Essays in Honor of OOS
Genetics has published three essays in honor of 150th anniversary of the Origin. Allen Orr's piece provides an interesting historical perspective on the interaction between the science of evolution (or Darwinism) and the impacts on society. The Charlesworths provide an opinion on the importance of Darwin on genetics (note that they get the D-M speciation model wrong by suggesting that it's anything but apathetic toward the role of natural selection). And Adam Wilkins weighs in on whether Darwin was a genius or a plodder.
Acknowledgement: Thanks to Richard Meisel for the blurb and the links.
Darwin and Darwinism: The (Alleged) Social Implications of The Origin of Species, by Allen Orr.
Darwin and Genetics, by Brian and Deborah Charlesworth.
Charles Darwin: Genius or Plodder?, by Adam S. Wilkins.
76 Comments
James F · 19 November 2009
What a welcome antidote to Ray Comfort's specious introduction! So happy to have an institutional subscription.
Robert Byers · 19 November 2009
There is no such thing as genius. Its just someone who did better then others who think they are pretty good.
Darwin simply had a idea that made sense to him and would hopefully put him in the ranks with Newton for great explanations.
I was surprised to find indeed Darwin meant to exclude any creation by God with the natural world or creation of man in any way.
Darwin make a concept but did not prove it.
Its not testable and so simple establishment favour has carried it forth in small circles.
Darwin is probably like Newton. He got the bigger picture wrong. His evolution is only a trivial cause and effect in nature and not the origin of anything.
Darwin still doesn't make a good case to a slight majority of people in the most intelligent nation in history.
Its been long enough and its time for Darwin to step aside.
He was wrong after all.
John Harshman · 19 November 2009
I am currently unable to interpret "the D-M speciation model". Little help here?
The article itself is behind a paywall, and the abstract doesn't even mention speciation.
John Harshman · 19 November 2009
stevaroni · 19 November 2009
fnxtr · 19 November 2009
Dan · 19 November 2009
Dan · 19 November 2009
DS · 19 November 2009
Robert wrote:
"Its been long enough and its time for Darwin to step aside. He was wrong after all."
Please, enlighten us oh sage. Exactly what do you think that Darwin was worng about? Exactly why do you care about him 150 years later if he was wrong? Exaclty why should anyone care what you think?
Joe Felsenstein · 19 November 2009
John Harshman · 19 November 2009
John Harshman · 19 November 2009
tresmal · 19 November 2009
Joe Felsenstein · 19 November 2009
Ron Okimoto · 20 November 2009
Stanton · 20 November 2009
Rich Meisel · 20 November 2009
Since I opened the D-M incompatibilities bag of worms, allow me to clarify what I meant. As Joe Felsenstein explained, the essence of the model is that allopatric populations become fixed for variants that are incompatible between the populations. For example, an ancestral population is fixed for alleles A1 and B1 at loci A & B. The population is split in two. In one population a new mutation arises at locus A (let's call it allele A2) and fixes. In the other population a mutation arises at locus B (we'll call it allele B2) and fixes. One population is fixed for A2 and B1 and the other population is fixed for A1 and B2. The A2 and B2 alleles have never been tested together, and they may be deleterious in combination. If they are deleterious, hybrids of the two populations (with the genotype A1/A2;B1/B2) will be less fit than the parental populations. If the populations are brought back into contact, this post-zygotic barrier could drive the selection for pre-zygotic barriers to reproduction which would lead to complete reproductive isolation.
My point was that the fixation of A2 and B2 in the two different populations need not be driven by natural selection. There is some evidence that natural selection does drive the fixation of these incompatibilities, but it's not necessary for the model.
Joe Felsenstein · 20 November 2009
John Harshman · 20 November 2009
But what mistake did the Charlesworths make?
I believe this is what you're talking about:
"...uncovering evidence for the Dobzhanky–Muller hypothesis that natural selection is important in causing genetic differences between populations that lower the survival or fertility of F1 or F2 hybrids, as a result of deleterious epistatic interactions between alleles derived from the two populations (e.g., Barbash et al. 2003; Presgraves et al. 2003)."
Are you saying that Dobzhansky and Muller didn't think selection was important in this process? (If so, they appear to have been wrong, but nobody is right all the time.) Or did they merely ignore the question of how those alleles became fixed? I will note that "important" isn't the same as "necessary". Drift is certainly a way to acquire divergence. But selection is faster.
