Appearing next in Springfield?

Posted 14 June 2005 by

Well, not quite. I’ve been catching up on my Science reading after a lot of travel, and found this very cool little article. (“Cultivating the Third Eye,” Science, Vol 308, Issue 5724, 948, 13 May 2005)

79 Comments

a maine yankee · 14 June 2005

What a strange and wonderfully complex world we live in! How exciting it is when people use their minds to understand this world instead of obfuscating it behind claims of ignorance and theological hocus-pocus.

Maybe the ID crowd should be challenged with discoveries such as this again and again. It may be time for 'science' to set the agenda in a proactive effort. (I know it's done and has been done exceptionally well by people from Loren Eiseley to Stephan Jay Gould to Cal Zimmer.)

How does the ID crowd explain arboreal traits in humans? Why does a habitual biped (Homo sap) display evidence of brachiation adaptation? Oh, the fun we could have . . . .!

Tara Smith · 14 June 2005

How does the ID crowd explain arboreal traits in humans? Why does a habitual biped (Homo sap) display evidence of brachiation adaptation? Oh, the fun we could have . . . .!

To be fair, there are those within the ID group that accept common descent.

Nick (Matzke) · 14 June 2005

That is the weirdest thing I've seen today, and that is saying something.

Charlie Wagner · 14 June 2005

Tara,
These are the things that scientists do that makes my blood boil.

There is absolutely no empirical support for the statement "In lower vertebrates, the pineal organ had a visual role which got lost during evolution." It is nothing more than audacious speculation.

As Richard Feynman said:
"if you're doing an experiment, you should report everything that you think might make it invalid--not only what you think is right about it: other causes that could possibly explain your results; and things you thought of that you've eliminated by some other experiment, and how they worked--to make sure the other fellow can tell they have been eliminated.

Details that could throw doubt on your interpretation must be given, if you know them. You must do the best you can--if you know anything at all wrong, or possibly wrong--to explain it. If you make a theory, for example, and advertise it, or put it out, then you must also put down all the facts that disagree with it, as well as those that agree with it. There is also a more subtle problem. When you have put a lot of ideas together to make an elaborate theory, you want to make sure, when explaining what it fits, that those things it fits are not just the things that gave you the idea for the theory; but that the finished theory makes something else come out right, in addition."

They should just report their results or offer other possible explanations (of which I can think of several) instead of just letting the prevailing paradigm guide them. For shame!

Steviepinhead · 14 June 2005

Gee, Charlie, would it be too much to expect you to google the key terms of a statement before you jump in with your "audacious speculation" judgments?

The statement that the pineal gland had a photoreceptor role in lower vertebrates isn't even remotely controversial. Many studies going back to the early '80s (and probably much earlier) support this photoreceptor role for the pineal.

Even in "higher" vertebrates the pineal gland likely has a related and conserved role, serving to intergrate the light and sleep cycles.

Thrifty Gene · 14 June 2005

They should just report their results or offer other possible explanations (of which I can think of several) instead of just letting the prevailing paradigm guide them. For shame!

Other explanations, let's hear um.

'Rev Dr' Lenny Flank · 14 June 2005

These are the things that scientists do that makes my blood boil.

Nobody cares what you think, Charlie. (shrug)

Charlie Wagner · 14 June 2005

The statement that the pineal gland had a photoreceptor role in lower vertebrates isn't even remotely controversial.

— Stevie
That wasn't what I was objecting to. It was the conclusion that this "got lost due to evolution".

Other explanations, let's hear um.

— Thrifty Gene
There can be no doubt that the function of the pineal body in lower vertebrates is related to the function of the pineal body in higher vertebrates. The same genes are involved in both cases. In nature, the same genes are used over and over in many different applications across a wide range of species. This in no way supports the notion that a particular function in one form "evolved from" a similar function in a lower form or that the pineal body had a "function" in lower vertebrates that was "lost" through the process of evolution and that the pineal body is a vestigial eye.

BlastfromthePast · 14 June 2005

How does the ID crowd explain arboreal traits in humans? Why does a habitual biped (Homo sap) display evidence of brachiation adaptation? Oh, the fun we could have . . . .!

— a maine yankee
I think a very easy explanation is at hand: in cells where phenotypic eye expression is normally suppressed, that suppression is now removed. But all the genetic "information" is present chromosomally in all the cells. Very simple, I think. How does the Darwinist crowd explain this?

Raven · 14 June 2005

Nobody cares what you think, Charlie. (shrug)

Actually, I do want to ask Charlie something--Charlie, you write:

There is absolutely no empirical support for the statement "In lower vertebrates, the pineal organ had a visual role which got lost during evolution." It is nothing more than audacious speculation.

Charlie, you totally reject the idea of phylogenesis, am I correct? So it must follow that you reject abstractions such as kingdom, phylum, class, order, family, genus, and possibly species, as well as all their super- and sub-divisions, right? If not, then what do you base those abstract classifications on? I asked DaveScot the same thing once, but to my disappointment, he never responded. I am sincerely curious how one can accept abstractions, but not the principles on which they rest, or, conversely, how one can reject such abstractions in the face of the evidence. So am I correct that your objection to the quote must be to the term "vertebrates" every bit as much as to "evolution" for that reason? Now I personally object to the term "lower vertebrates", but for a different reason--the implied valuation. They're not any less well-fitted to their niche than we are to ours--I would suck at being a lamprey (so to speak).

Charlie Wagner · 14 June 2005

I think a very easy explanation is at hand: in cells where phenotypic eye expression is normally suppressed, that suppression is now removed. But all the genetic "information" is present chromosomally in all the cells. Very simple, I think.

— Blast
I agree. You are 100% correct. Evolution is all about turning genes on and turning them off. Genetic "switches" are crucial components. Genes must turn on and off in specific combinations, in a specific sequence and at specific times. The question is, who programs the switches?

Thrifty Gene · 14 June 2005

There can be no doubt that the function of the pineal body in lower vertebrates is related to the function of the pineal body in higher vertebrates. The same genes are involved in both cases. In nature, the same genes are used over and over in many different applications across a wide range of species. This in no way supports the notion that a particular function in one form "evolved from" a similar function in a lower form or that the pineal body had a "function" in lower vertebrates that was "lost" through the process of evolution and that the pineal body is a vestigial eye.

So what are your "other possible explainations"?

