Holt on Behe in New York Times Magazine

Posted 23 February 2005 by

↗ The current version of this post is on the live site: https://pandasthumb.org/archives/2005/02/holt-on-behe-in.html

There’s an interesting piece by Jim Holt in the February 20th, 2005 issue of New York Times magazine, entitled “Unintelligent Design.”  Holt makes some interesting observations, like this one:

In mammals, for instance, the recurrent laryngeal nerve does not go directly from the cranium to the larynx, the way any competent engineer would have arranged it. Instead, it extends down the neck to the chest, loops around a lung ligament and then runs back up the neck to the larynx. In a giraffe, that means a 20-foot length of nerve where 1 foot would have done. If this is evidence of design, it would seem to be of the unintelligent variety.

He also says something quite curious about Michael Behe:

But what if the designer did not style each species individually? What if he/she/it merely fashioned the primal cell and then let evolution produce the rest, kinks and all? That is what the biologist and intelligent-design proponent Michael J. Behe has suggested. Behe says that the little protein machines in the cell are too sophisticated to have arisen by mutation — an opinion that his scientific peers overwhelmingly do not share. Whether or not he is correct, his version of intelligent design implies a curious sort of designer, one who seeded the earth with elaborately contrived protein structures and then absconded, leaving the rest to blind chance. (emphasis added)

I’m curious, Thumbers and Lurkers - do you think this is a correct statement of Behe’s views?

Thanks, Dave

90 Comments

Grey Wolf · 23 February 2005

I'm curious, Thumbers and Lurkers - do you think this is a correct statement of Behe's views?

Actually, no idea. I haven't ever read anything by him stating that, but I haven't read everything he's written. I do want to point out, however, that Behe seems to be pushing creation further and further back. From the YEC position (creation ex hinilo some 10000 years back) they went further and further until their only "peer-reviewed" publication which implied normal evolution back to the Cambrian, and now completely normal evolution going all the way back to abiogenesis. I wonder if Behe has finally admited that he has no case, and is trying to save face by attempting to fit ID into what few gaps are left? Maybe we should send a letter to YEC people to point out that Behe is no longer interested in the big tent... Hope that helps (or at least brings a smile to someone's lips) Grey Wolf

Joe McFaul · 23 February 2005

It has to be, to stay consistent with Behe's comments that he believes in natural selection and in common descent.

The only thing left to be consistent with ID and also natural selection and common descent is some now and then tinkering as the Intelligent Designer glues some flagella to the butts of some bacteria once in awhile but letting evolution take its course for the most part.

Of course there is no comment from Phillp Johnson, or anybody else at Discovery Institute if *that* is all that ID has to offer.

Russell · 23 February 2005

Well, I read Behe's book, and he (surprise, surprise!) never gets specific about how and when information was "injected" into the system, but - by process of elimination - I came to the same conclusion that Holt does.

Keanus · 23 February 2005

In the NY Times Holt wrote . . .

What if he/she/it merely fashioned the primal cell and then let evolution produce the rest, kinks and all? That is what the biologist and intelligent-design proponent Michael J. Behe has suggested. Behe says that the little protein machines in the cell are too sophisticated to have arisen by mutation . . .

I noted that in Holt's piece. But I've also noted it in Behe's public statements before. He maintains that he accepts evolution but then lists the structures that he defines as irreducibly complex. Therein lies a contradiction. Unless he posits that the great designer dips in and out, as the whim strikes him/her, creating an IC object here and then one there, but leaves the rest to evolution. That strikes me as an indefensible position, not only scientifically but also theologically. Scientifically for all the usual reasons and theologically because it presents a truly cavalier and indifferent designer, one who would draw the ire of the Consumer Product Safety Commission if he operated in the US. I plan on attending the Elizabethtown College (Pennsylvania) Conference on evolution and religion on March 1st, where Behe will speak in the morning in a "debate" with Niall Shanks. In the Q & A that follows, if I can get recognized, I plan to pose that very question.

Reed A. Cartwright · 23 February 2005

From what I've read, Behe thinks that the "information" for IC systems was "front loaded" into the "first organism" only to be expresed when it was "needed."

Russell · 23 February 2005

From what I've read, Behe thinks that the "information" for IC systems was "front loaded" into the "first organism" only to be expresed when it was "needed."

Right, that was my take. Which leads to the conclusion that the first organism contained all the genetic information for E.Coli, HIV, Homo sapiens, fungus, palm trees... This strikes me as a whole lot less credible than Santa Claus.

RPM · 23 February 2005

One beauty of Darwinism is the intellectual freedom it allows.

— Jim Holt
What is Darwinism? It would be nice if the author defined this term as he understands it. It is meaningless in the biological community and most often used by people unfamiliar with the modern state of biological research (i.e., lay-advocates of ID and creationism). Because ID attempts to fit under the umbrella of evolutionary biology, and most biologists push ID out into the rain (yeah, it's a forced metaphor), should we interpret "darwinism" to mean "those who believe in the modern synthesis?"

JP · 23 February 2005

Right, that was my take. Which leads to the conclusion that the first organism contained all the genetic information for E.Coli, HIV, Homo sapiens, fungus, palm trees . . .

At least that is a testable hypothesis.

RBH · 23 February 2005

To my recollection, Behe has proposed three different (but not mutually exclusive) views. First, he has suggested the front-loading scheme, the "primal cell" business. Second, he has suggested temporary suspensions of natural laws for subssequent interventions like gluing flagella onto bacteria (his puff of smoke remark). Third, he has at least implied special creation of humans, as when he suggested that there might be irreducibly complex differences between humans and other primates. The second, of course, rules out the potential testability of the first. I suspect that the third, the suggestion of IC differences between humans and other primates, is a sop to the troops in the pews who might become a little restless over repetitions of Behe's earlier remarks about accepting common descent:

For the record, I have no reason to doubt that the universe is the billions of years old that physicists say it is. Further, I find the idea of common descent (that all organisms share a common ancestor) fairly convincing, and have no particular reason to doubt it. Darwin's Black Box, p. 7)

Behe's alleged adherence to common descent is sometimes used by his ID colleagues to show that ID is not attempting to overthrow all of biology. In that vein, William Dembski, for example, wrote in 2002:

The most prominent design theorist, Michael Behe, is on record to holding to common descent (the evolutionary interrelatedness of all organisms back to a common ancestor).

As with the rest of his colleagues in the intelligent design creationist movement, Behe has no theory of intelligent design, but just random conjectures tossed out with no development and repeated whines about the supposed inadequacies of genuine science. RBH

Andrea Bottaro · 23 February 2005

I don't think Behe is really a front-loading proponent. Half the examples of IC in Darwin's Black Box have to deal with features that existed only in vertebrates (or at least, at the time Behe thought they did): the rearranging genes of the immune system, membrane/secreted antibodies, the complement and clotting cascades.

To postulate that precursor elements for these features were "front-loaded" billions of years ago in bacteria, with the idea that they would come together on their own by random mutation and selection at the appropriate time, would mean simply to negate the whole point of IC, i.e. that these system cannot evolve by conventional evolutionary mechanisms.

I think Behe thinks that God is a "pimp my ride" kind of guy, who shows up once in a while to spiff up the Creation with spanky new features that otherwise wouldn't be there, according to some Mysterious Master Plan.

John Wendt · 23 February 2005

Because ID attempts to fit under the umbrella of evolutionary biology, and most biologists push ID out into the rain (yeah, it's a forced metaphor), should we interpret "darwinism" to mean "those who believe in the modern synthesis?"

Considering some of Darwin's seemingly quite personal remarks in his notebooks, I suggest that "Darwinism", in its broadest sense, should be taken to mean "uncompromising materialism". This may be his most fundamental contribution.

Keanus · 23 February 2005

If Behe, indeed, argues that the DNA of life was "front-loaded", then how can he tenably argue that common descent with modification occurred? That sounds strangely as if in Behe's eyes life on Earth is not much more than a computer program whose course was pre-determined with external factors playing no role. Does that mean that the great extinctions were events in the history of life analogous to god playing war games with his toys, since the cretaceous meteorite was surely not part of the genetic plan?

And, if life was "front-loaded", there should be abundant evidence of that "front-loading" in the DNA of the most primitive organisms living today. They should contain all those genes that were turned on millennia later in another branch of the evolutionary shrub to produce the more complex and more recently evolved organisms.

Keanus · 23 February 2005

If Behe, indeed, argues that the DNA of life was "front-loaded", then how can he tenably argue that common descent with modification occurred? That sounds strangely as if in Behe's eyes life on Earth is not much more than a computer program whose course was pre-determined with external factors playing no role. Does that mean that the great extinctions were events in the history of life analogous to god playing war games with his toys, since the cretaceous meteorite was surely not part of the genetic plan?