Kevin (aka OgreMkV) · 20 November 2009
OK, you guys made me think, my thoughts required research and now I know something I didn't before. Thank you. However, now I have a question...
First, I'm assuming that mutation A2 or B2 only occurs in one indivual (is that valid?)
Now, if one individual has the mutation A2, in almost population of reasonable size (i.e. not 1 or 2), it is much more likely that the mutation be lost due to drift rather than fixed. The models I saw while reading all started with 50%/50% or something easy.
Correct my math here if need be. If the pop. is 100. 1 indivdual has A2, then the probability of that mutation appearing in the second generation is 1/100. So, there's a 99% chance that the mutation is lost in the next generation.
Isn't it much more likely to become fixed if there is some selection advantage?
Please forgive if I'm being dense.
Rich Meisel · 20 November 2009
Kevin, the probability of fixation of a new mutation is increased if there is a selective advantage. In a finite population, however, even most advantageous mutations will be lost. That said, as populations diverge, they will become differentiated at many loci, some fixed by neutral drift and others by natural selection.
I think the neutrality of the substitutions probably depends on the functional roles of the genes involved.
Rich Meisel · 20 November 2009
The mistake the Charlesworths made was saying that the D-M model predicts "that natural selection is important in causing genetic differences between populations". It does not such thing as far as I can tell.
John Harshman · 20 November 2009
Forgive my ignorance, as I'm not a population geneticist. But what's the reference for the D-M model? And should I suppose that this model didn't consider the reasons for fixation of incompatible alleles, and that the Charlesworths' error was in suggesting that it did?
Also, how are you Rich Meisel and Matt Young at the same time?
Rich Meisel · 20 November 2009
My take on it is that the Charlesworths were in error in suggesting that the model says anything about the reasons for fixation of the the incompatible alleles.
Here is the original paper from Dobzhanksy:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208664/
I don't think Muller's is online, but it's titled "isolating mechanisms, evolution and temperature".
Allen Orr has a nice review of it here:
http://www.ncbi.nlm.nih.gov/pubmed/8978022
John Harshman · 20 November 2009
That (Orr) was a great review. Henceforth we should call it "the Bateson model". I see your point, though Dobzhansky (as summarized by Orr) does seem to mention that fixation of the new alleles may be selectively favored. (And in fact selection would be likely to cause hybrid sterility long before neutral evolution had a chance at it.)
Joe Felsenstein · 20 November 2009
Joe Felsenstein · 20 November 2009
John Harshman · 20 November 2009
Joe, you seem to be saying that if an allelic difference is neutral in one genetic background, it must be neutral in all genetic backgrounds. And hey, let's not forget external environmental differences too.
Joe Felsenstein · 20 November 2009
John Harshman · 20 November 2009
Most of what I know about the genetics of speciation is derived from whatever the last book I read says. And the last book I read was Coyne & Orr. They mention some Drosophila studies in which there was significant isolation after many generations of population separation in identical, unchanging environments. That suggests to me that drift is capable of doing the trick, if allowed enough time.
Toidel Mahoney · 21 November 2009
Satan inspired the European Darwin to write his unholy anti-Scripture because he mistakenly believed he already controlled America when his followers in the previous century imposed on her the God-denying concept of "religious freedom" that implicitly put Sodomites on the same moral plane with Christians! The Darwiniancs shortly overran God's continent and have turned it into Satan's Kingdom of Earth.
However, godly Americans have taken Satan's tool and used it against him. The Darwinian apostles of Satan have tied their hands with their own Constitution! The can not exterminate Christians from their own land and give it to Sodomites like they did in the Old World!
Rob · 21 November 2009
Toidel Mahoney,
I have two questions for you.
1) Is God all powerful?
2) Is God unconditionally loving and ethical?
Rob
ben · 21 November 2009
Hats off to Toidel Mahoney! Whether he's a parody of a mindless creationist, or a mindless creationist, he's doing yeoman work to trash the anti-science efforts of creationists everywhere, in the minds of any sensible person who actually believes that the idiotic things he says here are representative of the movement.
DS · 21 November 2009
Toidel,
You need to have a talk with Ray Comfort. He's been spouting off about how the banana was intelligently designed to fit the human hand perfectly. Given your obsession with sodomy, perhaps there are a few things you should point out to him.
Better be careful though. I pointed out that he didn't know anything about genetics and he called me a "hateful bigot". He didn't explain what he meant or why he used those words, but in my experience , name callers are almost akways projecting their own deficiencies and shortcomings unto others.