Arden Chatfield · 14 June 2005

I agree. You are 100% correct. Evolution is all about turning genes on and turning them off. Genetic "switches" are crucial components. Genes must turn on and off in specific combinations, in a specific sequence and at specific times. The question is, who programs the switches?

Can we guess your answer?

Charlie Wagner · 14 June 2005

Charlie, you totally reject the idea of phylogenesis, am I correct? So it must follow that you reject abstractions such as kingdom, phylum, class, order, family, genus, and possibly species, as well as all their super- and sub-divisions, right? If not, then what do you base those abstract classifications on?

— Raven
That depends on what you mean by phylogeny. It is clear that all living forms are closely related and probably had a common origin. It is clear that the same genes are used over and over in a wide variety of applications across a broad range of forms. What this means, I just don't know. It may mean that some forms "evolved" from others, but we shouldn't be too quick to make that claim based solely on the relatedness of the forms on a morphological and/or molecular level. My main issue is not that evolution has not occurred, it has. Changes have occurred in the frequencies of alleles in populations due to selection pressure. That's one definition of evolution. In addition, the forms we see today are different from those of the past, so change has occurred over time. This is another definition of evolution. What I question is the mechanism. I don't believe that random processes like mutation and selection have the power to create new, highly organized structures processes, systems and organisms. I think that at some level, intelligent input is a requirement. Not every level perhaps, but at some level. As for taxonomic relationships, clearly they are human conventions, but they have some basis in reality. On a molecular level, more similar genomes clearly implies a closer relationship and the various forms are grouped in a hierarchal structure, so these abstractions have some validity. I have no objection to the term "vertebrates" since they all share a distinct morphological similarity, which has a basis in reality. I think the classification is valid.

Lucky Wilbury · 14 June 2005

Can we guess your answer?

— Arden
You can guess, but it won't do any good. I have no answer.

bill · 14 June 2005

I don't know if I'm pleased or disappointed that Charlie W didn't invoke God in his discussion.

Playing God with frogs. Yes? Doesn't that niggle anybody?

How about this. It's all chemistry. OK, biochemistry, but chemistry nevertheless. And physics.

Yes, we, and I use the term "we" to mean humans, especially those humans who are engaged in science, are learning how to manipulate the chemistry of which we are made.

How remarkable is that! And, although I can detect Charlie's blood boiling because he has this great fear of his Lord, while I have a great raport with mine, I'm pleased with "our" progress. Should we learn to actually control the process of evolution imagine what we could become!

Suppose we could engineer our species to live on Mars in a thin, cold carbon dioxide atmosphere. Suppose we could engineer our species to be photosynthetic and immune to vacuum of space. If that could be my legacy, what a legacy it could be. We could move into the universe.

Of course, while I'm cruising the stars old Charlie would be stuck on earth fighting school boards. Your choice, bro. My God kicks your god's ass.

Nic George · 14 June 2005

Charlie Wagner wrote:

"I don't believe that random processes like mutation and selection have the power to create new, highly organized structures processes, systems and organisms."

Really? What has led you not to believe this? What piece of evidence? Can you give me some examples? Or do you simply look at organisms and get the gut feeling that they are so complicated and (apparently) finely-tuned that mutation and selection couldn't possibly have created them. If that is the case then I say your understanding of the power of evolution is what is limited as opposed to evolution itself.

"As for taxonomic relationships, clearly they are human conventions, but they have some basis in reality. On a molecular level, more similar genomes clearly implies a closer relationship and the various forms are grouped in a hierarchal structure, so these abstractions have some validity."

Taxonomy and its categories are (I think) a human creation. Species concepts might work well in simpler temperate northern hemisphere ecosystems where the distinction between species is typically clear cut. However when you start working in areas like south Western Australia, where I am from, the species concept starts to have trouble. South Western Australia has not experienced any mass extinctions from glaciers and marine inundation for hundreds of millions of years. As a result we have mega-biodiversity (a hundred 'species' per hundred square meters and a 60% turnover in species per kilometer) and very complicated evolutionary histories. For example, I am working on a group of plants spread over an area of land the size of England. The populations vary morphologically and are thought to represent different variants but these variants can be hard to tell apart. They are all considered to be one species. I have completed a molecular study that shows the genetic variation between groups of populations is higher than between different species in other parts of the world! So is it one species or several, or are they just subspecies? We see the same thing in many plant groups from Western Australia. We have a tangled mass of variants, subspecies, species, related species complexes and so forth. Are we seeing examples of populations within species genetically diversifying into variants, then into subspecies, and then into species in their own right? I think we are.

If your interested check out:

http://www.worldwidewattle.com/infogallery/utilisation/saligna.php

Nic George · 14 June 2005

Charlie Wagner wrote:

"I don't believe that random processes like mutation and selection have the power to create new, highly organized structures processes, systems and organisms."

Really? What has led you not to believe this? What piece of evidence? Can you give me some examples? Or do you simply look at organisms and get the gut feeling that they are so complicated and (apparently) finely-tuned that mutation and selection couldn't possibly have created them. If that is the case then I say your understanding of the power of evolution is what is limited as opposed to evolution itself.

"As for taxonomic relationships, clearly they are human conventions, but they have some basis in reality. On a molecular level, more similar genomes clearly implies a closer relationship and the various forms are grouped in a hierarchal structure, so these abstractions have some validity."

Taxonomy and its categories are (I think) a human creation. Species concepts might work well in simpler temperate northern hemisphere ecosystems where the distinction between species is typically clear cut. However when you start working in areas like south Western Australia, where I am from, the species concept starts to have trouble. South Western Australia has not experienced any mass extinctions from glaciers and marine inundation for hundreds of millions of years. As a result we have mega-biodiversity (a hundred 'species' per hundred square meters and a 60% turnover in species per kilometer) and very complicated evolutionary histories. For example, I am working on a group of plants spread over an area of land the size of England. The populations vary morphologically and are thought to represent different variants but these variants can be hard to tell apart. They are all considered to be one species. I have completed a molecular study that shows the genetic variation between groups of populations is higher than between different species in other parts of the world! So is it one species or several, or are they just subspecies? We see the same thing in many plant groups from Western Australia. We have a tangled mass of variants, subspecies, species, related species complexes and so forth. Are we seeing examples of populations within species genetically diversifying into variants, then into subspecies, and then into species in their own right? I think we are.