And, if life was "front-loaded", there should be abundant evidence of that "front-loading" in the DNA of the most primitive organisms living today. They should contain all those genes that were turned on millennia later in another branch of the evolutionary shrub to produce the more complex and more recently evolved organisms.

al18267 · 23 February 2005

Well, lurkers were asked for and so here I am. (I have no problem with passive voice, if you don't like it go whine to an English teacher.)

I am fond of taking ideas to their logical conclusion, and when Behe's ideas are taken to their logical conclusion it seems that the only times the designer can design is sometime around the time of the common ancestor of prokaryotes and eukaryotes and before.

Having said this, Behe also uses blood clotting as one of his example of IC, and this certainly originated at some time considerably after the first appearance of life. At the latest this would be around the time that the phylum chordata originated (I don't really know much about the circulatory systems of non-chordates and so can't comment on their clotting mechanisms). Even though this example of a supposed "IC" system must have originated after abiogenesis, I would like to give Behe the benefit of the doubt and say that since blood clotting has been shown to be reducible that it is no longer a valid example for evaluating Behe's positions.

Without blood clotting we are left with examples of systems that have their origin at the earliest period in the history of life and so ID becomes a rather desperate, if sophisticated, version of the God of the Gaps.

RPM · 23 February 2005

Considering some of Darwin's seemingly quite personal remarks in his notebooks, I suggest that "Darwinism", in its broadest sense, should be taken to mean "uncompromising materialism". This may be his most fundamental contribution.

— John Wendt
I'm guessing you misinterpreted my quote:

Because ID attempts to fit under the umbrella of evolutionary biology, and most biologists push ID out into the rain (yeah, it's a forced metaphor), should we interpret "darwinism" to mean "those who believe in the modern synthesis?"

I was trying to come up with an interpretation of what "darwinism" means when uniformed writers use the term. They may be attempting to imply some religious devotion to a dogma (sort of like the fundamental Christian obsession with the bible). Science is not run by dogma and literal reading of a 150 year old text, so the term "darwinism" is extremely confusing to a researcher in the field of evolutionary biology. My goal was to find a synonym that we could use in order to understand what a "darwinist" really is. I concluded that "evolution" would be inappropriate, as IDist tend to believe in evolution and simply offer a shotty hypothesis for how it occurs. Because the modern synthesis (neo-Darwinian synthesis) more accurately describes the 21st century biologist's understanding of evolution than Darwin's description does, I proposed that "darwinism" most likely refers to "belief in the modern synthesis."

Bayesian Bouffant · 23 February 2005

I'm curious, Thumbers and Lurkers - do you think this is a correct statement of Behe's views?

I don't think so, but then Behe hasn't been specific or clear about when the magic occured. For example, he has admitted a willingness to believe common descent, but that can't go all the way back to a single cell because some of his alleged irreducibly complex systems make sense only for multicellular organisms (blood clotting, immune system).

Stuart Levine · 23 February 2005

It is difficult to say exactly what Behe's views really are. Behe recognizes, I think, that he is not in a position to posit the existence, now or at some earlier time, of a real intelligent designer. Thus, he resorts to attacks on the perceived weaknesses in evidence for evolution. As a consequence, his "intelligent designer" lacks any specific qualities other than that he/she/it was the intelligent designer. This causes Behe's argument to ultimately collapse.

KeithB · 23 February 2005

It sounds to me that Behe is *really* a theistic evolutionist that expects to find fingerprints. (Unlike, say, Miller.)

Unfortuneately, every fingerprint turns out to be a smudge.

Longhorm · 23 February 2005

According to Andrea, "I think Behe thinks that God is a 'pimp my ride' kind of guy, who shows up once in a while to spiff up the Creation with spanky new features that otherwise wouldn't be there, according to some Mysterious Master Plan."

Good image, Andrea.

One important thing to keep in mind: If one wants to say that the designer turned inert matter (or "nothingness") directly into a part of an organism, one runs the risk of saying something that is inconsistent with common descent. Did the designer turn inert matter (or "nothingness") directly into a new cell? Cells are organisms. So, for instance, say that Behe thinks the designer turned dust directly into the first eye. That would be at odds with the hypothesis of common descent in that eyes are comprised of cells, and cells are organisms -- at least in terms of how most scientists talk. Now bacterial flagella are not cells. So if Behe's hypothesis is that the first bacterial flagellum is the only thing that a designer turned inert matter directly into, his hypothesis would be consistent with common descent.

Another point. I still can't really figure out what Behe means by "irreducibly complex." But I think he would say that some parts of me are "irreducibly complex." And I was born by my mother. So that Behe says that something is "irreducibly complex" does not enable me to justifiably believe that a being turned inert matter (or "nothingness") directly into that thing.

Behe might respond by saying that, while I am -- or parts of me are -- "irreducibly complex," we know what proximately caused the existence of me. Bacterial flagella are "irreducibly complex," and we don't know what proximately caused the existence of the first bacterial flagella. But I thought he is saying that he knows that a designer caused the existence of the first bacterial flagellum. So what is it? Is it known what caused the first bacterial flagellum or is it not known? Maybe he would say that it is not known what proximately caused the first bacterial flagellum, but it is justifiably believed that an intelligent designer proximately caused it by using some sort of power.

But it is at least justifiably believed that the existence of the thing that Behe would identify as the first fully developed bacterial flagellum was proximately caused by cell-division; for the existence of billions and billions of organisms has been proximately caused by cell-division or sexual reproduction, and it's very doubtful that a deity or extraterrestrial turned inert matter (or "nothingness") directly into an organism in the last 4,000 years. Analogously, say I walk into my bedroom and find a crisp, new $100 dollar bill on my pillow. Let's say I don't know how it got there. I'm justified in believing that no deity or extraterrestrial put it there.

Longhorm · 23 February 2005

I posted: "...it's very doubtful that a deity or extraterrestrial turned inert matter (or 'nothingness') directly into an organism in the last 4,000 years."

Very doubtful?! It is better just to say that it didn't happen.

Frank J · 23 February 2005

I'm curious, Thumbers and Lurkers - do you think this is a correct statement of Behe's views?

— Dave Thomas
Though not worded exactly like that, it is in fact the only alternate possibility stated in such detail by Behe, or any other IDer for that matter. AIUI, Behe has since stated that he doesn't take it too seriously. H. Allen Orr's quip about human pseudogenes for chlorophyll may have been a factor, but so may be an increasing "don't ask, don't tell" policy among IDers. Despite being officially noncommittal, ID arguments increasingly hint at independent abiogenesis rather than any common descent scenario. The big tent is apparently the prime motivator. More importantly, though, Behe has not, to my knowledge, tested that or any other potential alternative hypothesis.

What is Darwinism? It would be nice if the author defined this term as he understands it. It is meaningless in the biological community and most often used by people unfamiliar with the modern state of biological research (i.e., lay-advocates of ID and creationism).

— RBH
Thank you! Unfortunately, as you know, many scientists also use it carelessly, and in doing so, supply anti-evolutionists with their best rhetorical weapon.

Pete · 23 February 2005

I posted: " . . . it's very doubtful that a deity or extraterrestrial turned inert matter (or 'nothingness') directly into an organism in the last 4,000 years." ... which s/he corrected to: Very doubtful?! It is better just to say that it didn't happen.

— Longhorn
You'd better say it didn't happen. It was six thousand years if it was a day.

Chip Poirot · 23 February 2005

No one knows what the ID view really is on evolution and what portion of it they accept or don't accept because they won't state it. So whenever you characterize a position, they can say "that's not what we say".

It's also risky for them to come out with a position on how much common descent they do/don't accept. It means making statements about the age of the world and making predictions about the relatedness of species x and y, and how to show where natural selection does and does not work. That makes the theory vulnerable.

Good theories are vulnerable and do take risks. ID refuses to.

There are other considerations as well. They don't agree. There is no unified ID theory. It's a mishmash that tries to group everything from Creationism to Orthogenesis under one umbrella.

If you really want to take a trip down the rabbit hole read some of what Wells states about common descent. He argues you can have descendant species that are born from an ancestor that cares for them, but are not really the same species and not really genetically related. They are just similar enough for the ancestor to care for the descendant. So therefore, you don't really have common descent.

Keanus · 23 February 2005

I don't know quite where to post this note, but two excellent essays appeared on-line today, one from the Boston Globe and the other from the Albuquerque Journal.

Larry Calloway writing for the Albuquerque Journal, has written a serious piece on evolution and ID with an emphasis on Ernst Mayr.

David Holahan, on the other hand, has written a very funny piece in the Boston Globe that is very, very funny, bringing in our gall bladder, the appendix, automobile recalls, and nudist beaches. Given their lack of a sense of humor, it will drive the ID promoters nuts.

plunge · 23 February 2005

Dave Thomas, shame on you! If you'd read and appreciated Ken Miller's wonderful "Find Darwin's God," you'd know that Miller quotes Behe suggesting preciselythis idea. Here's Behe:

"Suppose that nearly 4 bya the designer made the first cell, already containing all of the IR biochemical systems dicussed here and many others. (One can postulate that the designs for systems that were to be used later, such as blood clotting, were present but not "turned on." In present day organisms, plenty of genes are tured off for a while, sometimes for generations, to be turned on at a later time.)

