In Clues To Ancestral Origin Of Placenta Emerge In Genetics Study" ScienceDaily describes the relevance of these findings:The invention of the placenta facilitated the evolution of mammals. How the placenta evolved from the simple structure observed in birds and reptiles into the complex organ that sustains human life is one of the great mysteries of evolution. By using a timecourse microarray analysis including the entire lifetime of the placenta, we uncover molecular and genomic changes that underlie placentation and find that two distinct evolutionary mechanisms were utilized during placental evolution in mice and human. Ancient genes involved in growth and metabolism were co-opted for use during early embryogenesis, likely enabling the accelerated development of extraembryonic tissues. Recently duplicated genes are utilized at later stages of placentation to meet the metabolic needs of a diverse range of pregnancy physiologies. Together, these mechanisms served to develop the specialized placenta, a novel structure that led to expansion of the eutherian mammal, including humankind.
Remind me again, how does ID explain the origin/evolution of the placenta? Sigh...The evidence suggests the placenta of humans and other mammals evolved from the much simpler tissue that attached to the inside of eggshells and enabled the embryos of our distant ancestors, the birds and reptiles, to get oxygen.
63 Comments
Henry J · 19 April 2008
PvM · 19 April 2008
Mohamed · 19 April 2008
Mohamed · 19 April 2008
Charlemage logic matches up with www.youtube.com/watch?v=FZFG5PKw504
terryf · 19 April 2008
Stanton · 19 April 2008
David Stanton · 19 April 2008
So, these same mechanisms, (gene duplication followed by divergence and then elaboration of regulatory functions and developmental pathways), hve been responsible for many novel evolutionary features, including hemoglobin, feathers, placentas, etc. The mechanisms of gene duplication are well understood and the mechanisms of divergence are well understood. We are also beginning to understand the mechnisms that allow for the evolution of gene regulation and changes in developmental pathways as well. Once again, Darwin's dangerous idea has been dramatically confirmed. Seems that the God of the gaps just keeps getting smaller and smaller.
Perhaps it would be better to embrace the science rather than whine about the supposed "moral implications". Otherwise, when the science becomes so overwhelming and undeniable, people might just remember the moral behavior of those who tried to deny the science and forget that science still can't make any moral decisions for you.
Stanton · 19 April 2008
raven · 19 April 2008
N.Wells · 19 April 2008
Stacy S. · 19 April 2008
Now that we live in pretty good shelters that keep wild animals away from our young ... can we go back to laying eggs please? :-)
Eric Finn · 19 April 2008
Stanton · 19 April 2008
Eric Finn · 19 April 2008
Stanton · 19 April 2008
Eric Finn · 19 April 2008
gabriel · 19 April 2008
Depends on the rabbit:
http://www.youtube.com/watch?v=XcxKIJTb3Hg
Perhaps a little levity will ease the tension...
Stacy S. · 19 April 2008
As a parent of an egg, I wouldn't be concerned about a bunny eating my offspring. True. Unless it were the Evil Easter Bunny.
raven · 19 April 2008
Not the first time someone has wished that humans were egg layers rather than viviparous. This thought frequently occurs in maternity wards.
There was some talk of developing an artificial womb a while ago. With advances in artificial organs and reconstructive medicine, it might be possible someday. The tissues of the placenta and the membranes are derived from the embryo, not the mother, parts of the ancient shelled egg exaptated.
My idea was to reengineer walking wombs such as cows to support human development. Embryos can sometimes be transferred between related species with successful development.
Stanton · 19 April 2008
Henry J · 19 April 2008
ungtss · 20 April 2008
From the article:
They found that the placenta develops in two distinct stages. In the first stage, which runs from the beginning of pregnancy through mid-gestation, the placental cells primarily activate genes that mammals have in common with birds and reptiles. This suggests that the placenta initially evolved through repurposing genes the early mammals inherited from their immediate ancestors when they arose more than 120 million years ago.
In the second stage, cells of the mammalian placenta switch to a new wave of species-specific genes. Mice activate newly evolved mouse genes and humans activate human genes.
For those of you interested in thinking logically, let's break this down. There are two types of ideas in this paragraph: facts, and "suggestions." The facts are that all most of the genes activated during the first stage are common to mammals, birds, and reptiles; and during the second half, mice activate genes unique to mice, and humans activate genes unique to humans.
This is science, and absolutely fascinating.
The "suggestion" is that because similar genes common to several species are activated during the first stage, they are "ancient" genes.
This is not science. It's speculation, premised on the assumption of common descent, and with absolutely no evidence, novel or otherwise, to support it.
By analogy, a hybrid vehicle and a model T both have tires made of rubber (something in common), and things not in common (the unique design of their engine). The inference to evolution is like saying, "Well, because we know that hybrids and model T's are related, we can conclude that tires are ancient and inherited by both."
That's an absurd inference.
The real challenge here is to understand how those genes came to work together in coordination -- is there a feasible stepwise pattern from "no placenta" to "protoplacenta" to "mammalian placenta?"