If you are interested in what I am talking about check out:

http://www.worldwidewattle.com/infogallery/utilisation/saligna.php

Nic George · 14 June 2005

Ah crud! I apologize for the multi post.

Greenman · 14 June 2005

Charlie Wagner wrote, "The question is, who programs the switches?"

Why in the f*&k do people who invoke (or suggest) an "intelligent designer" not realize that this only begs the question, "Where did the goddam designer come from?"? Crap, that's irritating! (Did you ever notice that all curse words are related to either sex/women, religion, or bodily functions? For fun, I used one of each category in this post.)

PvM · 14 June 2005

But all the genetic "information" is present chromosomally in all the cells. Very simple, I think. How does the Darwinist crowd explain this?

If you are arguing that the ur-cell contained all the information then you are mistaken. How does evolutionary theory explain this? Evolution my dear friend.

I don't believe that random processes like mutation and selection have the power to create new, highly organized structures processes, systems and organisms. I think that at some level, intelligent input is a requirement. Not every level perhaps, but at some level.

— CW
Personal disbelief is no argument Charlie...

Matt Brauer · 14 June 2005

C'mon, folks, get with the times! It's "Divine Design (DD)" now. The term "Intelligent Design" is so last year.

Bruce Thompson · 14 June 2005

Thrifty Gene asks: "So (Charlie) what are your "other possible explanations"?"

Since Charlie has not replied with specifics, maybe I can be of some assistance. I can think of another plausible explanation; We know A. Vitamin A is found in face cream to remove wrinkles B. With advancing age, there is an increase in age related eye diseases making it increasing difficult to focus on reflections in mirrors to apply vitamin A face cream. http://findarticles.com/p/articles/mi_m0CYD/is_10_37/ai_87014908?cm_ven=YPI C. The development of an additional eye would counteract visual problems in the original eyes and make it easier to focus on the reflection in the mirror to apply more vitamin A face cream. The experimental transformation of the amphibian pineal gland into an eye did not happen immediately, it took 15 days of exposure. In humans, this would require years of exposure to vitamin A face cream. The development of the third eye would occur with increasing age and become functional at the stage when it would be most useful. This is a genetically programmed gift from the designer to cater to our desire to appear young and vibrant, to allow humanity a little vanity. It is only now, at our present level of scientific understanding where we have a. vitamin A face cream, b. frogs with 3 eyes and c. the theory of intelligent design that we are able to appreciate this gift.

H. Humbert · 14 June 2005

Thank you, Charlie, for once again re-affirming that IDers have nothing beyond an argument from incredulity. I know you just can't put your finger on where or at what point evolution becomes "impossible," but dag nabbit, you just can't fathom how it could operate in toto.

As others have pointed out, your personal lack of imagination is not a flaw of the theory itself.

degustibus · 14 June 2005

"Who programs the switches?"

The Tralfamadorians. (As in "Greetings from Tralfamadore" in Sirens .....etc etc.)

Next question.

Deep Dude · 15 June 2005

Evolution is all about turning genes on and turning them off. Genetic "switches" are crucial components. Genes must turn on and off in specific combinations, in a specific sequence and at specific times. The question is, who programs the switches?

Rain is all about water precipitating. Clouds are crucial components. Areas of high humidity must form in specific places, in a specific manner, at specific temperatures, and at specific times. The question is, who operates the thunder machine?

Stuart Weinstein · 15 June 2005

Charlie writes:"That wasn't what I was objecting to. It was the conclusion that this "got lost due to evolution".

Ahhh yess... The designer giveth and the designer taketh away.

darwinfinch · 15 June 2005

CW: "These are the things that scientists do that makes my blood boil."

I couldn't avoid reading this, but it's so stupid, even for CW, that I'll deign to toss out a hope: maybe he'll explode and leave us free of his utterly unfunny idiocy.

Heinz Kiosk · 15 June 2005

I think that at some level, intelligent input is a requirement. Not every level perhaps, but at some level.

At what level? Why not at other levels? What do you mean by "level" here? What is your evidence for your answer? Do you have anything to offer beyond the belief that "evolution must be false because it isn't mentioned in the Bible but because species evolution has definitely been demonstrated on numerous occasions I need to shift the goalposts to some undefined "level" to preserve my faith" ? What evidence would convince you that your

I think...

is false?

nihilan · 15 June 2005

Charlie Wagner wrote:

That depends on what you mean by phylogeny. It is clear that all living forms are closely related and probably had a common origin. It is clear that the same genes are used over and over in a wide variety of applications across a broad range of forms. What this means, I just don't know. It may mean that some forms "evolved" from others, but we shouldn't be too quick to make that claim based solely on the relatedness of the forms on a morphological and/or molecular level. My main issue is not that evolution has not occurred, it has. Changes have occurred in the frequencies of alleles in populations due to selection pressure. That's one definition of evolution. In addition, the forms we see today are different from those of the past, so change has occurred over time. This is another definition of evolution. What I question is the mechanism. I don't believe that random processes like mutation and selection have the power to create new, highly organized structures processes, systems and organisms. I think that at some level, intelligent input is a requirement. Not every level perhaps, but at some level. As for taxonomic relationships, clearly they are human conventions, but they have some basis in reality. On a molecular level, more similar genomes clearly implies a closer relationship and the various forms are grouped in a hierarchal structure, so these abstractions have some validity. I have no objection to the term "vertebrates" since they all share a distinct morphological similarity, which has a basis in reality. I think the classification is valid.

I think you all are too hard on poor Charlie. After all he's further along in his acceptance of evolutionary theory than many. I.e. the gaps he sqeezes God into are quite small compared to a lot of "anti-darwinists". Your problem Charlie is that you fall back on supernatural causes to explain what you can't understand (whether due to an actual or percieved lack of evidence). But where does this sort of thinking leave us? Imagine if after Behe's proclamation of irreducible complexity a decade ago scientists had simply thrown up their arms in a collective "oh, God... er uh an intelligent designer, did it". We never would have figured out the pathways leading to blood-clotting, immune responses, or flagellar motion. By appealing to supernatural causes that make no specific predictions contrary to the prevailing paradigm and that cannot be falsified you bring nothing to the table. Furthermore, you are implicitly asking scientists to do something that they never will; give up.

a maine yankee · 15 June 2005

"To be fair, there are those within the ID group that accept common descent."

Is this something to do with common ancestor?

I guess that the journey out of darkness must begin somewhere.

Charlie Wagner · 15 June 2005

The question is, who operates the thunder machine?