Miller then rips this idea to pieces, pointing out first of all that such a clairavoyant cell (containing all the IR systems from creatures not to walk the earth for a billion years) would be giagantic, and that none of the bacterial ancestors of this cell show any such thing. Worse, anything that was "turned off" for this length of time would degrade into nonsense because natural selection could not discard mutational errors in unexpressed genes that made it through the usual DNA correction mechanisms.

plunge · 23 February 2005

Note, for some reason the post script told me that "sms, pl" (without the interceding comma) was "questionable content" and refused to accept my post. The "sms, pl" in question was found IN BETWEEN the phrase "organisms, plenty" (again, the comma does not appear in the text I was quoting: I had to add it in order to make my post!) This certainly seems like bizarre behavior, so I'm reporting it.

plunge · 23 February 2005

I forgot to add. The Behe quote was from page 228 of "Darwin's Black Box." Do I get a cookie for being the only poster to actually address the concerns of the OP with a diect quote from Behe showing that he had advanced that as a possibility? :) I WANT A COOKIE! :)

plunge · 23 February 2005

Final post, I swear. It's "Finding Darwin's God," not "Find Darwin's God" (sounds like a scavenger hunt!)

ts · 24 February 2005

Behe's "views" are intellectually incoherent, serving only a political/social agenda of undermining belief in evolution and "the materialist worldview". Taking them seriously enough to try to untangle them just plays into the hands of the anti-evolutionists.

Dave Thomas · 24 February 2005

Plunge, you are the Man! (Or Person, if gender specification is a problem.)

The quote you mentioned is exactly what I was looking for. (It actually starts up on page 227 of Behe's book.)

Yes, you get a Cookie!

How about a Torte instead?

Make that two tortes- a Torte, and a re-Torte.

Thanks!! Dave

PS And thanks to all for their interesting comments on this thread!

Russell · 24 February 2005

Interesting... unlike most posts here at PT, not a single ID supporter jumped in. And here's where we could really use their help to clear up what Behe REALLY posits. Why do you suppose...?

DaveScot · 25 February 2005

Actually, no idea.

— Grey Wolf
Honesty at last. Behe believes that intelligence could have worked to produce the universal common ancestor (a single celled organism) and not had a hand in anything since that point. I've said this a number of times. I've then gone on, beyond anything Behe has said, to point out that ontogenesis and phylogenesis then become equivalent processes each beginning with a single cell that is pre-programmed to unfold into specialized, organized, interdependant versions of itself in response to internal and external cues. I've further pointed out that an extant organism, amoeba dubia, has a genome 200 times larger than the human genome which seems adequate to contain enough pre-programmed information to account for the diversity we see today with little in the way of random processes needed to produce any of it so there's no question that a single-celled organism can thrive with a genome that size even when hardly any of it is actually expressed. It's the only point where design is evident IMO and all the problems that skeptics of mutation/selection point to go away with a designed LUCA. It's at least worth testing by looking for genes in extant single-celled organisms that have no business being there as they've never been used in that organism or any of its ancestors. Say a gene coding for a neurotransmitter is found in a single-celled organism...

DaveScot · 25 February 2005

Miller then rips this idea to pieces, pointing out first of all that such a clairavoyant cell (containing all the IR systems from creatures not to walk the earth for a billion years) would be giagantic

— Plunge
About the size of amoeba dubia is my guess. 670 billion base pairs. Extant and (presumably) happy. Did anyone bother to point out known c-values, and the c-value paradox, to Miller? Another interesting little factoid - the Easter Lily weighs in at 190 billion base pairs.

Grey Wolf · 25 February 2005

DaveScot said:

Honesty at last.

Yes, I know it is a change from your empty rhetoric and outright false claims. You have not yet commented on my example of increase information inside an egg, DaveScot. Neither have you designed the circuit I asked of you. Nor have you explained how your wild guess of a hypothesis can be tested and, more importantly, how can it be falsified. Or even how can something go from amoeba to dog when it's "impossible" to grow a backcone or become a bird, according to your own words. By the way, would you agree that discovering that we are but one of multiple universes would falsify your amoeba "theory" - or even Behe's and Dembki's ID? You're constantly making a fleeing forward manouvre, DaveScot. You claim impossible things, or use ridiculous claims, and when you're shown to be wrong, you disappear for a while and come back to proclaim the same stuypid ideas again and again - probably when you hope we've forgotten. Hope that helps, Grey Wolf, who is probably forgeting other questions that DaveScot can't afford to face because it would show how like science his wild guesses contain

DaveScot · 25 February 2005

[qoute=Miller goes on and]none of the bacterial ancestors of this cell show any such thing. Worse, anything that was "turned off" for this length of time would degrade into nonsense because natural selection could not discard mutational errors in unexpressed genes that made it through the usual DNA correction mechanisms.

Any particular reason that bacteria didn't evolve from an anaerobic eukaryote instead of the other way around? Any reason other than an ideological constraint that presumes that evolution always proceeds from simpler to more complex?

This is too easy. Who is this Miller guy? Obviously a low IQ individual.

And his natural selection argument is bogus. Any number of simple error-checking algorithms could kill off any imperfect copies. If a designer wanted preservation of an entire genome without alteration it's not that hard to do. Computer engineers like me do it with similar amounts of critical information so if I can do it surely whoever designed the first cell could do it too. Miller needs to learn how to think outside that dogmatic box he lives in.

DaveScot · 25 February 2005

Grey Wolf

All the information needed to turn a chicken egg into a chick is inside the egg at the outset. Duh. Are you stupid or what?

DaveScot · 25 February 2005

Grey Wolf

I've been around the block a few times and have seen your type many times before. I don't have the time or the patience to argue forever with people who won't concede a valid point to save their life.

If you think there isn't enough information in a chicken egg to construct a chicken I'm not going to argue the point with you. I'm just going to pat you on the head like I would a small child and move on to another topic where there's perhaps an adult around that wants to talk about it.

DaveScot · 25 February 2005

Grey Wolf

Falsifiability is a red herring.

A hypothesis may be, in decreasing order of preference:

1) verifiable and falsifiable
2) verifiable but not falsifiable
3) not verifiable but falsifiable
4) not verifiable and not falsifiable

Design is verifiable in a number of ways. An irrefutable proof of irreducible complexity may be presented. SETI might discover the creator. An extant organism's genome might be found containing genes that code for functional proteins that were never used or expressed in any of its line of descent but are found in other lines.

It's possible that design may not be falsifiable due to the nature of negative evidence but that doesn't matter if it is, in principle, verifiable.

I question whether it can ever be verified that mutation/selection operating in the distant past accumulated enough random mutations acted upon by natural selection to 1) turn inanimate chemicals into a living DNA-based cell and 2) turn a bacteria into a dinosaur.

Hypotheses that cannot be verified aren't useless in all cases of course, as negative evidence (failure to falsify) can become compelling, but they're certainly not preferable to those that can be verified. A verified hypothesis is the best case. A falsifiable hypothesis that has yet to be falsified is inferior.

DaveScot · 25 February 2005

Behe's "views" are intellectually incoherent

— ts
Either that or it's over your head. In the immortal words of Arthur C. Clarke (said at the considerable risk being labeled a quote-miner): "Any sufficiently advanced technology is indistinguishable from magic." DaveScot's corollary: "Any sufficiently advanced thought is indistinguishable from incoherent." Write that down.

DaveScot · 25 February 2005

Unless he posits that the great designer dips in and out, as the whim strikes him/her, creating an IC object here and then one there, but leaves the rest to evolution. That strikes me as an indefensible position, not only scientifically but also theologically.

— keanus
Indefensible? That's EXACTLY what human genetic engineers are doing AS WE SPEAK. Not only is it defensible, it's an extant process in the last decade or two! ID does not say the designer has to be perfect. What the designer had to be in that case was patient. A tweak here, a tweak there, come back in a hundred million years to see how it worked out. I've sure got a lot of good working designs out the door that way. On somewhat tighter schedules of course.

DaveScot · 25 February 2005

This strikes me as a whole lot less credible than Santa Claus.

— Russel
Yeah, but Santa Claus is a whole lot more credible than the presents evolving under the tree out of dust and floorwax.

DaveScot · 25 February 2005

That sounds strangely as if in Behe's eyes life on Earth is not much more than a computer program whose course was pre-determined with external factors playing no role. Does that mean that the great extinctions were events in the history of life analogous to god playing war games with his toys, since the cretaceous meteorite was surely not part of the genetic plan?

