--not competing, certainly, but cooperating and dependent on each other, or inhabiting completely separate ecological niches. Could there be an environment like that where conditions are so stable over geological time that evolution has essentially stopped, and the life there has completely lost the ability to evolve?
Certainly we could, but what I said would still be true. In fact we see this situation, albeit not for such long time spans, quite often, on earth. When a population is highly adapted to a stable environment, it's still absolutely true that some variants will inevitably have a higher expected value of descendants than other variants. Basically, in a highly adapted population in an long-established stable environment, novel mutations and recombinations that impact on phenotype are more likely to be selected against than selected for. The variants that are highly similar to recent ancestors will have a stronger advantage, relatively to more novel variants, in such an environment.

harold · 22 March 2012

RWard said:
If you find a virus here on earth, do you consider it life? All terrestrial viruses are dependent of actual cells for reproduction (by definition). The existence of viruses, which are independent but obligate parasitic self-replicators, causes "definition of life" issues right here on earth.
Yes, actually I do. Viruses, like most parasitic organisms, are simplified and degenerate. They have lost unnecessary structure & function. That's an evolutionary outcome. Viruses are highly evolved, successful organisms. Failure to meet some 60-year-old seven part definition doesn't change that.
I don't disagree with any of this, except that I personally do not know (or strongly care) whether or not viruses are best defined as "organisms" or "living". We both agree that they seem to have evolved from and are parasitic on intact cells. A recognition of a virus would imply that there must be cells around somewhere near, or must have been. I really wouldn't know what to make of a virus particle in deep space, to get back to the original question. Released with the garbage from an alien spacecraft? Was on the outer surface at launch of a spacecraft, earth or alien, that went elsewhere?

harold · 22 March 2012

harold said:
Just Bob said: A little DA (devil's advocate). "Any self-replication has to be imperfect, any population of individuals thus has to have some variation within it, and some variants will inevitably have a higher expected value of descendants than other variants." Could we imagine an environment that has remained stable over, say, several billion years? Maybe an ice-dwarf planet orbiting a red dwarf. Imagine a single species that has evolved to a "plateau". It survives handily in its absolutely unchanging environment, and mutations, being generally harmful, do the species more harm than good. So it has evolved the ability to stop evolving. Reproductive variation is nonexistent. Mechanisms exist to check and double-check and cross-check and correct or eliminate any variation in the "seed" of the new generation. Maybe there could be more than one species like that--not competing, certainly, but cooperating and dependent on each other, or inhabiting completely separate ecological niches. Could there be an environment like that where conditions are so stable over geological time that evolution has essentially stopped, and the life there has completely lost the ability to evolve?
Certainly we could, but what I said would still be true. In fact we see this situation, albeit not for such long time spans, quite often, on earth. When a population is highly adapted to a stable environment, it's still absolutely true that some variants will inevitably have a higher expected value of descendants than other variants. Basically, in a highly adapted population in an long-established stable environment, novel mutations and recombinations that impact on phenotype are more likely to be selected against than selected for. The variants that are highly similar to recent ancestors will have a stronger advantage, relatively to more novel variants, in such an environment.
Also, 1) No terrestrial environment is perfectly stable, pathogens and parasites will always be evolving, even if that is less obvious to human eyes. 2) Even if an environment were very stable and morphologic/physiologic phenotype were maintained, and we do see those maintained over long periods of time in some cases, there will still always be "change in frequency of alleles", because mutations with no impact or neutral impact on phenotype will arise and spread stochastically.

Just Bob · 22 March 2012

harold said: 2) Even if an environment were very stable and morphologic/physiologic phenotype were maintained, and we do see those maintained over long periods of time in some cases, there will still always be "change in frequency of alleles", because mutations with no impact or neutral impact on phenotype will arise and spread stochastically.
What I'm suggesting is a situation where there is NO change in frequency of alleles, because the organisms have evolved biochemical mechanisms to prevent all variation. IANAS, but I understand that there are "correcting" mechanisms in earthly cells that attempt to repair DNA damage and thus slow down the rate and intensity of variation. (But luckily for us, that's not 100% effective.) I'm suggesting a biome where that IS 100% effective: either all variations are "corrected" or they are destroyed before "birth". Fantasy? Sure, but could it ever work that way?

