Darwin and Immunology in Science (and, Behe)
One of the better ideas I've ever been associated with was the immune system cross that Eric Rothschild put Behe through in the Kitzmiller trial in 2005. It was one of those show-your-cards moments where, finally, at long last, the ID movement's endless wild claims about the emptiness of evolutionary biology were put into direct conflict with the weight of the evidence. Everything was crystallized into a short episode -- an amazing field of research (the 100+ years of discovery about the function and origins of the immune system), an amazing practical application of evolutionary biology (both common ancestry and variation/selection played absolutely critical roles in developing science's understanding of the immune system), and a really obvious put-up-or-shut-up moment for the ID movement's "irreducible complexity" argument, where it completely failed to put up (here's a review of the ping-pong game the ID movement played with "IC systems", and how the immune system cross called their bluff).
Anyway, the cross has gotten plenty of attention and all of the details are online, but it is gratifying that Science magazine has devoted one of its "Origins" essays to the history of immunology, the role played by Darwinian ideas (both common ancestry and variation/selection), and highlights the Perry Mason immunology moment from the Kitzmiller case. It also provides an update on the science, and comprehensive links.
80 Comments
harold · 1 May 2009
It costs $15 or a trip to a library to see that Science article. I probably will do one or the other eventually.
Funny - when I was studying immunology was always fascinated by how the system might have evolved. The creationist brain is an odd thing.
Joel · 1 May 2009
"The creationist brain is an odd thing."
It is certainly a well-preserved thing.
You can tell how much they prize their intellect by the way it is so carefully rationed.
lissa · 4 May 2009
Yes, intellect is prized by creationists, because in their view it is what separates people from most other creatures.
Moses Maimonodes has written that this is what is meant by man being created in God's image.
http://en.wikipedia.org/wiki/Maimonides
I like to study philosopical things, I am not an overly religious person and I find people who try to push their own beliefs (whether they are religious beliefs, or non-religious beliefs) onto other people a bit despicable.
lissa · 4 May 2009
Stanton · 4 May 2009
lissa · 4 May 2009
DS · 4 May 2009
"So, we see that even though the immune system does undergo natural selection and survival of the fittest, just like in the animal and plant kingdoms, this is not an example of evolutionary theory in action. Natural selection and survival of the fittest actually work against differentiation through mutation… as a rule. The great varieties within “kinds” in the animal and plant kingdoms can easily be explained by “preprogrammed” or inherent genetic abilities for variety… as studied by Gregor Mendel. Similarly, the immune system has inherent abilities for genetic or preprogrammed variety… not related to the modern theory of evolution or dependent on mutation. The varieties in both worlds are dependent upon preprogrammed genetic codes, which are incredibly complicated and specific. The genetic shuffling of codes themselves follows very strict rules that are extremely complicated, but are in no way evolving beyond what are already preprogrammed and predictable changes."
Pure and utter hogwash.
Sure there are some differences between the frequencies of certain types of mutations that the specific immune response relies on and those observed in general. However, the immune response is a perfect example of a system with evolveability that undergoes random mutation and natural selection in order to produce an adaptive response, even to a novel stimulus. It is fundamentally the same as any other evolving system both in origin and in function.
Now you can ignore all of the research on the evolution and function of the immune system if you so choose, but don't expect any impartial judge to accept your ignorance as evidence of anything but your ingorance.
lissa · 4 May 2009
ps · 4 May 2009
Actually I DO know quite a bit about the immune system.
I also think that the immune system is probably preprogrammed with responses, in some cases it works improperly and it's related to genetics and DNA.
P.P.S. We share molecules in commmon with a lot of creatures that DON'T have an immune system at all also.
So what the hell DS? Let's wonder how they evolved as well. I used to be a grasshopper in a past life and my cells can prove it (lol just kidding)
Dan · 4 May 2009
lissa · 4 May 2009
ps · 4 May 2009
So which one was the lie? Do you want "proof"? people like to have "proof" that what I say is true also. Like I'm required to prove anything to them.
lol
The immune sysstem contains cells that fights threats against other cells or the entire body and also what it "perceives" as a threat to the body.
Lymph nodes contain blood cells that do this, I forgot their name, and I'm not searching the internet to write this lol. .