— Deep
When I was a lad, I grew up on a farm in the Catskill Mountains in New York, near the region where Washington Irving wrote "Rip Van Winkle". I used to sit around the General store in town where the older men would assemble to share tall tales of the mountains. One day, the sky darkened and loud noises were heard in the distance. One of the old men turned to me and said "do you know what that sound is?" Well, I had read all the tales and had a very good answer for him: "Yes, sir, that's Rip Van Winkle bowling with the elves." He turned to me with a glare and then burst into laughter. "No, you damned fool, that's thunder!"

Charlie Wagner · 15 June 2005

Really? What has led you not to believe this? What piece of evidence? Can you give me some examples?

— Nic
http://www.charliewagner.com/casefor.htm Nice website! I'm going to spend some time there today.

Charlie Wagner · 15 June 2005

Why in the f*&k do people who invoke (or suggest) an "intelligent designer" not realize that this only begs the question, "Where did the goddam designer come from?"? Crap, that's irritating!

— Greenman
The problem of "First Cause", the question of "who designed the designer" has been around since the beginning of time. Here's Bertrand Russell's take on it: The First Cause Argument

Perhaps the simplest and easiest to understand is the argument of the First Cause. It is maintained that everything we see in this world has a cause, and as you go back in the chain of causes further and further you must come to a First Cause, and to that First Cause you give the name of God. That argument, I suppose, does not carry very much weight nowadays, because, in the first place, cause is not quite what it used to be. The philosophers and the men of science have got going on cause, and it has not anything like the vitality that it used to have; but apart from that, you can see that the argument that there must be a First Cause is one that cannot have any validity. I may say that when I was a young man, and was debating these questions very seriously in my mind, I for a long time accepted the argument of the First Cause, until one day, at the age of eighteen, I read John Stuart Mill's Autobiography, and I there found this sentence: "My father taught me that the question, Who made me? cannot be answered, since it immediately suggests the further question, Who made God?" That very simple sentence showed me, as I still think, the fallacy in the argument of the First Cause. If everything must have a cause, then God must have a cause. If there can be anything without a cause, it may just as well be the world as God, so that there cannot be any validity in that argument. It is exactly of the same nature as the Hindu's view, that the world rested upon an elephant, and the elephant rested upon a tortoise; and when they said, "How about the tortoise?" the Indian said, "Suppose we change the subject." The argument is really no better than that. There is no reason why the world could not have come into being without a cause; nor, on the other hand, is there any reason why it should not have always existed. There is no reason to suppose that the world had a beginning at all. The idea that things must have a beginning is really due to the poverty of our imagination. Therefore, perhaps, I need not waste any more time upon the argument about the First Cause.

Heinz Kiosk · 15 June 2005

I think you all are too hard on poor Charlie. After all he's further along in his acceptance of evolutionary theory than many. I.e. the gaps he sqeezes God into are quite small compared to a lot of "anti-darwinists".

I think he is merely repeating the official Discovery Institute dogma here. As I understand it Behe, Denton, and Dembski all acknowledge the truth of common descent. As you say they just push God into what they see as the gaps in evolutionary theory. Lots of people who claim to be ID supporters don't realise this, and come out with the "You can't tell me I'm descended from apes/pond-scum" line. Those people don't support the DI version of ID at all, AFAICS. However it is hard to tell, due the the DI's reticence on what ID actually is, except to say, "Some 'designer' (powers and motivation curiously unspecified) definitely did something, sometime, though we aren't sure what, when, how, where, or why."

Tara Smith · 15 June 2005

First--

They should just report their results or offer other possible explanations (of which I can think of several) instead of just letting the prevailing paradigm guide them. For shame!

— Charlie Wagner
They very well may have. Note this is just a brief plug in Science--the original article is in the Indian Journal of Experimental Medicine, according to Science, the May issue, but I couldn't find it on their site. So they very well may have discussed it more extensively in their discussion in the primary publication. Second,

The question is, who programs the switches?

— Charlie Wagner
Why does anyone have to "program" them? While vertebrate pineal glands are far from my field, gene regulation is one area where I actually have some experience (though, granted, in prokaryotes). There is a ridiculous amount of environmental signals that can switch genes on and off--everything from CO2 concentration, to trace organic molecules in the medium, phosphorylation or cleavage of a particular protein, etc. And different "triggers" are present for many different species, and even within different strains of the same species. For example, there is a locus in S. pyogenes called sagA/pel. On one hand, it plays a role in production of the beta-hemolysin of that organism; but it also has a regulatory function, controlling expression of several other genes (including those encoding the M protein and streptokinase). In some strains of S. pyogenes, it does this via transcriptional regulation; in others, it's a post-transcriptional modification. Additionally, the genes it seems to control are different in different strains--so in some it regulates streptokinase; in others, it doesn't seem to, for one example. So your "designer" must have "programmed" them differently, eh? Seems like a lot of busy work if he's out programming all these species and sub-species and strains with a thousand different switches, working differently even within a species. OTOH, evolution is messy--it's not surprising that groups would have evolved to have these work in a slightly different manner. Which hypothesis is better supported by the data, do you think?

Alan Jenkins · 15 June 2005

Charlie and other creationist, admit microevolution and then immediately turn around and deny macroevolution for no more reason as that admission would collapse all their religious views as to the origin of life, and in particular humans. I know. I was raised this way myself and later saw the illogic and denial involved in this type of "thinking".

Charlie Wagner · 15 June 2005

Why does anyone have to "program" them?

— Tara Smith
Interesting question. Maybe there are two levels of programming working together. There is the Evo-Devo program, which controls the development of the organism. If anything goes wrong in this program, everything gets fouled up and the organism doesn't develop the way it should. I also suspect that there is a second level of control that responds to the environment. It dynamically interacts with the various "triggers" in the local environment and modifies the responses of the switches. I think this might be what happens in such effects as antibiotic or pesticide resistance. The environment modifies the switches, turns the genes on or off, producing the "mutations" that allow the population to adapt to the new environment. The idea of a static genome which passively reacts to challenges is gradually being replaced by a picture of a more dynamic and adaptive genome which is responsive and can adapt to different stresses. This ability appears to have been built into the genome to give it wide latitude to act as a universal automaton. The "intelligence" may already be there.

Charlie Wagner · 15 June 2005

So your "designer" must have "programmed" them differently, eh? Seems like a lot of busy work if he's out programming all these species and sub-species and strains with a thousand different switches, working differently even within a species.