— Keanus
Einstein went to his grave believing in determinism. Einstein's reputed to be a pretty bright guy so I wouldn't be real quick to pooh-pooh his most cherished belief that "God does not play at dice with the universe". But just for the record, I think Einstein was an idiot savant, more or less. Determinism sucks and free will exists. Ontogenesis is certainly front-loaded. Why not phylogenesis? Nature loves a fractal. Ontogenesis and phylogenesis being governed by the same underlying process on different timescales is quite elegant. I could wax on poetic equating the first cell on the earth to a chicken embryo on an egg yolk, and humans being the reproductive organ that allows the ecosytem on the earth to spread its form to other planets, but I fear you'll make fun of me if I do. So I won't. ;-) Oh the humanity - rejected by atheists AND bible thumpers. Woe is me.

plunge · 25 February 2005

"Any particular reason that bacteria didn't evolve from an anaerobic eukaryote instead of the other way around? Any reason other than an ideological constraint that presumes that evolution always proceeds from simpler to more complex?"

Well, first of all, there is no such constraint. Plenty of structures get simpler in evolution: it's all about reproductive success after all, not complexity or simplicity. Complexity just happens to often mean some pretty good solutions to problems that simplicity can't do for you.

Second of all, I think you missed part of his objection. A cell containing all those "turned off" IC strutures with foresight for all the sorts of things modern animals would need would be a HUGE cell. And there is no evidence of any of that information having been there in any of the descendants of early life. Certainly no evidence of these monster frankenstein cells.

"This is too easy. Who is this Miller guy? Obviously a low IQ individual."

Award winning biochemist. Devout Catholic.

"And his natural selection argument is bogus. Any number of simple error-checking algorithms could kill off any imperfect copies."

So... where are they? What are they? What Miller says happens, happens in all organisms (and it's worse in RNA, because that mutates faster). If genes go unexpressed for too long, they accumulate mutations that render the information garbage.

"If a designer wanted preservation of an entire genome without alteration it's not that hard to do."

Well, sure: he could just make his magic supercell that we have no evidence of work like no cell we've ever observed in nature with a mechanism that no longer exists in any modern cell. Boy, he sure tricked us!

"Computer engineers like me do it with similar amounts of critical information so if I can do it surely whoever designed the first cell could do it too. Miller needs to learn how to think outside that dogmatic box he lives in."

You mean the box of having to stick to the actual evidence we have on how cells and mutation works instead of inventing ad hoc possibilities for which there is no evidence and are inconsistent with all known data?

The reason scientist stick to that box is that if they didn't they could explain anything simply by making up some random story then going down to the pub for a beer for the rest of the day.

bcpmoon · 25 February 2005

A tweak here, a tweak there, come back in a hundred million years to see how it worked out.

— davescot
Well, this should advance the cause of Atheism more than anything. What a concept of a negligent, could't-care-less God. Why should anybody believe in such an . . . ?

It's at least worth testing by looking for genes in extant single-celled organisms that have no business being there as they've never been used in that organism or any of its ancestors. Say a gene coding for a neurotransmitter is found in a single-celled organism . . .

— davescot
That's at least a way to start research. Anyone of the DI working on that?

If you think there isn't enough information in a chicken egg to construct a chicken I'm not going to argue the point with you.

— davescot
I do not think that that was the question. Of course, the information is enough to construct a chicken, but what about a specific chicken? If the chicken is is only caused by its genome, then clones would really be identical. But they aren't. So somewhere there is an increase in information. (Not necessarily introduced into the hereditary line, but nonetheless). That was the point.

plunge · 25 February 2005

Does DaveScot just sneak into old threads to try and have the last word so no one notices?

DaveScot · 25 February 2005

Longhorn

Explain the chicken/egg paradox of DNA/ribosome. I've said I don't care for the examples that Behe used when such a beauty is right there out in the open, unexplained, paradoxical, irreducible, and possibly the most widely studied and well understood subset of cellular machinery we know of. DNA/ribosome is a computer controlled 3-D protein milling machine capable of making all the parts required to replicate itself. The problem is that proteins are needed to replicate DNA and DNA is required to replicate proteins.

The best clutching at straws attempt to modern synthesize the paradox away I've seen is through the fantasy of an "RNA world" that existed long enough to make a DNA World then conveniently vanished without a trace.

The big problem with it is that DNA is like disk storage in a computer (slow and non-volatile) while RNA is like RAM storage (fast and volatile). Those attributes are exploited in a cell just like they are in a computer. RNA never could have persisted long enough in any credible environment to evolve. It's just too volatile.

If someone can come up with a remotely believable process whereby DNA/ribosome combination evolved without direction, including the 300 or so minimum number of interdependent complex proteins that are required for self-replication then I'll never again question any part of the mutation/selection fairy tale. Good luck.

DaveScot · 25 February 2005

Plunge writes

A cell containing all those "turned off" IC strutures with foresight for all the sorts of things modern animals would need would be a HUGE cell.

What part of amoeba dubia, an extant single celled organism, having 670 billion base pairs did you not understand?

And there is no evidence of any of that information having been there in any of the descendants of early life.

We've barely started to look.

Certainly no evidence of these monster frankenstein cells.

Ameoba dubia has a monstrous genome. It might not be the biggest, just the biggest anyone has seen yet. At 200 times the human genome it's plenty to specify all the basic proteins and body plans used by say 200 different phyla which is enough phyla to account for all the extinct and extant phyla that are known. In fact, since many proteins and bits of body plans are common even across phyla domains it's probably enough to be a lot more specific. Once you get down to groups like mammals, or frogs, most of the variation is trivial rearrangements and changes in scale rather than any real novelty.

So . . . where are they? What are they?

You're prepared to tell me with a straight face that you believe in abiogenesis without a real clue about how it could have happened and at the same time question the possibility of a simple error-checking algorithm in a cell? Ferpetesake. That's just a bit of double standard there. Google "DRAM ECC". In fact I have a patent on part of an error checking algorithm. Here ya go: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/search-bool.html&r=3&f=G&l=50&co1=AND&d=ptxt&s1=springer.INZZ.&s2=dell.ASNM.&OS=IN/springer+AND+AN/dell&RS=IN/springer+AND+AN/dell But hey, don't go letting the facts get in the way of your faith in the mutation/selection fairy tale. I don't want that on my conscience, fercrisakes. I already feel bad enough about telling my other children that Santa Claus, the Easter Bunny, and the Tooth Fairy were made up out of thin air when they might have gone another year or two before figuring it out on their own recognizance.

plunge · 25 February 2005

"What part of amoeba dubia, an extant single celled organism, having 670 billion base pairs did you not understand?"

What part of "extant" do you not understand? Plenty of modern creatures have huge genomes, but I challenge you to find a human blood clotting system hidden away in dubia, or, for that matter, any uniquely mammalian systems.

"We've barely started to look."

This is like saying that we've barely started to look for the elephant someone hid in the broom closet. It's just not there. If human blood clotting genes are smuggled around in genomes waiting for humans, why aren't they in, say, sea cucumbers anymore? You're telling me they waited around in perfect condition for a billion years, and then just magically simultaneously vanished in all other species as soon as one particular species started using them for the first time?

"You're prepared to tell me with a straight face that you believe in abiogenesis without a real clue about how it could have happened and at the same time question the possibility of a simple error-checking algorithm in a cell?"

The whole point of mutations is that they are a FAILURE of the normal error-checking, or are outside what it can correct. There simply is no error-checking system that we know which could prevent unexpressed genes from mutating at all for a billion years (and then, of course, vanish into thin air right about when we are first able to start looking). Nothing in biochemistry has that level of fidelity without some sort of mechanism for killing off mutations that break fitness (and for there to be fitness, those genes HAVE to be expressed!)

The idea that you can compare man-made solid state DRAM with checksums to the workings of a cell is a joke you are apparently playing on yourself.

DaveScot · 25 February 2005

Well, this should advance the cause of Atheism more than anything. What a concept of a negligent, could't-care-less God. Why should anybody believe in such an . . . ?

— bcpmoon
I didn't say I LIKED the trial and error designer. If I liked trial and error I'd stick with the mutation/selection fairy tale. All I said was a lot of human design gets done through trial and error, lately including GENETIC design. Don't make me have to give you a link to genetic engineering sites - things like that get SO tedious.

That's at least a way to start research. Anyone of the DI working on that?

I dunno. I hope someone will get around to it. I are just a agnostic, antagonistic retired computer engineer catching up on what I missed in biology that didn't get covered in 25 years of reading Scientific American when I wasn't busy raising hell, raising kids, or inventing better Microsoft Mousetraps. And besides, I won't join any club that would have me for member. I didn't miss a whole lot, as it turns out. Abiogenesis hasn't moved much beyond Urey-Miller and I read about that in the 1960's before I turned 10 years old. At least someone figured out Miller used a contrived environment for the early earth so even those few amino acids they got to precipitate out of the soup were bogus. That's progress in a backwards sort of way I guess.

I do not think that that was the question. Of course, the information is enough to construct a chicken, but what about a specific chicken? If the chicken is is only caused by its genome, then clones would really be identical. But they aren't. So somewhere there is an increase in information. (Not necessarily introduced into the hereditary line, but nonetheless). That was the point.