Not yet. Quite the contrary, it looks like there's a sudden switch from universal genes (all of which are still inexplicably coordinated) to species-species genes (all of which are also still inexplicably coordinated). Like noticing that certain elements of different computer models are shared, and certain elements are radically, uniquely, different in a highly coordinated manner.
That inference is also not science. It's an inference. It's the design inference. But it's just as reasonable, if not superior, to the alternative.
The problem with evolutionists is they take perfectly good science, and make ridiculous, unfounded proclamations of "yet more evidence than evolution." The problem's not in the science. The problem's in your interpretation thereof.
Henry J · 20 April 2008
ungtss,
Your argument presupposes that every piece of evidence has to support the whole theory all over again. There's at least a couple of problems with that approach.
1) An already established theory is supported by the totality of the relevant evidence, not any one piece thereof.
2) Once the general principles of a theory are established as being well supported by the evidence, it is quite reasonable to regard those principles as being well supported by the evidence.
Henry
Richard Simons · 20 April 2008
Shebardigan · 20 April 2008
ungtss · 20 April 2008
Shebardigan · 20 April 2008
Henry J · 20 April 2008
ungtss · 20 April 2008
Richard Simons · 20 April 2008
raven · 20 April 2008
Just skimmed this discussion. What ungtss is missing is a lot. Common descent is a fact. It was a theory at one time but that time was over a century ago.
We don't waste time reinventing the wheel each time we design a car.
The evidence is overwhelming.
1. Fossil evidence. These are tangible remains of ancient creatures that don't require theorizing to fit together. The link designating birds as avian dinosaurs was determined from a few fossils. A few more made it stronger. Then feathered dinosaurs were discovered. The hypothesis could have failed, instead it has become stronger and stronger with more data.
And contrary to the lies of the creos, we have lots of transition fossils. And more are discovered on a routine basis. Those gaps just keep getting smaller and smaller.
2. DNA evidence. When common descent was proposed in the 1800s, the mechanism of heredity was unknown. Mendel's dicovery fit right in. DNA was unknown. Nowadays, sequence analysis by machines that 2 decades ago were science fiction makes possible another test of common descent. It passed and we now use DNA sequence to determine the timing and branch points.
ID has been around in one form or another since the ancient Greeks. In >2,000 years it has gone absolutely nowhere and contributing exactly zero to science. These days it is just pseudoscience for religious fanatics from Death Cults bent on destroying the USA.
ungtss · 20 April 2008
ungtss · 20 April 2008
Henry J · 20 April 2008
ungtss · 20 April 2008
ungtss · 20 April 2008
Henry J · 20 April 2008
A. White · 21 April 2008
ungtss -
I am not a biologist or scientist of any sort, but even I can spot the flaws in using convergent evolution to try to break biological nested hierarchies. I suspect you could too, if you just allowed yourself to think about it a little more.
Let's take your example of wings. If a bat had feathered wings structured like a bird's, then you'd have a good point and this would be a clear violation of the nested hierarchy predicted by evolution. That's not the case, however. First, bat wings aren't feathered. Second, if you look at the structure of a bat's wing, you see that it's clearly derived from the mammalian arm/foreleg primarily by elongating the finger bones. This is completely different than the bone structure of a bird's wing. In addition to comparing morphologies, you could perform genetic studies of bats and birds and their non-winged relatives to see the genetic pathways convergent evolution took. Again, they would be different as predicted by evolution. You can easily look all this stuff up on google. You can even see intermediates in the dinosaur to bird transition in the fossil record.
Rather than being a problem for evolution, the wing is yet another piece of evidence for it. Why do all bats have wings of one type formed by mutating the genes of their ancestors, and all birds have wings of a completely different type formed by mutating the genes of their own ancestors? Evolution explains why perfectly. All ID can say is "the designer must have wanted it that way". And yet again we see that while evolution makes predictions like nested hierarchies (that must match both morphologically and genetically) that could easily be falsified, ID is completely unfalsifiable.
AFAIK, everything I've written applies to all cases of convergent evolution. Certainly there are times when some simple mutation does result in convergent evolution in the exact same way in species that are only distantly related. Any complicated structure that has evolved more than once, though, is likely to be very different both structurally and genetically in its different incarnations. In every incarnation, however, it will be derived from structures and genes of ancestor species, not of species in other branches of the tree of life.
As I said, I am not a scientist, so hopefully if I've gotten anything wrong somone more knowledgeable will correct me.
ungtss · 21 April 2008
ungtss · 21 April 2008
raven · 21 April 2008
Torbjörn Larsson, OM · 21 April 2008
raven · 21 April 2008
A. White · 21 April 2008
Henry J · 21 April 2008
raven · 21 April 2008
David Stanton · 21 April 2008
Ungtss wrote:
"But that’s the point, friend. You said the groupings do not happen at the high levels I was discussing. But that’s where common descent is disputed – not at the local level. Nested hierarchies do not occur at the levels at which common descent is disputed!"
I don't knw where you got this idea from, but it is completely wrong. There is a nested hierarchy of genetic similarity that extends all the way to the deepest branches of the tree of life. In fact, that is how the early branches were first discovered. The nested hierarchy corresponds precisely to the fossil record as well. Common descent is not an assumption of this data, it is a conclusion.