— Tara Smith
That's exactly the point. All of the programming doesn't have to be there from the beginning. There may be an evolutionary program, one which controls what we call "evolution" (which apparently is over) and a "developmental" program, one which acts on individual development and a third program, one that allows modifications to the other programs as a result of environmental changes.

Tara Smith · 15 June 2005

Interesting question. Maybe there are two levels of programming working together.

— Charlie Wagner
You keep asserting "levels." There was a question earlier asking you to elaborate on that. :)

There is the Evo-Devo program, which controls the development of the organism. If anything goes wrong in this program, everything gets fouled up and the organism doesn't develop the way it should.

I'd disagree that if "anything" goes wrong, "everything" gets fouled up. Certainly many things can go wrong in development, and only minor things result. But as a general statement, I'm mostly OK with what you wrote.

I also suspect that there is a second level of control that responds to the environment.

Doesn't the inital level respond to the environment as well?

It dynamically interacts with the various "triggers" in the local environment and modifies the responses of the switches. I think this might be what happens in such effects as antibiotic or pesticide resistance. The environment modifies the switches, turns the genes on or off, producing the "mutations" that allow the population to adapt to the new environment.

I'd disagree with that. In some cases, sure, chemicals in the environment cause mutations, and lead to resistance. But in many cases, the resistance is already present, even if it's a one-in-a-million organism that happens to have a mutation in some particular gene which renders them resistant to the chemical. Are you familiar with the work of Luria and Delbruck?

The idea of a static genome which passively reacts to challenges is gradually being replaced by a picture of a more dynamic and adaptive genome which is responsive and can adapt to different stresses. This ability appears to have been built into the genome to give it wide latitude to act as a universal automaton. The "intelligence" may already be there.

Again, I'd mostly agree with that--but don't see how it's any support for a designer, if the "intelligence" is already present within the organism.

That's exactly the point. All of the programming doesn't have to be there from the beginning. There may be an evolutionary program, one which controls what we call "evolution" (which apparently is over)

What do you mean, "apparently is over?" Surely you aren't saying that organisms aren't still evolving?

and a "developmental" program, one which acts on individual development and a third program, one that allows modifications to the other programs as a result of environmental changes.

While I agree that these elements are all there (an organism can obviously develop, respons to the environment, and populations will evolve), I disagree that these are some kinds of discrete "programs" that were set in place once upon a time. Why couldn't they have evolved these abilities?

nihilan · 15 June 2005

From Charlie's website:

1. Those that are the product of intelligent design: washing machine, computer, an airplane. 2. Those that are not the product of intelligent design and can be explained by random processes or known laws of physics: a waterfall, a mountain, the Grand Canyon, a tornado and an ice crystal. 3. Those that cannot be determined as above: pear tree, dog and my daughter Leslie.

You overlook one important distinction between groups 1 and 3. We know that the items in group 3 were products of a process that (a) involves differential reproduction (b) involves copying errors during reproduction (c) involves heritability of said copying errors. This creates a very important distinction from the elements of group 1.

Steverino · 15 June 2005

Not being a scientist and having nothing more than a desire as a parent who wishes his child to get the correct information/education in school...what seems clear it that ID'rs, Creationist and YEC seem to want to end the topic quickly.

By that I mean, whenever there is an information gap or something yet to be explained scientifically, the stock answer is "Designer!" It's almost as though they think we will all just go, "hhhmmmm....ok!" and we'll just pack our bags and stop researching or looking for the real reason.

Would they have felt the same way when medical science, confronted with a disease, just shrugged its shoulders and said, "hhhhmmm . . . .must be the will of the designer" and just stopped trying to find a cause and cure???

I believe they fear the final outcome. Ignore the man behind the curtain . . . ..

nihilan · 15 June 2005

I believe they fear the final outcome. Ignore the man behind the curtain . . . ..

I think they fear that there is no man behind the curtain.

tytlal · 15 June 2005

I'm sure this has been asked before:

Why did the "intelligent" designer design extinct species? What we have is a clear case of a not so intelligent designer. Although, who am I to argue with mysterious forces?

I know. They became extinct because that was in The Designer's Plan (TM). Why do we ask ANY questions if everything was designed? Where is the line drawn between designed and natural?

If one believes in Intelligent Design, just what is the definition of intelligent? I am sorry that people who advocate ID are not capable of understanding (willing?) evolution . . . last time I checked, I am just as human as they yet I have the ability to understand evolution. Why was I designed differently?

Steverino · 15 June 2005

Charlie,

"Evolutionists continually disparage intelligent design, saying that it's not science and chiding ID theorists for not publishing their work in "peer-reviewed" scientific journals. This is not true. There are hundreds, if not thousands of peer-reviewed articles that appear each year in highly regarded scientific journals that support intelligent design. "

Name one article supporting an ID theory that has been proved valid.

Charlie Wagner · 15 June 2005

Steverino quoted Charlie Wagner as follows:

"Evolutionists continually disparage intelligent design, saying that it's not science and chiding ID theorists for not publishing their work in "peer-reviewed" scientific journals. This is not true. There are hundreds, if not thousands of peer-reviewed articles that appear each year in highly regarded scientific journals that support intelligent design. "

Aha, a little evolutionist quote mining, eh? Here's the part you left out: "The support is not in the interpretation or the 'spin" but in the data itself. There are a large number of papers published each year that provide prima facie evidence that there is more to what we see than can be explained by random processes and accidental mutations such as are described by neo-darwinian theory. Unfortunately, when interpretations of the data are offered, they invariable frame their conclusions in terms of the darwinian paradigm of common descent and selection, ignoring any suggestion that these results might have intelligent or purposeful components." "Molecular motors abound in the cell. Myosin motors power muscle contraction, kinesin motors move vesicles from one end of the cell to the other, and the ribosome processes along RNA." "...all three types of rotary motor contain a central, ion-binding rotor ring that is embedded in the respective coupling membrane of the cell." STRUCTURAL BIOLOGY: Nature's Rotary Electromotors Wolfgang Junge and Nathan Nelson Science 29 April 2005: 642-644 Structure of the Rotor of the V-Type Na+-ATPase from Enterococcus hirae Takeshi Murata, Ichiro Yamato, Yoshimi Kakinuma, Andrew G. W. Leslie, and John E. Walker Science 29 April 2005: 654-659 Structure of the Rotor Ring of F-Type Na+-ATPase from Ilyobacter tartaricus Thomas Meier, Patrick Polzer, Kay Diederichs, Wolfram Welte, and Peter Dimroth Science 29 April 2005: 659-662 These molecular motors contain multiple structures and multiple processes integrated together and organized in such a way that the structures and processes not only support each other, they support the overall function of the motor. These molecular motors cannot be explained by any combination of random, unguided, or accidental processes and have clear and inescapable purpose. And purpose requires intent. To assemble these molecular motors requires insight, and insight requires intelligence. Their existence is prima facie evidence of intelligent input into living systems. If anyone believes that these systems can arise without intelligent input I would be interested in hearing alternative explanations. http://www.charliewagner.com http://enigma.charliewagner.com

Charlie Wagner · 15 June 2005

Are you familiar with the work of Luria and Delbruck?