Exactly where each down feather goes down to the micrometer is trivial information. The big flight feathers go on the outside of skin on the wings. The down feathers go underneath the larger feathers. That's important and it's not a random placement. And the micrometer accurate placement of the feather information is there in the egg in any case, it's just too chaotic and unimportant to worry about. If you could somehow precisely track the brownian bumpings of the progenitor protein molecules for the feather follicles you could probably predict precisely where each would end up. There is no increase of information that I can see and there is CERTAINLY no information missing needed to create a chicken instead of some other kind of bird. I'm not saying that evolution didn't have any random factors in it. I'm saying it might not have had much in the way of important things come about from random factors. Other things we can look for along these lines are trigger events that would've spurred our ancestral megacell to diversify. Fer instance, if life had a purpose beyond anaerobic single-celled critters mucking slowly around in the water it had to create an oxidizing atmosphere to support faster metabolisms. Maybe the first trigger was a certain percentage of oxygen in the atmosphere. And then maybe because terrestrial animals have to be protected from UV radiation to survive maybe an ozone layer had to be formed before that stage of evolution was triggered. I haven't really put much thought into the possible triggers yet but I believe they're there, just no one is looking for them because they're wearing mutation/selection blinders and the thought of prescribed evolution just doesn't occur to them. Very unfortunate situation. This is what happens when ego driven dogma takes over from healthy skepticism.

DaveScot · 25 February 2005

If human blood clotting genes are smuggled around in genomes waiting for humans, why aren't they in, say, sea cucumbers anymore?

Because sea cucumbers were never intended to diversify beyond sea cucumbers. Maybe you hadn't noticed but most lines go extinct. They're evolutionary dead-ends. My pet hypothesis is that the c-value paradox is explained, at least partially, by the potential diversity that an organism possesses. Most of the fluff is in repeats of various flavors (approximate, tandem, distant, what-have-you) and what little we know about those is they're often alleles which in sexually reproducing critters is a measure of potential diversity - the more alleles the more and different recombinations that are possible. We've only just scratched the surface on our own genome, which is 200 times smaller than dubias, and you're already ruling out possibilities based on no evidence whatsoever. Amazing. With 95% of the human genome a big QUESTION MARK of unknown function, you're sitting there telling me what is and is not in an unsequenced genome 200 times larger. You're obviously pretty desperate to defend your faith. I sense you're beginning to get a glimmer of how tenuous its basis is. This is too easy. Next!

DaveScot · 25 February 2005

Some other related research that I really like (I LOVE astronomy, cosmology, and space sciences in general) that I'd like to take this opportunity to plug can be found here:

http://www.google.com/search?hl=en&q=%22galactic+habitable+zone%22

This is pulling together a truly broad range of sciences.

As some of you may know, one of the largest problems with abiogenesis is the limited amount of time between the earth's formation and the appearance of the first cell - believed to be no more than 500 million years.

And the problem just keeps getting worse and worse. The more we dig into the machinery of even the simplest cells the more complex we find out they are. Thus the amount of specified complexity that had to be generated by chemical evolution grows and grows while the amount of time for it to happen on the earth does not grow.

What the "galactic habitable zone" work attempts to do is find out how much time there was for abiogenesis to occur on another earthlike planet that formed before our planet did, how many of them there were, and the range. It's fascinating stuff. Read it. The best estimate now is that the oldest earth-like planets are no more than 4 billion years older than the earth and are in a restricted band well away from the galatic center. But there should be plenty of them. So that gives abiogenesis of carbon forms (I'm not necessarily a carbon chauvinist though) an extra 4 billion years. That's a lot more wiggle room and it's probably going to be needed because that first cell was a huge step, bigger than any other leap in the path from non-life to observed diversity today.

A problem (which I think is really humorous) with abiogenesis occuring on a different planet and seeding the earth is that some group (I forget who) worked through the numbers to figure out the odds of an earth-like planet blowing up and a microbe hitching a ride on a piece of shrapnel. The odds of that are reasonable. What they figured is essentially zero odds is any of those bits of shrapnel happening to land on our planet. So even if abiogenesis occured on another planet, odds are it would have needed to have an intelligently designed transportation to get here.

Now if any of this is new information to any of you mutation/selection faithful then I say you are not well enough informed to even be talking about the problems with origins. And that's the real problem IDers have. It's not about the Panda's Thumb. It's all about where that first cell came from 4 billion years ago. The rest of evolution is easy to believe in comparison to abiogenesis.

bcpmoon · 25 February 2005

If human blood clotting genes are smuggled around in genomes waiting for humans, why aren't they in, say, sea cucumbers anymore? You're telling me they waited around in perfect condition for a billion years, and then just magically simultaneously vanished in all other species as soon as one particular species started using them for the first time?

— plunge

Because sea cucumbers were never intended to diversify beyond sea cucumbers. Maybe you hadn't noticed but most lines go extinct.

— davescot
But this means a kind of reversed evolution: Instead of an increase in genetic information, the information had to be turned off and removed in a very specific manner to lead to all the species we see today. It is the same thing, just the other way around, so we still have the problem: How to get to those stripped down amoebas, e.g. humans? Either through a unconsciously directed process (evolution) or through ID, but on each step along the way, which would be directed evolution.

Fer instance, if life had a purpose beyond anaerobic single-celled critters mucking slowly around in the water it had to create an oxidizing atmosphere to support faster metabolisms.

A bit scary, because either there is someone on earth right now who can claim that he is the pinnacle of earth's history, since everything had to be just right to produce him (Pangloss) or well, I hope "life" does not think that there must be more to it than humans and wipes us all out, trigger-happy as it is...

Chip Poirot · 25 February 2005

Dave Scot wrote:

"Falsifiability is a red herring.

A hypothesis may be, in decreasing order of preference:

1) verifiable and falsifiable
2) verifiable but not falsifiable
3) not verifiable but falsifiable
4) not verifiable and not falsifiable"

This is pretty misleading. Falsifiability is more of a pink herring. You really can't falsify most interesting theoretical statements, at least not in historical sciences like biology or in the social sciences. There's a lot of reasons for this. I think most people recognize falsifiability is dead.

But most people also recognize that its genetically cloned twin (with a few tweaks) is quite viable: testability and discreditability. Useful and interesting theoretical statements can be subject to testability and they can therefore be discredited and compared with alternative statements.

The rest is pure hokum because "verifiability" simply means arranging facts in any order to suit your purpose and declaring your hypothesis "proved". You don't take any risks or even really worry about causal mechanisms.

Of course, it doesn't surprise me that ID proponents like verifiability and dislike testability.

RPM · 25 February 2005

With 95% of the human genome a big QUESTION MARK of unknown function, you're sitting there telling me what is and is not in an unsequenced genome 200 times larger. You're obviously pretty desperate to defend your faith. I sense you're beginning to get a glimmer of how tenuous its basis is.

— DaveScot
Your argument is that there are/were genes locked away (and conserved by some mystical force) in the ancestors of all life that were not expressed until some point in history in which they were necessary in a derived taxon. I won't get into how this goes against the very tenets of Population Genetics theory -- it seems quite obvious and I hope you can grasp that. I will point out, however, that these "protected genes" had to include a coding sequence and all necessary regulatory elements (both cis and trans). The 95% of the human genome that we cannot attribute a funtion to is not coding sequence (there are simple algorithms for detecting sequences that encode proteins), so it is absolutely irrelevent to the discussion at hand. There is active research to determine both highly contrained and rapidly evolving (interesting) mystery sequence in mammalian genomes, but these NON-CODING SEQUENCES CANNOT BE GENES WITH THE POTENTIAL TO FORM I.C. PATHWAYS BECAUSE THEY DO NOT ENCODE PROTEINS. Also, how do you explain the differences in gene density between different taxa? Most animals have about the same number of genes (10,000-30,000), but some genomes are gene dense (e.g., Fugu) while some are sparse (e.g. Mammals). Do humans have a higher potential for evolving IC systems than Fugu because of some magical sequences found in the vast gene deserts throughout the genome? It appears that you are implying so much.

plunge · 25 February 2005

"Because sea cucumbers were never intended to diversify beyond sea cucumbers."

Can you even follow a simple argument? If Behe's claim is that the ancestral cell, ancestral to all life, not just human life, had all this information ready to be switched on in particular situations, then he has to explain where it all went.

"We've only just scratched the surface on our own genome, which is 200 times smaller than dubias, and you're already ruling out possibilities based on no evidence whatsoever."

Yes: there is no evidence of Frankencell genes anywhere in the animal kingdom, and they are obviously missing in places where there is no room in genomes for them.

Andrea Bottaro · 25 February 2005

Because sea cucumbers were never intended to diversify beyond sea cucumbers.