In the case of say a cancer happening, the genes change (they are called oncogenes specifically) and what happens is that in one stage the gene that prevents cancer stops working and a gene that causes cancer turns on. Although a healthy body should be immune to cancer.
So anyway that's about the extent of my knowledge. lol
John Kwok · 4 May 2009
lissa · 4 May 2009
Stanton · 4 May 2009
Stanton · 4 May 2009
Dan · 4 May 2009
lissa · 4 May 2009
I'm not disturbed Stanton, I'm very easy-going actually. I can take my medication appropriately, I just didn't go to my doctor to discuss it because he would have sent me to a psychiatrist, and I've avoided mental health clinics until they gave me no other alternative.
I didn't say it was your fault. And no I don't prefer to rant about it on someone else's forum, than to discuss it with my health care professionals, I just think they are a presumptuous lot of people, not that they aren't caring, but they presume too much. Like for instance, I was having a little motivation problem as well, well they "assumed" I was depressed, I wasn't it was that STUPID MEDICINE THEY WERE GIVING ME.
So sorry for the contradictory statements. I just meant my knowledge doesn't extend beyond basic knowledge the first time.
lissa · 4 May 2009
DS · 4 May 2009
lissa,
Actually I didn't call you a liar. But, since you have claimed that you are not posting as ps, I strongly suspect that you are indeed a liar.
1) Consider the perfect correlation between the threads that lissa posts on and the threads that ps posts on.
2) Consider the fact that ps respoinds to questions posed to lissa (and the reverse)
3) Consider that schizophrenia often manifested as a multiple personality disorder and lissa is admittedly under medicated
4) Consider the policy against posters using multiple names here and how rigidly it isn't enforced
lissa · 4 May 2009
I am PS DS. Is POST SCRIPT a NAME? No it's not. or would you rather have more
lissa
lissa
lissa
would that be better?
Dan · 4 May 2009
lissa · 4 May 2009
Stanton · 4 May 2009
lissa · 4 May 2009
DS · 4 May 2009
lissa,
Thanks for admitting it. I must retract my statement about you being a liar.
John Kwok · 4 May 2009
lissa · 5 May 2009
Frank J · 6 May 2009
phantomreader42 · 6 May 2009
Dean Wentworth · 6 May 2009
phantomreader42,
If the experience of a past thread is repeated, be prepared for vehemently stated claims of being quoted out-of-context and of having no interest in providing evidence, with lots of words written in all caps.
phantomreader42 · 6 May 2009
lissa · 6 May 2009
Of course not. How could I have the evidence to support it?
For 1, it happened a while ago, 2. A person cannot have evidence of what happened in their own brain/mind (even if it happened in someone else's as well) I'm not friends with the person any more, I had to cut ties with her because she was irresponsible, and put me at risk once and I did not like it. I still love her, but it was better for me to have not been around her when I made that decision.
phantomreader42 · 6 May 2009
lissa · 6 May 2009
GuyeFaux · 6 May 2009
lissa · 6 May 2009
lissa · 6 May 2009
http://www.phact.org/e/z/telepath.htm
i don't agree with this type of testing methods. I think I prefer the method they used in the video I posted where they hooked up machines to people and tested their rhythms.
That's why I thought this was pertinent to the topic. I don't think it is anything more than a physical phenomenon, I wouldn't call it a "psychic" phenomenon.
Aspect and his team discovered that under certain circumstances subatomic particles such as electrons are able to instantaneously communicate with each other regardless of the distance separating them. It doesn't matter whether they are 10 feet or 10 billion miles apart.
Somehow each particle always seems to know what the other is doing. The problem with this feat is that it violates Einstein's long-held tenet that no communication can travel faster than the speed of light. Since traveling faster than the speed of light is tantamount to breaking the time barrier, this daunting prospect has caused some physicists to try to come up with elaborate ways to explain away Aspect's findings. But it has inspired others to offer even more radical explanations
http://www.earthportals.com/hologram.html
lissa · 6 May 2009
fnxtr · 6 May 2009
Then don't expect anyone to believe you.
lissa · 6 May 2009
lissa · 6 May 2009
lissa · 6 May 2009
lissa · 6 May 2009
I think intuition plays a major role in such things as that, I think it also plays a role in some instinctual behaviors as well.
lissa · 6 May 2009
lissa · 6 May 2009
lissa · 7 May 2009
lissa · 7 May 2009
lissa · 7 May 2009
Or you could ask the lady in my group who has nightmares about her ex-husband beating on her.