Using terms like "genetic entropy" just makes you look foolish. No such thing exists.
ungtss · 21 April 2008
A. White · 21 April 2008
ungtss · 21 April 2008
David Stanton · 21 April 2008
Ungtss,
For some reason you are under the mistaken impression that classification systems are arbitrary, they are not. Cladistic analysis is based on synapomorphies (i.e. shared derived characters). This analysis yields the same nested hierarchy whether you use DNA or morphology. However, you must use characters that do not display homoplasy, (i.e. convergence or reversal), in order to construct a reliable phylogeny. That is why the hierarchy of plants, based on vascular tissue, seeds and flowers, gives exactly the same answer as the genetic hierarchy and the branching order is consistent with the fossil evidence as well. This is due to common ancestry.
As to how the characters evolve, in general different genes are used for cladistic analysis than those that are important in morphological evolution. This is for technical reasons such as avoiding complications due to selection and homoplasy. However, once a reliable phylogeny is obtained, then an examination of the molecular mechanisms responsible for morphological changes will be much easier since you will already know the sequence of changes and the timing of events based on the phylogeny. This can help to dientify the genes involved in morphological changes.
So, nested hierarchies are based on DNA and they give the same answer as hierarchies based on morphology. You can't compare the genes for making wings in insects and birds because they are not homologous and neither are the wings. Once again, you must compare structures and genes that are similar due to common ancestry, not just superficallly similar.
Of course I'm sure that Henry can explain all this as well.
David Stanaton · 21 April 2008
By the way, snakes did not "develop feet". Cladistic analysis, based on morphology and genetics, clearly shows that snakes are reptiles, which are tetrapods. Limbs evolved in the ancestors of the tetrapods. Snakes evolved from four limbed ancestors and have secondarily lost their limbs. This has occurred many times during evolution and we now know some of the molecular mechanisms responsible.
David Stanton · 21 April 2008
Nested hierarachies are not consistent with ID, since God could presumably poof any structure into any organism magically at any time. For example, why couldn't some mammals have feathers? Why couldn't some birds have milk production? Nested hierarchies are only consistent with common descent. That's why independent data sets give the same answers.
Nested hierarchies are not "criterion dependent". they are dependent on historical contingency and evolutionary history. They are dependent on the branching order in the tree of life. God is not dependent on these things. If nested hierarchies were "criterion dependent" then the answers wouldn't continually surprise us and we wouldn't have to sequence any genes to find the answers.
David Stanton · 21 April 2008
If you really want to know the mechanisms of common descent, go back and read the start of this post. The placenta is a beautiful example of how gene duplication followed by divergence can generate novel structures. It is a general pattern observed over and over again in nature.
So, genetics can can not only provide answers to questions concerning the pattern of evolution, it can also provide answers to questions concerning the process of evolution as well.
You can dismiss me as a newcomer to the conversation if you choose, but if you check you will see that I made this exact same point two days ago in the seventh post in this thread.
ungtss · 21 April 2008
ungtss · 21 April 2008
Henry J · 21 April 2008
Larry Boy · 21 April 2008
Henry J · 21 April 2008
Henry J · 21 April 2008
Richard Simons · 22 April 2008
David Stanton · 22 April 2008
Ungtss,
You seem to be under the mistaken impression that biologists are all idiots and are only out to fool you. That is incorrect and illogical. Why would any scientist care what you think?
Homology is determined based on objective criteria. With genes there are statistical tests that can be employed to determine homology. With anatomy, homologous structures must be the same structure coded for by the same genes and produced by the same developmental pathways. Homoplasy in the data is reduced by careful examination of the characters involved BEFORE the clasdistic analysis is performed. We know the mechanisms of mutation and we know the relative and absolute rates of change for molecular characters. We avoid homoplasy by choosing characters that evolve at a rate appropriate to reduce the probability of convergence and reversal. The reasoning is not circular. The nested hierarchy is the result not the assumption.
As for endogenous retroiviruses (ERVs) or SINE insertions, we also know the mechanisms of transposition. There are literally millions of insertion recognition sequences in eukaryotic genomes. The probability of shared insertions by chance alone is extremely low. There is also no known mechanism for reversal, making this the perfect character for phylogenetics. Insertions persist through speciation events, thus shared insertions are strong evidence of common descent (the alternative being that God copied the mistakes). Now here is the important point, insertions are not only shared between species, but they are shared in a particular pattern, they are found in a nested hierarchy! In fact, it is the same hierarchy that is reconstructed by gene sequences, morphological analysis and the fossil record. Check out the Talk Origins archieve on plagarized errors in the Molecular Genetics section.
The nested hierarchy is exactly what is predicted by descent with modification. It is inconsistent with the hypothesis of a designer. If you insist that it is consistent, then you must explain why the designer created exactly the pattern that would be expected from common descent and no other. Is God trying to fool you as well? If so, you better play along, you know how she gets when she's angry.
David Stanton · 22 April 2008
Henry,
Thanks for the information. Of course this is just another example of superficial convergence. If the designer was responsible, I'm sure she could have done a much better job.