And A. dubia was "intended" to diversify into ...? How about P. resinosa, the pine tree, (that's ~70 billion base pairs), what is that "intended" to diversify into? How about newts? (they also go for 90 billion bp genomes). These guys muts have a bright evolutionary future in front of them - their genome isa whopping 160 billion base pairs! Is your argument that anything with a big genome is meant to have one for some reason, and everything with a small genome must be just about right? Is this Goldilocks genomics you are proposing?

And the problem just keeps getting worse and worse. The more we dig into the machinery of even the simplest cells the more complex we find out they are. Thus the amount of specified complexity that had to be generated by chemical evolution grows and grows while the amount of time for it to happen on the earth does not grow.

This would be much more convincing if anyone had actually shown that anything like "complex specified information" exists in biological organisms, and tried to quantify it. To this date, CSI is about as biologically meanigful a concept as Star Wars' metaclorians levels.

ts · 26 February 2005

This is pretty misleading. Falsifiability is more of a pink herring. You really can't falsify most interesting theoretical statements, at least not in historical sciences like biology or in the social sciences. There's a lot of reasons for this. I think most people recognize falsifiability is dead.

Regardless of what "most people" might recognize, this is quite confused. The most interesting theoretical statements in biology can't be falsified because they aren't false. "falsifiable" does not mean "can be shown false", it means "of a sort that it could, a priori, be shown false". All of the most interesting theoretical statements could have been shown false, had we made observations other than the ones we did. DaveScot's "verifiable but not falsifiable" isn't just "misleading", it's unadulterated horses--t. "All crows are either black all over or not", as worthless hypothesis if ever there was one, is verified by every sighting of a crow, as worthless fact if ever there was one. The same goes for "goddidit".

But most people also recognize that its genetically cloned twin (with a few tweaks) is quite viable: testability and discreditability. Useful and interesting theoretical statements can be subject to testability and they can therefore be discredited and compared with alternative statements.

This isn't falsifiability's "genetically cloned twin (with a few tweaks)", it simply is falsifiability. Here is Popper's summary:

1. It is easy to obtain confirmations, or verifications, for nearly every theory --- if we look for confirmations. 2. Confirmations should count only if they are the result of risky predictions; that is to say, if, unenlightened by the theory in question, we should have expected an event which was incompatible with the theory --- an event which would have refuted the theory. 3. Every "good" scientific theory is a prohibition: it forbids certain things to happen. The more a theory forbids, the better it is. 4. A theory which is not refutable by any conceivable event is non-scientific. Irrefutability is not a virtue of a theory (as people often think) but a vice. 5. Every genuine test of a theory is an attempt to falsify it, or to refute it. Testability is falsifiability; but there are degrees of testability: some theories are more testable, more exposed to refutation, than others; they take, as it were, greater risks. 6. Confirming evidence should not count except when it is the result of a genuine test of the theory; and this means that it can be presented as a serious but unsuccessful attempt to falsify the theory. (I now speak in such cases of "corroborating evidence.") 7. Some genuinely testable theories, when found to be false, are still upheld by their admirers --- for example by introducing ad hoc some auxiliary assumption, or by reinterpreting the theory ad hoc in such a way that it escapes refutation. Such a procedure is always possible, but it rescues the theory from refutation only at the price of destroying, or at least lowering, its scientific status. (I later described such a rescuing operation as a "conventionalist twist" or a "conventionalist stratagem.") One can sum up all this by saying that the criterion of the scientific status of a theory is its falsifiability, or refutability, or testability.

John A. Davison · 26 February 2005

I see that DaveScot is doing a good job promoting my Prescribed Evolutionary Hypothesis soon to appear in Rivista di Biologia. Thank you Dave. I do take exception though with one thing. Einstein's premature endorsement of the PEH should not be dismissed lightly.

"Everything is determined....by forces over which we have no control. It is determined for the insect as well as for the star. Human beings, vegetables, or cosmic dust - we all dance to a mysterious tune, intoned in the distance by an invisible piper."
Albert Einstein in The Saturday Evening Post, October 26, 1929.

"Our actions should be based on the ever-present awareness that human beings in their thinking, feeling, and acting are not free but are just as causally bound as the stars in their motion."
Albert Einstein, Statement to the Spinoza Society of America, September 22, 1932.

If there were such a thing as Free Will, there would be no Darwinists and there would be no Bible-Banging fundamentalists either. Both of these conditions are obviously genetically based and I see no prospect of a genetic engineering solution anytime soon. Darwinism, like political liberalism, with which it is obviously linked, is congenital, something Gilbert and Sullivan realized before the turn of the 20th century.

"Every boy and every girl,
That is born into the world alive,
Is either a little liberal,
Or else a little conservative."
Iolanthe

John A. Davison

John A. Davison · 26 February 2005

With respect to the "Unintelligent Design" with which this thread was introduced, the reason that the laryngial nerve does what it does is because nerves like blood vessels always follow the target organ during their evolution. My Dachshund Otto, named incidentally for the greatest paleontologist that ever lived, Otto Schindewolf, and a staunch antiDarwinian as well, has very short legs due to his having the same gene that produces the human achondroplastic dwarf. His nerves and blood vessels follow wherever his legs have taken them. In all mammls and in primitive amphibians the sciatic nerve passes between the fibula and the tibia of the lower leg. In the frog these bones are fused to form a tibio-fibula and the sciatic nerve, having been so trapped, now passes through that fused bone through a hole. It is a beautiful demonstration of evolution and one that I used to delight telling my students about. So the so-called "Unintelligent Design" is not that at all but simply another demonstration that the ancestor of the giraffe had a short neck. It also would indicate that God has not had to intervene during the evolutionary sequence just as both Grasse and myself agree.

"Let us not invoke God in realities in which He no longer has to intervene. The single act of creation was enough for Him."
Pierre Grasse, page 166

Incidentally, I do not agree with Grasse on a single creation: I think a couple of dozen at a minimum.

John A. Davison

Chip Poirot · 27 February 2005

TS,

The problem with Popper is that few propositions really can in principle be shown to be false. Most interesting theoretical propositions require a ceterus paribus clause (all things held equal) and rest on probabilistic events. But the matter gets worse because few theories are just "one theory", they tend to be interlocking theories. Darwin's theory of evolution is, as Mayr points out, five separate theories. The modern synthesis combines postulates from genetics and hypothesized causal mechanisms. None of these can be confronted with a decisive test. The best that they can be is confronted with evidence and measured against the evidence. In addition, it is sometimes the case that competing theories are both not discredited and so one must pick the better of the two theories rather than reject the proposition that was clearly and convincingly shown to be false.

Research strategies seldom get rejected. They tend to advance or degenerate.

The problem of falsification is far more difficult than Popper led us to believe. That does not however imply we are led down the primrose path to Feyerabend.

Testability is not falsifiability.

On the other hand, it doesn't seem that we have any other serious disagreements.

DonkeyKong · 27 February 2005

LOL do you guys read your material?

If the design isn't intelligent because it is inefficient...

Then how would nature select for it?

Are you now changing your theory to survival of the sometimes less fit?

The theory of natural selection relies on one species having enough of a compeditive advantage over other species to survive. If this nerve could be shortened incrementally it would or would not have an advantage?

To a neutral observer this is a silly argument because you are blind to your own theory's required implications.

Its like bad mouthing your boyfriend and saying what kind of woman would sleep with you...

very silly.

John A. Davison · 27 February 2005

Nature never selected for anything. That is pure Darwinian fantasy. All evolution was emergent and driven by internal forces that had little or nothing to do with the environment. That is what the Prescribed Evolutionary Hypothesis is all about. Get used to it.

John A. Davison

John A. Davison · 27 February 2005

Nature never selected for anything. That is pure Darwinian fantasy. All evolution was emergent and driven by internal forces that had little or nothing to do with the environment. That is what the Prescribed Evolutionary Hypothesis is all about. Get used to it. It is here to stay.

John A. Davison

Ed Darrell · 27 February 2005

DK said:

If the design isn't intelligent because it is inefficient . . . Then how would nature select for it?

Nature selects the design that works. Generally those designs are modifications from the previous edition. Were an intelligence to intervene, why couldn't it back up a bit and re-engineer the entire thing, replacing inefficiencies with better design? For example, why wouldn't a designer with any intelligence re-engineer the human eye, perhaps to more closely resemble the cephalopod eye? The nerve and blood vessel connections in cephalopod eyes are much more suitable for good sight, especially over a long life, especially with a sugar-rich diet. To argue that human eyes were intentionally designed with the blood and nerve connections backward is to claim the designer goofed. Now, if nature is doing the selecting, it has no choice but to use the structures available -- the badly-wired mammalian eye in the case of humans. Or consider giraffes and hummingbirds. Hummingbirds have 14 bones in their necks, though they don't need them all for any hummingbird purpose. Giraffes have 7 bones in their necks. In order to make the giraffe neck long, the 7 bones each must grow more massive. That makes the neck long -- but it also makes the giraffe top-heavy. Giraffes have a difficult time getting a drink -- they cannot kneel down nicely. Instead they splay their forelegs to the side in an awkward sort of "push-up." Old, or ill giraffes, who don't have full strength, sometimes cannot get back up. They drown in their water holes, or they are set on by predators, or the stress causes a heart attack (another interesting side effect of the longer neck). What intelligent designer with an ounce of empathy wouldn't have given the giraffe more, smaller and lighter bones in its neck? Nature had only the seven mammalian bones to use. Massiveness was an undesired by-product, but it made a design that worked, even though it is a sub-optimal design.