Vaughn · 22 March 2012

Harold, I interpreted your comments as "thinking out loud" about my statements and their extensions. Please read my comments here in the same vein.
harold said: I'm going to have to strongly disagree again that any of this is necessarily "straightforward". Now, of course, it will be straightforward to recognize extraterrestrial life, and indeed, to forgo any consideration of the "definition of life" if, as you have implicitly assumed, it is either identical to or extremely and obviously similar to terrestrial life in biochemistry. That is essentially your point.
Yes, I was using "straightforward" to indicate the necessity of starting with our knowledge about terrestrial life in order to identify potential extraterrestrial life. I did not mean that identifying extraterrestrial life will be straightforward.
Let's see - "eat", yes, as long as you include photosynthesis....
I always start my introductory Bio students on the animal-centric word "eat" to get them to think about the physiological function of eating. We (animals) eat in order to obtain energy, carbon for manufacturing macromolecules, and micronutrients (those needed elements and compounds we cannot synthesize). Once those three functions are identified, we can expand our view of the other kingdoms of life to see that ALL terrestrial life collects energy and elements/chemicals from the environment. How can we extend this to extraterrestrial life? Well, if there is a life form with a completely novel biochemistry, it may not need to collect elements or compounds from the environment, but certainly it would need to collect energy. Thus extraterrestrial life (ETL from here on) should harvest SOME form of environmental energy. Whether it would be human-visible light, we can't a priori say.
"Waste" in an anthropormorphic term; I'll leave the teleology to creationists, but reactions that transduce chemical energy will leave by-products.
"Poop" is an anthropocentric term, but "waste" is not. All terrestrial organisms produce chemical wastes. I say to my intro Bio students, "One organism's poop is another's food. Humans eat the poop from other organisms." And after the expressions of disgust die down, I continue, "Yeast poop is especially tasty. (switching into my best Homer Simpson voice) Beer and doooonuuuts. Mmmmmmmm." And since those chemical wastes are un-useable and toxic to each organism (thus the reason they are legitimately termed "waste"), they are eliminated into the environment. ETL might similarly produce wastes, regardless of biochemistry, but I concede this is the least useful way of identifying ETL.
grow - increase cell number or cell size
Most of life on earth is unicellular and doesn't ever increase cell number per organism. It is hypothesized, reasonably, that all life on earth was unicellular, for a long period of time. Most unicellular organisms do change cell size from time to time, but that could be equally described as "swelling" and "shrinking".
In my classes, I expand upon my soundbite definition of growth given above to differentiate "growing" from "swelling". True growth requires the manufacture of new molecules to increase the volume of cytoplasm and membrane. Therefore, absorbing water and diluting the cytoplasm is not "growth". For identifying ETL, this characteristic of terrestrial life might also be problematic. Terrestrial (cellular) growth is almost always a precursor to reproduction; cells that are post-mitotic typically do not grow. Thus, we could imagine an ETL organism that only reproduces once every decade with its only growth occurring in a burst just prior to that reproduction event. Such sporadic growth would be difficult to discover. Thus, similar to "pooping", growth is probably not useful for identifying ETL.
The metabolism implied in “eat” and “poop” requires a cell membrane to localize the substrates, enzymes, and products of chemical pathways, thus being cellular is absolutely essential to “life”
This is intriguing on a number of levels. First of all, it makes a statement about the definition of life that some people working in abiogenesis might not be comfortable with. Self-replicating systems that aren't enclosed in a micro-environment (by which I mean any locally enclosed, self-created environment, regardless of gross scale) are not considered "life" here.
I think cellularity is the single best defining characteristic of terrestrial life (and the primary reason I disagree with RWard, and agree with you that viruses are not alive). I think ONLY when the chemical reactions of life, regardless of chemistry involved (carbon-based, silicon-based, germanium-based, etc.), occur within a limiting boundary, do we have something that is similar enough to terrestrial life that we could recognize it as "alive". I do not think that the boundary must be a lipid bilayer, but it must be SOMEthing to limit diffusion of the molecules that would comprise this ETL life form.
Responding to stimuli as an individual organism (irritability)
It's also common for humans, as active animals, to overlook the vast proportion of even the terrestrial biosphere that does not show much motile response to the environment. Irritability refers to a characteristic of organisms with a nervous system (yes, that is what the word means in this context, however, if you dispute that, I concede in advance).
I was using "irritability" in its broad-sense meaning that includes any response to an environmental stimulus, including the intracellular chemical cascades that occur when an environmental ligand binds to its cell-surface receptor. I believe you were thinking of the narrow-sense meaning that is common to the medical profession.
or as a population (evolution) also is needed for survival.
Evolution is not a deliberate response to the environment.
I agree. I was lumping irritability and evolution as "responses to environmental change" and wanted to distinguish the individual (including individual cells) phenomenon from the population phenomenon. And yes, I know that environmental change is not needed for evolution to occur, but as you point out, we should expect ETL to have imperfect replication of their hereditary molecules (be they DNA or something else) and thus demonstrate evolution of their populations over generations of time.