— Tara Smith
Sure. I never met Luria but I didn't care much for Delbruck. I was put off by his condescending attitude towards the work of Barbara McClintock, who I held in high regard. Anyway, they proved that it was mutations that were responsible for resistance in bacteria, rather than contact with virus. But it certainly could have been some sort of "directed" mutation resulting from a pre-existing potntial for resistance plus an environmental trigger. My goodness, that was a year before I was born! (1943)

Surely you aren't saying that organisms aren't still evolving?

That depends on what you mean by evolution. I think for the most part it's over. I see no new structures, processes, systems or organisms emerging in the future. I do, however, see modifications occurring to existing systems. If you want to call that evolution I guess you can.

Why couldn't they have evolved these abilities?

By what mechanism? Magic? A miracle? How come machines don't bootstrap themselves into existence from the raw materials in their environment?

Charlie Wagner · 15 June 2005

I couldn't avoid reading this, but it's so stupid, even for CW, that I'll deign to toss out a hope: maybe he'll explode and leave us free of his utterly unfunny idiocy.

— Darwinfinch
Would spontaneous human combustion suffice?

Rich · 15 June 2005

Hi Charlie!
I don't share your viewpoints but I think you're entering the debate in the right manner.

You write:

"That depends on what you mean by evolution. I think for the most part it's over. I see no new structures, processes, systems or organisms emerging in the future. I do, however, see modifications occurring to existing systems. If you want to call that evolution I guess you can."

Ironically, future humans will be "intelligently designed" by there predecessors. Homo-excelsior will be optimally and intelligently designed. We might even migrate off this organic substrate into something a little more durable . . .

Charlie Wagner · 15 June 2005

Ironically, future humans will be "intelligently designed" by there predecessors. Homo-excelsior will be optimally and intelligently designed. We might even migrate off this organic substrate into something a little more durable . . .

— Rich
I tend to agree with that. We have a destiny. We're on a voyage to somewhere, that seems certain. And the next level will be built on the previous level as the future unfolds. I also believe that what we are seeing is occurring for a purpose. There must be a deeper level of explanation since this world in which we live is assembled with such a remarkable ingenuity that I cannot accept it as an incidental quirk of nature or a random, purposeless event.

Tara Smith · 15 June 2005

Sure. I never met Luria but I didn't care much for Delbruck. I was put off by his condescending attitude towards the work of Barbara McClintock, who I held in high regard. Anyway, they proved that it was mutations that were responsible for resistance in bacteria, rather than contact with virus. But it certainly could have been some sort of "directed" mutation resulting from a pre-existing potntial for resistance plus an environmental trigger.

— Charlie Wagner
Well, not quite. First off, the resistance they were measuring was resistance to the virus--a bacteriophage, to be exact. One reason they performed it was specifically because the "directed" mutation idea was so prominent at that point in time--it was thought that mutations in bacteria were induced because of exposure to a particular environment. The results of Luria & Delbruck's experiments showed that the mutations were already extant in the population--they weren't induced due to the environment. Others showed later that the environment, however, can increase the mutation rate in bacteria, but these mutations still aren't "directed."

My goodness, that was a year before I was born! (1943)

That was 6 years before my parents were born. :)

That depends on what you mean by evolution. I think for the most part it's over. I see no new structures, processes, systems or organisms emerging in the future. I do, however, see modifications occurring to existing systems. If you want to call that evolution I guess you can.

How do you define all those? What is a new "structure" or "system?" Or "process," for that matter? Are you looking for something like another Cambrian explosion? What do you think would happen in the aftermath of a nuclear holocaust--would you expect to see what you call evolution then, when all kinds of new niches have opened up?

By what mechanism? Magic? A miracle?

No--mutation + natural selection. If I give you your assumption that "intelligence" already exists within the genome, why do miracles have to be invoked?

How come machines don't bootstrap themselves into existence from the raw materials in their environment?

You mean other than the obvious, "machines don't reproduce?"

Bob Maurus · 15 June 2005

Hi Charlie,

The hurdle remains, as it always has. There is an unfounded leap from intentionally designed non-biological objects known to have been conceived and designed by humans, to the claim of intentional design of biological organisms by an unknown "other" intelligence.

To call a bacterial flagellum a "motor" does not establish its kinship with an Evinrude, in anything beyond similar function.

You make the flat statement that it absolutely could not have happened without intelligent input, and at the same time you admit to having no actual evidence - beyond your opinion - to support that claim, or any idea who or what.

How much of what is now commonplace scientific knowledge was absolutely unknown 100, 50, 10 years ago? The Intelligent Design argument depends entirely on pointing to missing pieces in the current body of Scientific knowledge. That body of knowledge grows with every passing day.

On a personal note, it's good to have you back in full form.

Bob

Steviepinhead · 15 June 2005

Hey, Charlie, I see you've recycled the whole rotor-ring quote-mining thing from previous posts. Don't I seem to remember that you were going to have to go off and "think" about the homologues to the flagellar proteins?

Has that "thought" process taken you no further than this spinning in place?
Evolution may not be dead, but the ol' "thinking" cap seems to have gone well beyond its last scheduled maintenance. Isn't the propellor on top of the beany supposed to be rotated at least once a year?

Jeff S · 15 June 2005

Not being a scientist and having nothing more than a desire as a parent who wishes his child to get the correct information/education in school . . . what seems clear it that ID'rs, Creationist and YEC seem to want to end the topic quickly.