You are just an ass, that's all there is to that.
fnxtr · 7 May 2009
(arms crossed over knees, rocking back and forth):
dnftt dnftt dnftt dnftt....
lissa · 7 May 2009
lissa · 7 May 2009
lissa · 7 May 2009
correction: PTSD.
lissa · 7 May 2009
Catatonia isn't a laughing matter either.
http://en.wikipedia.org/wiki/Catatonia
of course paralyzing drugs IMO should never be used to control a mental illness unless it's an emergency.
Why the hell wouldn't I go off of them anyway?
lissa · 7 May 2009
(neuroleptic malignant syndrome, toxic serotonin syndrome)
Yeah, uh-huh i have to tell them about it for a year before they decide to discontinue it though.
lissa · 7 May 2009
Stress must be reduced by not pressurising, keeping life predictable and by limiting choice as making choices is very stressful for catatonics.[citation needed]
I make choices pretty fine, but pressuring really pisses me off. That was a LOT of the problem in the first place. My mom is a nag and I told her I don't want to talk to her anymore until she learns to respect me.
Stephen Wells · 7 May 2009
Can we shift the crazy person to the Bathroom Wall now?
phantomreader42 · 7 May 2009
phantomreader42 · 7 May 2009
Dean Wentworth · 7 May 2009
Getting back to Nick Matzke's post, it is satisfying to see that Behe's humiliation on the witness stand has gotten as much publicity as it has. (Is he still insanely insisting it went well for him?)
Lately, it seems to me that, publicly at least, creationists are increasingly reluctant to attack common descent directly, focusing instead on challenging things like the big bang and abiogenesis. I see that as a retreat on their part.
lissa · 7 May 2009
John Kwok · 7 May 2009
John Kwok · 7 May 2009
Dean Wentworth · 7 May 2009
Dave Luckett · 7 May 2009
I, too, have no idea what lissa means about Darwin's beliefs. She seems to be implying that Darwin didn't believe in hell, and that was why he became an agnostic and formally renounced the Christian church. That's wrong.
He didn't believe in hell. Neither did many within the Church of England of his day - Charles Lutwidge Dodgson (Lewis Carroll), for instance. Neither do many today. But that was not what separated him from his Church and his faith. That was caused by the death of his daughter, and by his reflection that death - often painful, often lingering, often a terrifying ordeal - is designed intimately into nature itself; that it could not be the result of any human action, and had been present from the very beginning of all life. He could not reconcile the idea of an involved God, or of a loving God, with that event and those facts.
Dave Luckett · 7 May 2009
The human mind is an odd thing. I know perfectly well that death was not 'designed', but I used that word in describing its effects. It's a projection of the very type we have to combat. Please ignore it, and substitute the expression "intrinsic to nature itself" instead. Sorry.
lissa · 7 May 2009
I'm just curious. Someone being a sarcastic individual disputed that I could fly because the "sensation" of flying is not the same as flying.
What's the difference? I am me, all of me, and nothing but me.
That's the whole PRINCIPLE of HOLISTIC medicine.
Stanton · 7 May 2009
Dean Wentworth · 7 May 2009
jackstraw · 8 May 2009
Link to the cross-examination doesn't work. Timeout error.
lissa · 8 May 2009
Stanton · 8 May 2009
lissa · 8 May 2009
fnxtr · 8 May 2009
... and me without my jello nails...
lissa · 9 May 2009
lissa · 9 May 2009
lissa · 9 May 2009
I don't think any of them don't believe in a hell of some kind actually. The doctrine of "eternal damnatation" is false just because of translation problems. but that's not to say "hell" of some kind isn't believed to exist.
Dave Luckett · 9 May 2009
That's a useful link, lissa. It rightly emphasises that Darwin's beliefs, like most people's, were not fixed in concrete, nor changed only in one way. He did renounce communicant status in the Church of England, but his agnosticism fluctuated, certainly.
I think my comment is vindicated, though. He didn't believe in hell, but it was not that which separated him from his faith. That separation was caused by the death of his daughter and by the reflection that terror, suffering and pain is a necessary component of life, an ab initio precondition. He couldn't reconcile this fact with the idea of a beneficent and loving God.
lissa · 9 May 2009
lissa · 10 May 2009