harold · 22 March 2012

Just Bob said:
harold said: 2) Even if an environment were very stable and morphologic/physiologic phenotype were maintained, and we do see those maintained over long periods of time in some cases, there will still always be "change in frequency of alleles", because mutations with no impact or neutral impact on phenotype will arise and spread stochastically.
What I'm suggesting is a situation where there is NO change in frequency of alleles, because the organisms have evolved biochemical mechanisms to prevent all variation. IANAS, but I understand that there are "correcting" mechanisms in earthly cells that attempt to repair DNA damage and thus slow down the rate and intensity of variation. (But luckily for us, that's not 100% effective.) I'm suggesting a biome where that IS 100% effective: either all variations are "corrected" or they are destroyed before "birth". Fantasy? Sure, but could it ever work that way?
That does sound like something that would be impossible to me, yes. It doesn't seem to fit with what we know about physics and chemistry. While part of my point here has been that maybe we shouldn't rely too heavily on the specific features of terrestrial life when we think about extra-terrestrial life, the idea of a self-replicating system that can perfectly replicate itself without any variability seems essentially impossible to me.

SWT · 22 March 2012

harold said: ... the idea of a self-replicating system that can perfectly replicate itself without any variability seems essentially impossible to me.
I pondered something like this, motivated by what some of our creationist friends assert. If there were indeed fixed "kinds" based on genetics, a designer could, in principle, dramatically reduce variability through a number of means -- for example, making the genetic code less forgiving of errors or adding a fourth base pair to the codon (maybe even serving as a checksum). I suspect that an organism with such a genome would be extremely fragile, and species would be (by construction) incapable of adapting to changing environmental conditions. My informal conclusion was that if the genomes we've come across in nature are designed (and I don't see any reason to believe that's the case), they're designed to evolve.

Atheistoclast · 22 March 2012

SWT said: My informal conclusion was that if the genomes we've come across in nature are designed (and I don't see any reason to believe that's the case), they're designed to evolve.
The benefit to an imperfect replication system is two-fold: 1) It allows for flexibility and versatility. 2) It serves to control reproductive fitness by reducing it. The reason why genomes are *designed* is because they contain complex specified information (I mean by this the various sequence motifs) that natural processes alone cannot produce. Unfortunately, folks like Joe Felsenstein are in abject denial about this.

DS · 22 March 2012

Atheistoclast said:
SWT said: My informal conclusion was that if the genomes we've come across in nature are designed (and I don't see any reason to believe that's the case), they're designed to evolve.
The benefit to an imperfect replication system is two-fold: 1) It allows for flexibility and versatility. 2) It serves to control reproductive fitness by reducing it. The reason why genomes are *designed* is because they contain complex specified information (I mean by this the various sequence motifs) that natural processes alone cannot produce. Unfortunately, folks like Joe Felsenstein are in abject denial about this.
Right. Reduced fitness is a benefit and biological systems were intellignetly designed to fall apart but can nevcer get any better. Got it. Time for another dump.

Atheistoclast · 22 March 2012

DS said: Right. Reduced fitness is a benefit and biological systems were intellignetly designed to fall apart but can never get any better. Got it.
Reduced fitness prevents populations from outgrowing to the point where they deplete their own resources. It is good that some of us should suffer from infertility problems because this is Nature's way of telling us that our population growth must be constrained. Once again, you show complete ignorance and a lack of intelligence.

Just Bob · 22 March 2012

Atheistoclast said: Reduced fitness prevents populations from outgrowing to the point where they deplete their own resources. It is good that some of us should suffer from infertility problems because this is Nature's way of telling us that our population growth must be constrained. Once again, you show complete ignorance and a lack of intelligence.
So our GENES know that our population shouldn't increase too fast? Yeah, right. So how is it that nearly every living thing DOES overpopulate whenever it gets the chance--like being introduced to a new environment without effective predators, or a sudden increase in food availability?