Yeah, the entire point of this controversy is not the content of evolutionary theory. If someone came along with an interesting, viable alternative theory to evolution which had some connection to reality, you can bet there would be scientists all over it. One great example of this (in astrophysics/cosmology) occurred during the 90's. New observations showed (convincingly, repeatably) that the rate of expansion of the universe was speeding up, not slowing down. This contradicted the "accepted wisdom" of several generations of cosmologists, and pointed to the correctness of what Einstein called his "greatest mistake". In a few short years, 20th century cosmology had taken a complete about face, because that's where the evidence led. So it's a complete delusion to claim that scientists are unwilling or unable to question their assumptions in the face of conflicting evidence or ideas. (The last thing scientists want to do is agree with each other...) The root of the whole creationist/ID controversy, then, is not the content, but the process. Creationist advocates rely on a lot of deliberate deception, lies, and appeals to ignorance, almost all of which is aimed at gullible, incredulous, and otherwise un-qualified "believers" who hold numerical (and political) advantage over the actual scientists able to think critically about new ideas. What they have not done is present any convincing evidence, or any coherent, well-articulated theory for their beliefs. The acid test for spotting a reasonable scientific attitude : "If someone presented you ample, clear-cut evidence contradicting your point of view, or a theoretical framework which did a better job of predicting/explaing observed data, would you consider changing your point of view ?" The Creationist response has always been a resounding "No !!!!"

Pastor Bentonit · 15 June 2005

If anyone believes that these systems can arise without intelligent input I would be interested in hearing alternative explanations.

— Charlie Wagner
Charlie, the vast majority of biologists "believe that these systems can arise without intelligent input". "Believe" as in scientifically accept, mind you. I would wager, so do (al)most all natural scientists, in fact most scientists across the board. Start here. Then dive into this. An example of gene duplication/lateral transfer of an ATPase gene can be found here.

That depends on what you mean by evolution. I think for the most part it's over. I see no new structures, processes, systems or organisms emerging in the future. I do, however, see modifications occurring to existing systems. If you want to call that evolution I guess you can.

(my emphasis) ..."descent with modification", heard that one before? Thought so...

steve · 15 June 2005

I used to deny the obvious truths of ID. But then came that flagellar motor. What about it convinced me? On the side, in little tiny letters, the plate which says "© 4004 BC - GodCo ID Systems"

that's what I call Evidence For Design.

Paul · 15 June 2005

I think a very easy explanation is at hand: in cells where phenotypic eye expression is normally suppressed, that suppression is now removed. But all the genetic "information" is present chromosomally in all the cells. Very simple, I think. How does the Darwinist crowd explain this?

— Blastfromthepast
But if this is just a matter of every cell being able to turn into an eye, why did only the pineal gland do so and not the whole frog? Is it just coincidence that the the pineal gland did?

steve · 15 June 2005

So The Simpsons has more predictive value in biology than ID. That's pretty sweet.

steve · 15 June 2005

Vitamin A my ass. The little froggie just wished very very hard for another eye. Seems like that's how it works, according to PZ's Kreationist Komix.

Michael White · 15 June 2005

The most ridiculous thing about all of this is that ID advocates seem to think that every paper that comes out has to specifically test evolution and provide evidence for or against it. Mainstream biologists agree that evolution is supported by the evidence, but they also use it as an explanatory paradigm without questioning first principles in every single paper.

This is true of every scientific field - in physics, each paper that invokes quantum theory as an explanatory paradigm does not go on about how their specific paper is support for or against quantum theory.

Charlie's blood boiled over the fact that the authors of the paper took evolution for granted and invoked it as a possible explanation for what they observed. This is normal science - just because ID advocates have issues with the first principles of evolutionary theory doesn't mean every scientific paper invoking evolution has to argue for those first principles.

Charlie Wagner · 15 June 2005

How much of what is now commonplace scientific knowledge was absolutely unknown 100, 50, 10 years ago? The Intelligent Design argument depends entirely on pointing to missing pieces in the current body of Scientific knowledge. That body of knowledge grows with every passing day.

— Bob
I agree. That's why I wrote the following on my website:

If you mean by that, do I believe in a supernatural explanation for life, the answer is no, although I do not rule it out. Gods are invented to explain those things that we do not understand. As we learn more about the world and how it works, there are fewer mysteries to explain, and therefore less of a need for gods. I think that as time goes on, we will learn more and more about the universe and the life in it. Whether we will ever be able to completely understand it is not known at this time. For now, I will accept that there is a natural, knowable explanation for the universe and for the existence of life.

Thanks for the good wishes...

'Rev Dr' Lenny Flank · 15 June 2005

We're on a voyage to somewhere, that seems certain.

To a galaxy far, far away? No one cares what you think, Charlie.

Charlie Wagner · 15 June 2005

But if this is just a matter of every cell being able to turn into an eye, why did only the pineal gland do so and not the whole frog? Is it just coincidence that the the pineal gland did?

— Paul
Now *that* is a very interesting question. Any thoughts?

Bob Maurus · 15 June 2005

Charlie,

You said, "If you mean by that, do I believe in a supernatural explanation for life, the answer is no, although I do not rule it out."

Fair enough - I don't rule it out either. But, having said that, where to go with the insistence on intelligent input? As I've said to you in at least one earlier post, I'd personally be quite happy to find out that I was the result of extra-terrestrial tinkering, but that doesn't do anything to define the root cause. It just delays the search, which starts all over again with "who designed the extra-terrestrial Tinkerer"? Remember the Blish short story, "Surface Tension"?

So, if not BibleGod, or some other god - who, or what? It seems to me there can be no other candidate. That's the downside of postulating an Intelligent agent/input.

Guess I'm going to have to spend some more time on your website. Check mine out - www.bobmaurusdotcom Sorry about that - I was getting a wierd error message.

Charlie Wagner · 16 June 2005

But, having said that, where to go with the insistence on intelligent input?

— Bob
Intelligent input does not automatically mean a supernatural god. It just means "an intelligence greater than human." I don't see any incompatibility between intelligent input and scientific naturalism. There's the old tale about the mayfly larvae living on the bottom of the pond, whose only frame of reference is the environment in which it lives. It cannot possibly envision the world that lies beyond, or the human intelligence that inhabits that world. But when it rises to the surface and metamorphoses into a fly and enters that new world, it can never go back and tell the others what it has seen. There is absolutely no reason why there cannot be a world that is unseen to us that contains intelligences as far above humans as we are above the mayfly. I've visited your website and found it very interesting.