I don't know why you think that satan was responsible for Darwin and his ideas. However, since Darwin turned out to be right, does that make satan smarter than whoever wrote the Bible?
Mike Elzinga · 21 November 2009
Toidel Mahoney · 21 November 2009
fnxtr · 21 November 2009
In addition to Rob's question, I have one for Total Baloney:
Why are you so obsessed with sodomy?
I don't think I've seen a single screed from you that didn't include some anal sex reference.
I wonder what the actual percentage of the European population actually engages in this practice, and why you want to focus so much on these individuals.
You didn't go to boarding school by any chance, did you? Or maybe you were a Catholic altar boy?
Or maybe you just wish you did?
Just wondering.
DS · 21 November 2009
Toidel wrote:
"You are making a quintessentially Darwinoid category error. You think merely because one thing is shaped like another it can be used for the same function. Those who have a teleological worldview recognize that some things are ordained by God for eating, and other things are for different purposes. A world class scientist and theologian like Comfort probably does not need me to tell him that."
Thanks for making my point. In fact, Ray is the one who made that error. He assumed that just because the banana "fits the human hand" that God designed it to be eaten. Of course, the modern banana was designed by humans and definately not designed to fit the hand, whatever that even means. As if one could not eat a banana unless it had that specific shape. What, could God not make an apple with the shape of a banana? And who is to say that God did not design the banana to be a dildo, or something? It sure has the right shape. That was the criteria Ray used was it not? If you are going to make such a blatantly stupid argueent, you should be prepared for people to point out how absurd it is.
Those with a telological view will see purpose and planning in everything. That does not mean that they can identify the planner or the purpose. They are simply imposing human motivations and desires where none are appropriate. That is the entire cruz of ID and it explains exactly nothing. Most people grow out of that kind of thinking by about ten years old. Modern society grew out of it about two hundred years ago. Of course there are always some who refuse to evolve.
Ray Comfort is not a scientist of any sort. He understands nothing of biology or genetics. Next thing he will be saying is that watermelons could not have evolved because they are seedless! Good luck with that platypus man.
harold · 21 November 2009
According to my parody versus creationist detection hypothesis, Toidel Mahoney is probably a parody poster (duh!).
Educated creationists are usually evasive and slippery, and verbose.
A slippery, evasive, verbose weasel is almost never a parody, because although such a style could easily be mimicked, doing so wouldn't be funny, or much fun.
A poster who come right out and starts firing about sodomites, hellfire, Satan, and so on may be a parody.
A poster who does that using correct spelling and grammar is almost certainly a parody.
For full disclosure, I find TM extremely amusing.
Mike Elzinga · 21 November 2009
D. P. Robin · 21 November 2009
Matt Young · 21 November 2009
DS · 21 November 2009
What about a guy who claims the following:
1) Platypus (disproves evolution don't you know)
2) Bananas (intelligently designed don't you know)
3) Genetics (you share 150% of your genes with your ancestors but genetic similarity does not mean common descent don't you know)
Could this guy possibly be serious? Would anyone take him seriously? Part of Poe's law seems to be that there is no creationist smart enough to know when everyone else thinks he is so mind-numbingly stupid that all they are doing is laughing at him. Either way, TM is sure a hoot. I hope he gets over his sodomy fetish. You really can't evolve that way.
harold · 21 November 2009
DS -
Yes, yes, yes, Anonymouse was clearly not a parodist.
It has nothing to do with the QUALITY of arguments presented. It has to do with the WAY they are presented.
He was verbose, weaselly and evasive. Look how many thousands of words he wrote. A parodist who spends hours blathering like that?
Look how he evaded every question. Look how he avoided mention of Hell, salvation, sodomites, temptresses, Judgment Day, or anything of that sort. He is only interested in creationism because it is related in his mind to those things. But rather than outright tell you that he is saved and you are going to Hell unless you repent and do what he tells you, he spends hours desperately spinning anti-science nonsense.
Verbose, weaselly and evasive = always a real creationist.
Overtly discusses Fundamentalist religious beliefs - i.e. talks about Hell, Judgment Day, Sodomy, etc = could be a parodist.
harold · 21 November 2009
Harold's Modification of Poe's Law -
Sometimes you can tell a parodist from a real creationist.
BUT the actual arguments of real creationists are, in fact, potentially as stupid or stupider than anything a parodist could come up with. In that sense, Poe's Law is correct.