John A. Davison · 28 February 2005

Nature was created somehow. I hope that is acceptable to everyone. What I want to know is exactly when, after the initial creation, did the Creator of that Nature hand over the reins to that which had already been created?

Let me answer that question with a simple one word answer - NEVER.
Nature in the guise of Natural Selection is a Darwinian fantasy. Natural Selection is now and never was a creative force. Quite the contrary, it was a conservative force only serving to stabilize the species, an inescapable conclusion reached by Reginald C. Punnett, William Bateson, Leo Berg, Robert Broom, Pierre Grasse and most recently by myself.

That is why an amateur bird watcher like myself never has any difficulty identifying every bird he has ever seen armed only with Peterson's Guide to the Birds. There is absolutely nothing in the Darwinian model that had any bearing whatsoever on the emergence of life on this planet. It is a scandal and a hoax. Get used to it folks.

As for the giraffe, the fact that it is here and thriving is sufficient explanation for the adequacy of its design and it most certainly was designed just as was every other living thing past and present.

John A. Davison

Alex Merz · 1 March 2005

DaveScott typed:
[blockquote]DNA/ribosome is a computer controlled 3-D protein milling machine[/blockquote]
No, it isn't.
[blockquote]capable of making all the parts required to replicate itself.[/blockquote]
No, it's not.

Ed Darrell · 1 March 2005

That is why an amateur bird watcher like myself never has any difficulty identifying every bird he has ever seen armed only with Peterson's Guide to the Birds. There is absolutely nothing in the Darwinian model that had any bearing whatsoever on the emergence of life on this planet. It is a scandal and a hoax. Get used to it folks.

Or, more likely, you've not been observing herring gulls -- or are they lesser black-backed gulls? -- just east of England; nor trying to distinguish jays in the eastern Rockies. Thank God! Fortunately Peterson didn't do salamander guides, and Audubon left them alone! [sarcasm mode ambiguous]

Ed Darrell · 1 March 2005

As for the giraffe, the fact that it is here and thriving is sufficient explanation for the adequacy of its design and it most certainly was designed just as was every other living thing past and present.

Adequate, certainly; optimal, no. Is intelligent design a hypothesis of a "merely adequate designer?" How does that differ from natural selection in any way? What evidence is there that the designer is only smart enough to do what the weather would do, and not smart enough to know much about design? Or is ID a hypothesis of a giraffe-hating, hummingbird-blase designer?

John A. Davison · 1 March 2005

Who are you or anyone else to say what is optimal? That is arrogant and infantile. Show me any example of Natural Selection producing anything beyond a variety or subspecies. You can't and you know it. You Darwinians are living in a fantasy world and always have been. You know all about a process that has never been observed. Your primary spokespersons are or were nothing but a bunch of sedentary intellectual zeros whose sole purpose in life was to convert the entire world to the same sort of mindless, aimless, purposeless view of a universe which they proclaim with what Pierre Grasse described as "Olympian assurance." Intelligent Design is plain as day to any rational observer. You are only to be pitied for the congenital malaise from which you so obviously suffer.

I am through screwing around with you guys. It is a waste of my time. Go right on fantasizing.

Evolution is finished. Get used to it. Until you do you are wasting your time.

"Evolution, after its last enormous effort to form the mammalian orders and man, seems to be out of breath and drowsing off. I find this metaphor a good description of the present state of evolutionary phenomena."
Pierre Grasse, page 71

John A. Davison

LilLeaguer · 1 March 2005

DaveScot said in #17941

It's [abiogensis?] the only point where design is evident IMO and all the problems that skeptics of mutation/selection point to go away with a designed LUCA [L? Universal Common Ancestor].

Is DaveScot saying that the only evidence for an ID is in the evidence for the existence of a common ancestor organism that:
  • Had a superset of all the genetic information for all existing, extinct, and future organisms
  • Furthermore had a genetic program to disperse that information into its descendants
  • Used a super-accurate copying system to ensure that the original genetic information was not transformed along the way
  • Had no ancestors itself
  • For once, I think I agree with him. Unfortunately, I am not aware of any evidence for such an organism. -LilLeaguer

    Wayne Francis · 1 March 2005

    I'm going to make a prediction against the blog troll theory based on extensive research and a large amount of data.

    I am through screwing around with you guys. It is a waste of my time. Go right on fantasizing.

    — John A. Davision
    I predict that this statement is false and that we'll still have JAD spouting his superior intellect paranoid schizophrenia dribble about how evolution no longer occurs in the face of the evidence that has been provided to him time and time again. He expects new birds species, that look radically different to their parent population, to evolve over the course of a few decades to prove evolution. As much as he keeps saying he's done with us the law of blog trolling prevents him from actually leaving just as that same law allows him to ignore any statement, data, facts, papers, etc that refute his flawed hypothesis.

    Enough · 1 March 2005

    I'd read that paper.

    Longhorm · 1 March 2005

    Dave Scott writes: "Explain the chicken/egg paradox of DNA/ribosome."

    Dave, I'm not sure I see what you mean. But maybe you want to say that the first DNA on planet earth was "irreducibly complex." But I think you would also want to say that the DNA in me is "irreducibly complex," and my DNA came into being through sexual reproduction and meiosis. So that you think something is "irreducibly complex" does not enable us to justifiably believe that a deity or extraterrestrial turned inert matter (or "nothingness") -- poof! -- directly into that thing.

    I don't know the exact series of events that proximately caused the first DNA. I don't think anybody does. But do you want to say that a deity turned inert matter (or "nothingness") -- poof! -- directly into the first DNA? If so, offer that as a hypothesis and present the data that you think supports that hypothesis. That will help us determine whether yours is a claim that we should accept.

    This is my big problem with those who refer to themselves as proponents of "intelligent design." I have yet to see one person who refers to him of herself as a proponent of "intelligent design" publicly offer one clear hypothesis. Which event(s) did the designer cause? I don't care who the designer is. I want to know what event(s) you think the designer caused. For instance, did the designer turn inert matter directly into the first self-replicating molecules on earth? Did the designer cause that meteorite to hit off the coast of Mexico 65 million years ago, triggering the extinction of the dinosaurs? Did the designer turn inert matter -- poof! -- directly into the first two elephants (one male and one female)? And what evidence, if any, suggests that the designer did what you think it did? This kind of information is important for the community of inquirers. Otherwise I don't know what to do with your claims.

    John A. Davison · 2 March 2005

    Wayne Francis
    I read your idiotic prediction and I am here only to tell you once more that I am through screwing around with a bunch of atheist ideologues who still believe in the most failed hypothesis in the history of science. You may now, with my permission, return to your fantasies. If you ever publish anything send me a reprint.

    John A. Davison

    Bob Maurus · 2 March 2005

    Spot on prediction, Wayne. I'm impressed.

    SteveF · 2 March 2005

    Actually John, I think its best that you spend time away from PT. After all, you are attempting to revolutionise modern science, that must surely require a considerable amount of effort. Maybe every time you think about posting here, you should remind yourself 'no, I must put the finishing touches to that paper I plan to submit to Nature.'

    In fact, if you do this, then I guess we will never see you around here again. All the media interviews and preparations for becoming the most famous scientist of your generation won't leave much room for messing around on a blog.

    Wayne Francis · 2 March 2005

    You still here JAD? Ah I see you've posted 4 times in less then 24 hours after you promised you where leaving us. Seems my idiotic prediction is 100% true. You keep saying to yourself that evolution is "the most failed hypothesis in the history of science" they say if you say something enough you begin to believe it. Problem is few others believe it in light of the evidence.

    The fact that you think shark placentas are the same as mammals and that the duck billed platypus's "bill" is structurally like a duck goes a long way to seeing what type of biologist you really are.

    Return to my fantasies? I'm still waiting for you to have me arrested by the FBI. Haven't you written to the Minister of Health here in Australia yet to get me fired and deported?

    The more you talk like you do the more obvious it becomes that I'm probably right about your paranoid schizophrenia/ You think there is a huge conspiracy to silence you. I feel it is that your peers silently tolerate your constant unstable outbursts at anyone that doesn't kiss your ass. Be thankful to them is all the advice I can give you.

    Maybe if you spent more time, or actually any time, in the lab trying to prove your hypothesis then your peers might take you a bit more seriously. Some how I think you'll stay at places like PT where you constantly pronounce how superior you are to everyone else.