Flint · 16 June 2005

Charlie:

Intelligent input does not automatically mean a supernatural god. It just means "an intelligence greater than human." I don't see any incompatibility between intelligent input and scientific naturalism.

I don't see any compelling reason why this intelligence need be greater than human. Greater knowledge maybe, or more advanced technology, but I can't rule out the possibility that people can fully understand biology. This raises an interesting image: What if future humans invent a time machine capable of moving into the past only in 4-billion-year quanta. They could easily get the ball rolling by making some sort of proto-bacterium capable only of reproducing and evolving and turning it loose in the canonical primordial soup. And we would finally know where we came from, and why.

Grey Wolf · 16 June 2005

Charlie said:

Intelligent input does not automatically mean a supernatural god. It just means "an intelligence greater than human." I don't see any incompatibility between intelligent input and scientific naturalism.

Except you've already told us that evolution cannot happen without intelligent input, which immediately begs the question of how did those intelligent inputers evolve in the first place. We keep going in circles, Charlie. Part of the problem, of course, is that you don't have any evidence to stand on, or a theory, or even a reasonable hypothesis to what is, in the end, just your hope or wish of what has happened. I find particularly fascinating your claim that there is no evolution going on today. Pray tell, when did it stop? Or is it like the intelligent input, which you cannot even start to answer when it happened (never mind how or why)? Hope that helps, Grey Wolf

Bob Maurus · 16 June 2005

Charlie,

Glad you enjoyed my website.

You said, "Intelligent input does not automatically mean a supernatural god. It just means "an intelligence greater than human." I don't see any incompatibility between intelligent input and scientific naturalism."

But that still doesn't address, "I'd personally be quite happy to find out that I was the result of extra-terrestrial tinkering, but that...just delays the search, which starts all over again with "who designed the extra-terrestrial Tinkerer"?...So, if not BibleGod, or some other god - who, or what? It seems to me there can be no other candidate. That's the downside of postulating an Intelligent agent/input."

An endless pushing back of root cause avoids the issue.

Bob

Flint · 16 June 2005

But hey, I suggested a solution to this problem. All we need is a simple time machine.

Bob Maurus · 16 June 2005

Flint,

The I'mMyOwnGrandpa Theory of Evolution? Track down "Surface Tension." It's a decent Golden Age read, as I recall.

Flint · 16 June 2005

Bob,

Yep, that's a classic. Blish wrote some interesting stuff. But it's not a time machine story, only a story of how some dying spacefolk re-engineered their offspring to survive in a new environment. But no doubt they were intelligently designed.

Dave S. · 16 June 2005

But that still doesn't address, "I'd personally be quite happy to find out that I was the result of extra-terrestrial tinkering, but that . . . just delays the search, which starts all over again with "who designed the extra-terrestrial Tinkerer"? . . . An endless pushing back of root cause avoids the issue.

— Bob Maurus
It's designers ... all the way down.

a maine yankee · 16 June 2005

Probably an old essay, but one to cherish and forward.

http://www.millerandlevine.com/km/evol/design2/article.html

'Rev Dr' Lenny Flank · 16 June 2005

We keep going in circles, Charlie

Um, you'll quickly discover that this isn't unusual.

Joe Shelby · 18 June 2005

CW writes the same basic stuff...

The basic point is that we know from experience that random processes cannot result in organization, no matter how much we want to believe it. Any evolutionary mechanism that relies only on random processes and rejects intelligent input is doomed to failure no matter what clever debating tricks are used to make it seem possible.[/blockquote]

Well, a simple computer program has proved the first absolute assertion off.

The second is actually disproved by the discussion of one of the (minor) flaws of that program: evolution is not "random". It is a sequence of causal events, driven by the very laws of physics we have known for the last hundred+ years. The only thing that makes it seem random is that there are so many variables involved that we can not calculate them all. Nobody calls Natural Selection a random process. Nobody considers the mutations (whether they increase or decrease in usefulness or "complexity") a random process.

We know that energy in a molecular bond can break down or split due to other chemicals or radiation; we know that DNA sequences can reassemble themselves "incorrectly" to produce imperfect copies; we know that energy added to a system can increase the complexity of molecular bonds (proved when amino acids were once packed together in a lead shell and then quickly compressed by a gunshot -- rather than breakdown in the heat, the heat and pressure joined them into more complex peptide molecules); we know that such energy enters our world on a consistent basis (the sun) as well as an inconsistent one (meteor impacts, geothermal sources).

All of these events are perfectly natural, and can affect the life impacted by them in ways that scientists hope to be able to predict.

By saying that at point "X" such an event was not natural, but supernaturally triggered, done specifically to *cause* a particular mutation to happen, does nothing for science except say "give it up." It also goes to show that you don't *believe* that the universe exists without some particular purpose. This is not a view science can prove or disprove (as such, its irrelevant here), and also is not a view shared philosophically by most Christians (including myself).

Joseph O'Donnell · 18 June 2005

Charlie wrote

I see no new structures, processes, systems or organisms emerging in the future.

I see a minimum of two new pathogens myself. EHEC and UHEC, which in 10-20 years time will be utterly unalike from the original Escherichia coli they evolved from. They will, for all intents and purposes, be entirely new organisms with a different lifestyle than the original organism and won't even have anywhere near the same DNA (not that they do now, as many genes are being lost and they have numerous non-E. coli pathogenicity factors). As for new processes, evolution has beat you to that already by producing a novel metabolic pathway for the degradation of DDE and for the degradation of nylon. Most of your assertions don't hold a lot of weight, depending of course on how you want to shift the goalposts around with such flimsy undefined terms that you've used.

steve · 19 June 2005

Joe, here's what they're going to say about Avida: An intelligent human wrote the program, an intelligent human built the computer, therefore intelligent design was required to get these interesting, novel 'evolutions'.

Is that not the biggest misunderstanding you've ever seen?

They'll also say that Avida has nothing in common with biological evolution, but that's a less shocking misunderstanding.

Joseph O'Donnell · 19 June 2005

Yeah, I'm well aware of how they disregard those results entirely, but what I'm speaking about in my post has already happened in real nature, with real bugs and is continuing to happen :)

Henry J · 20 June 2005

Re "what I'm speaking about in my post has already happened in real nature, with real bugs and is continuing to happen"

Wonder if that's what "bugs" them?

:)