It's just that sometimes there are other ways to tell the difference.
Stanton · 21 November 2009
Stanton · 21 November 2009
harold · 21 November 2009
I was laughing my head off at the "150% of genes" thing.
The context was that someone had explained that you get about 50% of your genes from each parent, and about 25% of your genes from each grandparent.
Not only did he fail to understand that we're talking about the SAME genes, and that your parents have them in common with/got them from THEIR parents (your grandparents), BUT -
He seems to think that he only has two grandparents! 2*50 + 2*25 = 150.
Stanton · 21 November 2009
Jim Thomerson · 21 November 2009
If an allopatric population is small and remains small for several generations it seems to me that genetic drift would be more likely to cause divergence than selection. Selection is a statistical phenomenon, and statistics do not work well with small populations. In a small population luck might be a more important component of fitness than genetic make up.
If two populations are allopatric, there cannot be selection for isolating mechanisms as such. If isolation mechanisms occur, they are a happenstance result of some combination of drift, selection, and whatever.
nmgirl · 21 November 2009
Stanton · 21 November 2009
Dave Luckett · 21 November 2009
Nah, Toilet's a blog troll, defined as "one who posts insults solely for the purpose of attracting attention". He doesn't really believe the crap he writes. He's just trying to get your goat, which is what trolls do. (I wonder if that's the origin of the term?) He's also a Poe - a member of the subset whose trolling consists of posing as a creationist inspired by very extreme religion.
I base this assertion on Toilet's discourse, which has subtly shifted over the couple of years I have been observing it. (Hat tip to Harold's test for Poe, which also yields this result when applied to Toilet.)
Over time, Toilet has introduced two more elements into his mix: rabid illiberalism, because most posters here are liberals in the old sense: defenders of individualism and freedom of conscience, non-authoritarians, non-traditionalists. That was always implied in the first pose; but recently we have the added pose of raging anti-Americanism, because most posters here are patriotic Americans, or at least, like me, respect and admire America at its best, and wish the best for it.
In a sense, Toilet's venom has evolved, like that of a funnelweb spider, towards greater toxicity to the prey. But he is meeting an evolutionary response: the prey is evolving resistance. Toilet is actually having trouble eliciting more than a ho-hum these days.
Therefore, I predict some new toxin will soon appear.
Toidel Mahoney · 22 November 2009
Toidel Mahoney · 22 November 2009
Constant Mews · 22 November 2009
Keelyn · 22 November 2009
fnxtr · 22 November 2009
Well I think he's pretty much run his course. Definitely Poe. Well done, TM, you had us on the run for quite a while there. Almost like JanieBell and DS. :-)
Bowser Mahoney · 22 November 2009
Matt Young · 22 November 2009
stevaroni · 22 November 2009
fnxtr · 22 November 2009
... and then later on in another part of the forest, his daughters wait until he's drunk and then jump him.
The people who believe this story are very often the same ones wailing about The Sanctity Of Marriage. Sheesh.
Shebardigan · 22 November 2009
raven · 22 November 2009
Matt G · 22 November 2009
Ravilyn.Sanders · 22 November 2009
Matt Young · 22 November 2009
Novparl · 23 November 2009
This comment has been moved to The Bathroom Wall.
Robert Byers · 23 November 2009
ben · 23 November 2009
Robert Byers · 23 November 2009
ben · 23 November 2009
Keelyn · 23 November 2009
DS · 23 November 2009
Robert tried to write:
That natural selection on mutation plus time is the origin of living organisms in the pas and today. He’s wrong. This is the hear of darwins birth or somthing they are going on about. He is the face and thoughts and gets the credit for the great error of evolution. so he is a worthy target for god guys everywhere.
yours is wrong. yous don't to know nothin. i says darwins so right for you ignorant. You's wrong in the pas and todays. This is the hear of you birth or somthin yo is goin on abouts. You is the face and thoughts of nonsenses. you will never gets credit for the great errors of you balogny. you is worthy of target on yous heads.
Do you find this agrument convincing? No? Well now you see how I feel about the shit you crapped all over. Go away Robert. You are an embaressment to fifth graders everywhere.
John Harshman · 23 November 2009
DS: That would have been so much better without the spelling error in the last sentence. Didn't you notice the dotted red line under "embaressment"?
Everyone: It's annoyingly easy for creationist trolls to hijack threads. Can't we make it a little more difficult for them? 70-some messages and only one of them on topic after the first creationist strike.
Flint · 23 November 2009