    GCT · 2 March 2005

    Nature was created somehow. I hope that is acceptable to everyone.

    — John A Davison
    Unless you are expressing a personal opinion, no it is not acceptable to everyone. If it is a personal opinion, then it is acceptable for you to say it and then philosophize from that point. It is also acceptable to say that evolution does not deal with the formation/creation/whatever of nature, so it is moot. To make the statement you made, however, you must back it up with something.

    John A. Davison · 2 March 2005

    As usual Wayne Francis plays fast and loose with the truth. I never said evolution was the most failed hypthesis in the history of science. Evolution is undeniable. What I did say was that Darwinism is the most failed hypothesis in the history of science. This is just one more demonstration of the mindless conviction that Darwinism and evolution are synonyms. How stupid can anyone be to still believe in the Darwinian myth?

    Please, now that you have forced me to expose you for what you are, namely a liar, document where I ever proclaimed my superiority to anyone, or is that just another one of your knee jerk fantasies?

    There is no conspiracy to silence me, only one to ignore me, just at the Darwimps have ignored all their critics, from Mivart in Darwin's own day right up to the present. We simply don't exist.

    As for spending time in the laboratory, I have no laboratory and haven't had one for several years. Furthermore I don't need one as the molecular biologists and the chromosome mechanics are proving me correct every day as anyone with half a brain would realize if he would just read the literature.

    John A. Davison

    Wayne Francis · 2 March 2005

    John A. Davison not only seems to have paranoid schizophrenia but seems to have selective memory loss. In http://www.pandasthumb.org/pt-archives/000845.html#c18788Comment # 18788 he says

    Please, now that you have forced me to expose you for what you are, namely a liar, document where I ever proclaimed my superiority to anyone,

    — John A. Davison
    In http://www.pandasthumb.org/pt-archives/000654.html#c16458Comment # 16458 he says

    You jerks don't phase me with these infantile attacks on my competence and character. You are just a huge collection of unfulfilled sociopathic nobodies with nothing else in your empty lives but the autogratification you get from denigrating your intellectual superiors. You better keep your traps shut about my sources or I'll turn you all in to the FBI as security risks. Of course you have made that quite impossible haven't you with your cowardly anonymity. What a collection of losers/

    — John A. Davison
    Let me bold that "autogratification you get from denigrating your intellectual superiors." Seems I am, once again, in the position of showing you as making false statements. The fact is you've flown off the handle multiple times spouting babble that we should not question you. Your paranoid state was further proven when you went on and on about being censored because your stupid computer or isp was caching pages despite the fact that many people where explaining to you that you where not being censored and suggested means to which you could fix the problem. From memory it took you quite a few days to come around to the realisation that you where the one at fault. I'm actually surprised that you did

    I am sorry for the trouble I have may have caused. My computer has been acting up lately in several ways. In the meantime, let me make a brief statement about evolution.

    — John A. Davison
    Personally I would have apologised to the actual people that I blamed. On that I'll apologise for swapping "Darwinism" with "evolution". But you do claim evolution no longer occurs and it has been shown many times that it does even above the species level. Some how you want a whole new family to sprout forth in a decade or so to prove that evolution is still occurring.

    Glenn Shrom · 2 March 2005

    I was at the conference in Elizabethtown. For an irreducibly complex system, Niall Shanks presented two postulates and Michael Behe presented one. Shanks said that there could be a scaffolding - a simple system which builds up to a complex one, but then the simple parts disappear and only the complex is left. Shanks said that each part of a complex system could have formed as serving a simple purpose first, and then all the parts together cooperated to function for a new purpose after they were all individually in place. Behe said that all the parts could have formed together precisely to perform the function for which we observe them working together today.

    That is all his "intelligent design" theory really says. There is nothing about whether God exists or put things together in a perfect way or if there is any supernatural at all. Complex parts coming together exclusively for a function that they could not do individually leads on to all sorts of speculation about "designers", but it is really the most obvious explanation we have. Both of Shanks' postulates were way to limited to explain most of the biochemical systems we see today, let alone the complex systems such as vision. Can you imagine the lens being formed for a purpose other than vision, and the optic nerve also forming for some purpose other than vision, then also the retina, the iris, the pupil, the fluid inside the eyeball, etc.? And then once all the parts were in place they somehow discovered that they could also together work towards a new purpose which was for the organism to be able to see? It doesn't convince me.

    The scaffolding idea sounds a little more plausible, but it is hard to describe in any specific terms. What would the causal path look like for vision using a scaffold theory?

    Enough · 2 March 2005

    Glenn, I'm sorry, but you need to read more and write less.

    Enough · 2 March 2005

    Zimmer's recent articles on the evolution of the eye, posted on Pandas Thumb found by searching for "eye". Simple description. How could an elaborate set of components coming together somehow make more sense?

    http://www.corante.com/loom/archives/2005/02/15/eyes_part_one_opening_up_the_russian_doll.php
    http://www.corante.com/loom/archives/2005/02/16/eyes_part_two_fleas_fish_and_the_careful_art_of_deconstruction.php

    Stuart Weinstein · 2 March 2005

    Glen wrote:

    "That is all his "intelligent design" theory really says. There is nothing about whether God exists or put things together in a perfect way or if there is any supernatural at all. "

    I guess thats why Behe spends more time on discussing his theories on Christian TV then he does at scientific conferences. THis is why the Christian right is pushing ID. After all, they are well known for pushing things that have nothing to do with Christianity and God. THey are well known defenders of modern science, and they want just whats good for the scientific community.

    I hope you're not thinking that such Naivete is to be rewarded here.

    " Complex parts coming together exclusively for a function that they could not do individually leads on to all sorts of speculation about "designers", but it is really the most obvious explanation we have. Both of Shanks' postulates were way to limited to explain most of the biochemical systems we see today, let alone the complex systems such as vision. Can you imagine the lens being formed for a purpose other than vision, and the optic nerve also forming for some purpose other than vision, then also the retina, the iris, the pupil, the fluid inside the eyeball, etc.? "

    Hmmm... so you claim all useable eyes in nature have all of these parts?

    Interesting claim. I suggest you examine the great variety of eyes that are found in nature, and report back as to whether or not your ideas are borne out by the evidence.

    "And then once all the parts were in place they somehow discovered that they could also together work towards a new purpose which was for the organism to be able to see? It doesn't convince me."

    Me Either. Fortunately thats not what evolution suggests happened. On the other hand its a typical view hold by IDErs and creationists, the vast majority of which are wholly ignorant of how evolution works.

    Keanus · 2 March 2005

    I also attended the Elizabethtown day on ID, from morning to night, including all three debates and the capstone lecture in the evening by Paul Gross who dismembered ID, although, to be accurate, not in the eyes of many of the creationist/ID subscribers present who will hew to their beliefs until hell freezes over. The three debates included Behe vs.Niall Shanks on the science; John Haught (a Catholic theologian from Georgetown University) vs. David Martin (a local evangelical preacher); and Richard Thompson (president and chief counsel for the Thomas More Law Center and attorney for the Dover Area School Board) vs. VIc Walczak (Legal Director for Pennsylvania ACLU). I haven't had the time to write up my observations of the day but will do so tomorrow. There were some interesting exchanges, more in politics, legality and theology than in science, that I hope I can accurately describe tomorrow.

    Ed Darrell · 2 March 2005

    Glen, my experience is that ID advocates will specifically say that ID does not involve scaffolding. Scaffolding removes the need for an outside intelligence to intervene (since it explains, by natural, observable processes) the creation of things that only appear to be irreducible.

    Ask Behe, for example. I don't think he'd agree at all.

    John A. Davison · 3 March 2005

    As for the intellectual superiors to whom I referred, I was not, as Wayne Francis isisted, referring to myself but to such real honest-to-God bench and field scientists as Robert Broom, Leo Berg, Richard B. Goldschmidt, Otto Schindewolf, Reginald C. Punnett. Pierre Grasse, William Bateson, etc etc, not to such couch potatoes as Richard Dawkins, Stephen J. Gould, Ernst Mayr and William Provine. You clowns have your heroes and I have mine.

    "No sadder proof can be given by a man of his own littleness than disbelief in great men."
    Thomas Carlyle

    As for myself, if anyone ever bothered to read my Mnaifesto he would also discover the following on the first page:

    "A dwarf standing on the shoulders of a giant may see farther than a giant himself."

    John A. Davison

    GCT · 3 March 2005

    So, JAD, if you haven't claimed your superiority to anyone and you've also called us a bunch of losers, then you must be a loser too, right? Welcome to the club.

    John A. Davison · 3 March 2005

    Of course I am a loser. We are all losers in the game of life. Did I ever claim otherwise? Not that I can recall.

    John A. Davison

    John A. Davison · 3 March 2005

    Of course I am a loser. We are all losers in the game of life. Did I ever claim otherwise? Not that I can recall.

    John A. Davison