Atheistoclast · 24 March 2012

Just Bob said:
Atheistoclast said: Reduced fitness prevents populations from outgrowing to the point where they deplete their own resources. It is good that some of us should suffer from infertility problems because this is Nature's way of telling us that our population growth must be constrained. Once again, you show complete ignorance and a lack of intelligence.
So our GENES know that our population shouldn't increase too fast? Yeah, right. So how is it that nearly every living thing DOES overpopulate whenever it gets the chance--like being introduced to a new environment without effective predators, or a sudden increase in food availability?
You evidently don't know anything about zoology and population biology. Both animals and plants conserve their ecosystems by not overpopulating and depleting their resources. Of course, predation and disease (often due to mutation) help in this respect. Humans are the one species which is destroying the environment.

Just Bob · 24 March 2012

Atheistoclast said: You evidently don't know anything about zoology and population biology. Both animals and plants conserve their ecosystems by not overpopulating and depleting their resources. Of course, predation and disease (often due to mutation) help in this respect. Humans are the one species which is destroying the environment.
Just for your edification, look up recent mice plagues in Australia. Then look up the population boom-and-bust cycles of lemmings (the origin of the legends of their mass suicide). Then spend a little time with grasshoppers, and why they sometimes become locust plagues. You always pop off without really knowing what you're talking about. Must be one of your symptoms.

Scott F · 24 March 2012

The problem for astrobiologists (at least until recently) is the remote sensing of life, often with very limited dwell times. What characteristics of life might produce measurable effects in an environment that we could observe from light years away? For example, if we detected a planet with an atmosphere rich in oxygen, would that be a sure sign of life? Would lack of oxygen necessarily exclude life? Also, we might be able to make those observations only a few discrete times. Several of the characteristics so far enumerated require extended periods of observation. How might we detect life without the opportunity to directly watch a potential organism over time? Say, with a Mars rover and a few discrete samples?

Getting further afield, what if the potential organism operates on a time scale much different than ours? Maybe it has "irritability" responses measured in days or years? Would we even be able to tell?

Just some musings. :-)

Just Bob · 24 March 2012

FREE IDEA FOR AN SF WRITER!

Yes, I'm still stuck on this: A planet on which evolution stopped eons ago, due to an absolutely stable environment and no competition. Undoubtedly a very limited biota... maybe only a single species, or a couple that are commensal and interdependent. Maybe humans need that planet for something (even though it can't be Earthlike). Their activity or habitation on the planet would surely disrupt or even extinguish the indigenous species, which are utterly genetically incapable of evolving. If nothing else, they couldn't resist any introduced pathogens, or pollution, or even subtle atmospheric changes.

Would it be morally justified for humans to tamper with the planet at all? Should they try to genetically engineer adaptability back into the local species? What might be the result? Be absolutely careful not to endanger the biota in any way? Stay the hell away? Could the locals be sentient (surely not technological, but maybe with language)? What sort of past would have driven them to evolve intelligence, then cease evolving?

Paul Burnett · 24 March 2012

Just Bob said: A planet on which evolution stopped eons ago, due to an absolutely stable environment and no competition.
Passing cosmic rays would occasionally disrupt the most hardened DNA.
Undoubtedly a very limited biota... maybe only a single species, or a couple that are commensal and interdependent.
Sounds like Nivens' Puppeteers' planetary system - or even the Ringworld.

Just Bob · 24 March 2012

But there are (science fictional) cellular mechanisms to either correct or destroy any DNA (or whatever) that doesn't perfectly match the "proper" pattern.

And another conundrum for the humans: Were these organisms "designed" to remain inflexible in this static environment, and if so, by whom, and for what purpose?

dalehusband · 25 March 2012

Atheistofraud said:
DS said: Right. Reduced fitness is a benefit and biological systems were intellignetly designed to fall apart but can never get any better. Got it.
Reduced fitness prevents populations from outgrowing to the point where they deplete their own resources. It is good that some of us should suffer from infertility problems because this is Nature's way of telling us that our population growth must be constrained. Once again, you show complete ignorance and a lack of intelligence.
And you show yourself to be a pathological liar.....again!